1.Effects of basic fibroblast growth factor and sucralfate on healing of experimental gastric ulcers in rats
Chinese Journal of Digestion 2001;0(04):-
Objective To investigate the effects of basic fibroblast growth factor(bFGF)and sucralfate on healing of experimental gastic ulcer in rats. Methods Thirty-two famale Sprage-Dawley rats were divide into 4 groups,averagely.bFGF 100 ng?100 g -1 ?d -1 , sucralfate 40 mg?100 g -1 ?d -1 , bFGF 100 ng?100 g -1 ?d -1 + sucralfate 40 mg?100 g -1 ?d -1 and normal saline were used in experimental gastric ulcer rats induced by acetic acid for 21 days. Contents of gastric acid and pepsin were measured,and the healing rate and quality of gastric ulcer and the number of capillaries in ulcer bed were evaluated. Results The amount of gastric acid and pepsin in bFGF group had no different from those of normal saline group. The ulcer areas in bFGF group and sucralfate group were (2.9 ?0.8) mm 2 and (3.2?1.2) mm 2 respectively,which were significantly smaller than that of normal saline group (6.8? 1.4 ) mm 2, P
2.Clinical Features of Elderly Subarachnoid Hemorrhage: 132 Cases Report
Chinese Journal of Rehabilitation Theory and Practice 2010;16(11):1075-1076
ObjectiveTo observe the clinical features, complications, and prognosis of subarachnoid hemorrhage (SAH) in the aged. Methods132 old cases were analyzed retrospectively. Results56.8% of patients complained headache as the main symptoms, 43.2% with dizziness or vertigo, 40.1% with disturbance of consciousness, 70.5% with negative of meningeal irritation sign. The most common cause is the aneurysm. The mortality was more in those complicated with hypertension. ConclusionSAH in the old characterized variable clinical manifestations, no special signs, half of them with good prognosis.
3.Ancient Chinese Model of Doctor-patient Relationship
Chinese Medical Ethics 1995;0(03):-
Doctor-patient relationship has attracted increasing attention.In the light of modern model to study the related theory,a preliminary study of the ancient Chinese doctor-patient relationship model has been done.The doctor-patient relationship in ancient society is the same complex and multi-level.Therefore,doctor-patient model could not be lumped together.According to the social status of patients and the extent of their demand for medical services,and the social status of doctors and their medical technique,the doctor-patient relationship could be divided into three typies-equality type,authority type,and principal and subordinate type.With a view of doctor-patient relationship of traditional Chinese medicine,there draws an acquisition value of the current complex patient relationship.
4.Effects of chemoimmunotherapy on lymphocyte subsets in patients with malignant tumors
Bonian HU ; Wei CHEN ; Qianjiang ZHAN
Chinese Journal of General Surgery 2001;0(09):-
Objective To study lymphocyte subsets changes in patients with malignant tumors during chemoimmunotherapy and the clinical significance. Metheds Fifty one cases were treated with chemotherapy and twenty six cases with chemoimmunotherapy. Lymphocyte subsets were determined by flow cytometry. Results Chemotherapy significantly decreased CD 3 +, CD 4 + and NK cells ( P 0 05). Chemoimmunotherapy elevated CD 8 + and NK cells ( P
5.The Diagnostic Strategy in Gastroesophageal Reflux Disease and the Role of Acid Inhibition Therapeutic Test
Jinkun LIN ; Pinjin HU ; Wei CHEN
Journal of Chinese Physician 2001;0(02):-
14,and/or pH4% of the total time at 24-hour esophageal pH metry were considered to be pathologic acid reflux(GERD).All patients underwent a diagnostic test by receiving lansoprazloe 30mg or placebo twice daily for 7 days through a cross-over design.A symptom reduction of over 75% was considered positive.Results 18(17%) cases of esophagitis were found in 104 patients by endoscopy.83(80%) patients experienced a typical symptom hearburn.87(84%) patients showed pathologic acid reflux detected from pH metry and they were considered to be GERD.85(82%) of 104 patients had positive result in therapeutic test.There was a significant correlation between both the diagnosis obtained from a trial of lansoprazole and the diagnosis obtained from pH metry(P
6.Current situation of HIV/AIDS voluntary counseling and testing in Jiangxi province
Chinese Journal of AIDS & STD 2006;0(04):-
Objective To analyze the current situation of voluntary counseling and testing(VCT) and improve HIV/AIDS prevention and control in Jiangxi province.Method VCT services in the province were analyzed using descriptive methodology.Result The province is in shortage of full time VCT workers.Of the individuals receiving pre-testing counseling,those receiving post-testing counseling and receiving referral counseling accounted for 5.22% and 1.39%,respectively.The individuals receiving tests mostly were aged 20-29 years,and a little less were aged 30-39 years.Higher positive rates of HIV screening tests were found in Pingxiang and Nanchang cities,accounting for 39.13% and 26.09%,respectively.Conclusion To improve VCT service and contain the spread of HIV/AIDS in this province,it is necessary to establish VCT networks,upgrade quality of counseling service and publicize VCT and its outreach activities among target population.
7.Advancement in the investigation of HLA-B27 associated anterior uveitis
Xiaofeng HU ; Wei, CHEN ; Hong, LU
Chinese Ophthalmic Research 2009;27(12):1150-1153
Uveitis is an important autoimmune disease.Human leukocyte antigen (HLA)-B27-associated anterior uveitis is the most common form of anterior uveitis.HLA-B27-associated anterior uveitis has distinct ocular,systemic,and genetic features.It attacks young subjects and leads to the damage of visual function due to the recurrence and complications.However,the pathologic mechanism of HLA-B27-associated anterior uveitis is still not thoroughly understood,and effective therapy is still unavailable.There are currently many experimental researches which attamp to study the etiology and develop an effective therapy for HLA-B27 acute anterior uveitis.Thus,various animal models of acute anterior uveitis such as endotoxin-induced uveitis and HLA-B27 transgenic animals including rat and mouse are established.Different therapy regimens have been designed both in clinical trial and experimental study and aquired promising achievements.Epidemiology,pathologic mechanism,different animal models and potential new therapies such as anti-TNFα,oral associated peptides tolerance and gene therapy are overviewed.
8.Studies on fingerprint of bidens bipinnata L.by HPLC
Liju ZHANG ; Wei HU ; Feihu CHEN
Chinese Journal of Primary Medicine and Pharmacy 2011;18(14):1875-1877
Objective The fingerprint method based on high-performance liquid chromatography for the quality control of bidens bipinnata L were firstly described and optimized. Methods HPLC system was used to obtain the fingerprint spectrum of bidens bipinnata L. The chromatography condition was ODS C18 column (4. 6mm×255mm,25μm),mobile phase Methanol-0. 2% HAc,and flow speed 1. 0ml ? min-1, detection wavelength 363nm.Results In this experiment,the standard fingerprint had been established and the similitude degree of 10 batches bidens bipinnata L. has also been obtained(0.941~0.999). Conclusion The method was accurate,reliable,good reproducibility, strong characteristic and could be used for the standard of general judgement and the quality estimation about the bidens bipinnata L.
9.Stroke Caused by Central Nervous System Vasculitis: 49 Cases Report
Wei HU ; Yun CHEN ; Ronghua TANG
Chinese Journal of Rehabilitation Theory and Practice 2009;15(11):1023-1024
Objective To explore the clinical manifestation of stroke caused by central nervous system vasculitis (CNSV). Methods 49 patients who suffered from stroke by CNSV were reviewed retrospectively. Results Among the 49 patients, 5 were intracerebral hemorrhage, 15 were ventricular hemorrhage, 7 were subarachnoid hemorrhage and 22 were cerebral infarction; the mean of age was (26.0±12.7) years old. Conclusion The clinical manifestation of stroke caused by CNSV is variform, and usually happens in young age. CNSV should be considered as the cause of stroke in adolescent.
10.Endovascular interventional treatment of bronchial artery aneurysm: case report and review of literature
Wei CHEN ; Xiaoyun HU ; Xuan WANG ; Jiasheng HUANG ; Chuanxian HU
Chinese Journal of Thoracic and Cardiovascular Surgery 2010;26(5):340-342
Objective To present one case of bronchial artery aneurysm successfully treated with endovascular interventional procedure and review literature. Methods A 67-year-old man was diagnosed with mediastinal bronchial artery aneurysm accompanied with tuberculous pleurisy by chest imaging. The aneurysm was treated via transcatheter bronchial artery embolization combined with endovascular stent-graft placement in the thoracic aorta under DSA guidance. Results Postprocedural angiography showed satisfactory exclusion of the aneurysm and no endolead. Conclusion Interventional therapeutic management of bronchial artery aneurysm is feasible and accurate.