1.The early diagnosis of lung cancer tumor -associated substance group and ferritin bronchoalveolar lavage fluid
Chinese Journal of Primary Medicine and Pharmacy 2016;23(15):2282-2284,2285
Objective To explore the early diagnosis of lung cancer in bronchoalveolar lavage fluid (BALF) in tumor -related substance groups (TSGF)and ferritin (SF),in order to provide a theoretical basis for clinical application.Methods 40 patients with lung cancer and 40 patients with benign lung disease were selected as the study objects,who were collected fasting blood and bronchoalveolar lavage fluid,using chemistry colorimetry to detect TSGF,using radioimmunoassay to detect SF.Results The serum TSGF,SF in the lung cancer patients were (80.43 ± 6.32)U /mL and (254.55 ±13.43)μg/L,which were significantly higher than the pulmonary benign lesion group (t =6.89,9.33,all P <0.05).The bronchoalveolar lavage fluid TSGF,SF in the lung cancer patients were (140.32 ± 11.45)U /mL and (365.87 ±23.65)μg/L,which were significantly higher benign than lung disease group(t =7.65, 12.38,all P <0.05).Bronchoalveolar lavage fluid TSGF and SF in patients with lung cancer were significantly higher than the serum,the difference were significant(t =7.41,8.94,all P <0.05).Conclusion Bronchoalveolar lavage fluid TSGF,SF detect for early diagnosis of lung cancer has a certain value,which were significantly better than the serum.So it can be clinically applicated.
2.Effects of Ningshen Mixture on Sexual Hormones,Interleukin-2 and the Therapeutic Effect in the Patient of Menopausal Syndrome
Journal of Traditional Chinese Medicine 1993;0(07):-
Objective:To explore effects of Ningshen Mixture on contents of sexual hormones,interleukin-2(IL-2)and the therapeutic effect in the patient of menopausal syndrome.Methods:Patients in the Ningshen Mixture group were treated with Ningshen Mixture and the control group with Gengnianan.Level of follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E_2)and IL-2 and the therapeutic effect were investigated.Results:After treatment E_2 level was increased in both groups with a significant difference as compared with that before treatment(P0.05).Conclusion:Ningshen Mixture can increase E_2 level,which is possibly one of the mechanisms.
3.Current status and outlook of pancreatic islets transplantation research
Journal of Interventional Radiology 2006;0(10):-
Diabetes is a common disease,serverely harmful to the human's health and life quality.The pancreatic islets transplantation can correct the patient's hyperglycemia,stop or even reverse the progress of the complication and thus decrease the mortality of diabetic patients.It is the most safe and efficient therapy for diabetes.Since the Edmonton Protocol got success in pancreatic islet transplantation in 2000,it has been more and more interested because of its great clinical curative effect.Research strategy of islet transplantation is now focussed on increasing the acquired islets with normal viability,selecting the best transplantation pathway,and improving the immunosuppression protocol.The shortage of human pancreatic donor is an ever unsolved problem in clinical application.The potential resolutions may include acquisition from xenogenic-islets;islets originated from stem cells,and islets from the living-donor human pancreas.The islets transplantation will open a new application field for interventional radiology.(J Intervent Radiol,2006,15: 577-579)
4.Clinical Observation of Sanqi Shengji Ointment Preventing Skin Flap Necrosis
China Pharmacy 2015;(20):2806-2807,2808
OBJECTIVE:To observe the clinical effects of Sanqi shengji ointment (SQSJO) preventing skin flap necrosis. METHODS:75 cases of local flap transfer in head and facial operation were randomly divided into blank group,treatment group, control group and with 25 cases in each group. After surgery,except for conventional treatment,treatment group was coated with SQSJO additionally;control group was additionally treated with rh-bFGF. The dressing was changed with iodophor in blank group conventionally till the wound healed. The skin flap necrosis,healing course,local skin temperature,swelling disappearance time and wound healing time were observed and compared among 3 groups after surgery. RESULTS:Compared with blank group,the incidence of skin flap necrosis decreased significantly in other 2 groups,there was statistical significance(P<0.05). There was sta-tistically significant difference in healing rate ameng 3 grups(P<0.05);there was no statistical significance in local skin tempera-ture among 3 groups after surgery (P>0.05);the flap swelling disappearance time and wound healing time of treatment group were significantly shorter than those of control group and blank group;there was statistical significance (P<0.05). CONCLU-SIONS:SQSJO can prevent skin flap necrosis accurately after flap transfer,and has no significant difference from rh-bFGF in pre-vention effect. Moreover,it is better than rh-bFGF in improving local swelling and shortening wound healing.
5.Assessment of left ventricular systolic synchronicity with omnidirectional M-mode echocardiography in dilated cardiomyopathy patients
Chinese Journal of Medical Imaging Technology 2009;25(10):1803-1805
Objective To assess left ventricular radial systolic synchronicity with omnidirectional M-mode echocardiography (OME). Methods OME examination was performed in 21 patients with dilated cardiomyopathy (DCM) and 27 healthy controls. The time to peak radial systolic movement were measured and adjusted by R-R interval. The standard deviation (Tc-SD)and the maximal temporal difference (Tc-dif) of the time to peak radial systolic movement of left ventricular short-axis segments at basal and mid-levels, the septal-to-posterior wall motion delay (SPWMD), septal-to-anterior wall motion delay (SAWMD), septal-to-laterior wall motion delay (SLWMD), septal-to-inferior wall motion delay (SIWMD) and anterior-to-inferior wall motion delay (AIWMD) were used as indicators of systolic dyssynchrony.Results Compared with the controls, Tc-dif, Tc-SD, SLWMD, SPWMD and SIWMD in basal level were significantly higher in the DCM group (P<0.05), while Tc-dif, Tc-SD, SAWMD, SPWMD, SIWMD and AIWMD in mid-level were significantly higher in the DCM group (P<0.05).Conclusion Omnidirectional M-mode echocardiography is useful to evaluate the radial systolic synchrony of the left ventricular in patients with dilated cardiomyopathy.
6.Advances in bioscaffolds applications repaired rotator cuff injury
Journal of Medical Postgraduates 2015;(4):441-444
Rotator cuff tears is a common cause of debilitating pain, reduced shoulder function, and weakness.Although the research progress for rotator cuff tear and surgical treatment has made great progress, rotator cuff repair failure rate still was ranged from 20 to 90%.Therefore it need new repair materials which can effectively improve the mechanical strength and stimulateg the intrinsic healing potential of the patient.In recent years, biological scaffolds used in rotator cuff repair has become a hotspot.This paper reviews the progress of scaffold materials on the treatment of rotator cuff injury.
7.Value of magnetic resonance imaging in diagnosis and prognosis prediction of brain stem injury at acute stage
Chinese Journal of Trauma 2010;26(3):199-202
Objective To study in patients characteristics of head CT and MRI of patients with brain stem injury at acute stage(<7 days)and discuss the relationship of head MRI manifestations and prognosis so as to provide indicators for imaging diagnosis and prognostic evaluation.Methods The patients with brain stem injury from November 2007 to September 2008 were involved in the study.Cranial CT and MRI were performed at early stage after brain stem injury.The patients were followed up for six months to evaluate prognosis and life quality of the patients based on disable rating scale(DRS)and Barthal score.Results MRI could detect more brain stem injuries than CT.The patients with injury at different parts of brain stem showed a statistical difference in regard of prognosis.Conclusions At acute stage of brain stem injury,cranial MRI has higher detection rate and clearer display of the brain stem lesions compared with CT.MRI manifestations can not only help classification of the brain stem injury,but also cater basis for diagnosis and prognosis evaluation of patients with brain stem injury.
8.Application of magnetic resonance spectroscopy in neurosurgery
Chinese Journal of Tissue Engineering Research 2007;0(04):-
As a minimally invasive method of examination, magnetic resonance spectroscopy can provide information of brain metabolism and biochemistry, objectively reflect brain metabolite changes. Different manifestations were described in the diseases such as brain injury and brain tumor. As a result, magnetic resonance spectroscopy can be a helpful technology to give information of diagnosis and prognosis in neurosurgery for brain injury, brain tumor as well as brain abscess and epilepsy.
9.Application of spinal stability rebuilding in symptomatic lumbar instability
Chinese Journal of Tissue Engineering Research 2007;0(04):-
Approximately 20 percent patients with symptomatic lumbar spinal instability, most of which occurs due to symptomatic degenerative lumbar spinal instability, trauma, tumor, and isthmus cleft, have no well results after expectant treatments. So they eventually receive reconstruction treatment to achieve thorough decompression and rebuilding of lumbar spinal stability. There are various kinds of treatments, and each of them has specific features. Therefore, the internal fixation and fusion methods should be selected according to patient condition to improve fusion rate, shorten bed staying duration and reduce complications. This paper summarized indications and features of each kind of operation as well as techniques of the interbody fusion.
10.Effect of Anrou-pressing and kneading Hegu (LI 4) and Sanyinjiao (SP 6) on uterine inertia during painless parturition
Journal of Acupuncture and Tuina Science 2021;19(1):67-71
Objective: To observe the effect of Anrou-pressing and kneading Hegu (LI 4) and Sanyinjiao (SP 6) on uterine inertia during painless parturition. Methods: A total of 100 cases of patients with uterine inertia during painless parturition were randomized into an acupoint group and a medicine group by the SPSS programming, with 50 cases in each group. Patients in the acupoint group received the treatment of Anrou-pressing and kneading bilateral Hegu (LI 4) and Sanyinjiao (SP 6), while patients in the medicine group received intravenous oxytocin. The labor time and maternal-child safety were evaluated, and the labor stage was compared. Results: The latent and active phases in the 1st labor stage and the 2nd labor stage in the acupoint group were substantially shorter than those in the medicine group, and the between-group comparisons showed statistical significance (all P<0.05). The between-group comparison of the 3rd labor stage showed no statistical significance (P>0.05). The postpartum hemorrhage amount in both groups was within the safe range, and the between-group comparison showed no statistical significance (P>0.05). The newborn 1 min Apgar score was ranged 8-10 points, and the between-group comparison showed no statistical significance (P>0.05). The between-group comparison of the labor stage efficacy showed statistical significance (P<0.01), with a better progression in the acupoint group. Conclusion: Anrou-pressing and kneading Hegu (LI 4) and Sanyinjiao (SP 6) is both effective and safe for uterine inertia during painless parturition.