AIM To develop a comparative method for studying on the HPLC/UV/MS fingerprints of triterpene acid in the leaves and the seeds of Lagerstroemia specious L. METHODS Separation was performed on LunaC_ 18 (2.6 mm?250 mm, 5 ?)analytical column, The mobile phase was composed of acetonitrile and 0.1 % formic acid as gradient eluent. The flow rate was 1.0 ml?min -1 . RESULTS Both of corosolic acid and maslinic acid existed in the leaves and the seeds of Lagerstroemia specious L. Ursolic acid existed in the leaves and the oleanolic acid contained in the seeds of Lagerstroemia speciouswere L. CONCLUSION The method can be used for quality control of the leaves and the seeds of Lagerstroemia specious L.

China ; History, 20th Century ; Humans ; Integrative Medicine ; history ; Medical Oncology ; history ; Physicians ; Portraits as Topic

The physicochemical properties and functional activities of chitooligosaccharides are more superior than chitin and chitosan, so chitooligosaccharides becomes a new developing kind of functional oligosaccharides worldwide in recent years. Research development of the physiological activities of chitooligosaccharides such as antibacterial activity, antitumor activity, protective effect on bacterial infection in vivo , regulation of plant physiology, proliferation of bifidobacteria and anti-mutagenic activity was reported in China and a-broad, meanwhile, application prospect were forecasted as well in the paper.

Objective To investigate the clinical features and treatment programs in children with Takayasu arteritis (TA) in order to improve awareness of the disease. Methods A retrospective study of hospi-talized children with TA in our hospital from Jan. 1999 to Dec. 2012 was performed. Results Between the 15 patients with TA, the ratio of male to female was 1∶2. The onset was from 14 months to 15 years old, with average age at (10 ±4) years old. It is according to (the European League against Rheumatism/the Pediatric Rheumatology European Society (EULAR/PRES) criteria for the diagnosis of TA. The most common clinical manifestations are hypertension, which occurred in 13 cases(87%), weak pulse or pulseless in 11 cases (73%), and heart failure in 10 cases (67%). About two-thirds of patients were diagnosed when the onset of heart failure occurred. The most common clinical type was type Ⅱ, which occrred in 9 cases (60%). Antihypertensive drugs, oral steroid and congestive heart failure controlling were the main treatment. Three patients with positive purifiedproteinderivative (PPD) test received anti-TB treatment. Three patients had vascular bypass surgery, one patient had percutaneous transluminal angioplasty. Conclusion TA may be life-threatening and progressive. Many patients are with advanced disease at the time of treatment, so the prognosis is generally poor. Early recognition is necessary to initiate appropriate therapy. The disease should be considered in patients with unexplained arterial hypertension or unexplained inflammatory syndromes without local signs.

Many reasons cause low back pain, such as muscles and ligaments injury, vertebral joints retrogression, spinal canal stenosis, lumbar disc herniation, lumbar spondylolisthesis, spondyloarthritis, infection, tumor and metabolic bone disease. It is in recent years that discogenic low back pain be recognised, especially after the MRI widely applied in clinics. This article makes a summary on discogenic low back pain of recent years from etiology, pathogenesis, diagnosis and therapy.

Objective To study the relationship between the serum level of cholinesterase (CHE) and patient's clinical characteristics and serum levels of lactic dehydrogenate(LDH) and β2-microglobulin (β2-MG) in non-Hodgkin lymphoma(NHL) patients. Methods The levels of CHE, LDH, β2-MG were detected with rate method and immunoassay respectively in 74 patients, and then these patients were divided into low (38 patients) and high level groups (36 patients) according to the serum CHE levels, compared with clinical characteristics and serum levels of LDH and β2-MG between the two groups. Results There were a significant difference in serum levels of CHE, LDH, β2-MG between the low and the high CHE level group [(3714.2 ±1207.1) U/L, (435.7±364.4) U/L, (4.3±2.9) mg/L; (7898.2± 1550.5) U/L, (247.4±134.8) U/L, (2.7±1.2) mg/L, respectively] (t =10.510, P =0.000; t =2.969, P =0.005; t =3.043, P =0.004, respectively). There were no statically significance in age, pathology type, leukocyte and platelet between the low and high serum CHE level groups (t =0.166, P =0.868; x2 =0.751, P=0.386; t =1.626, P=0.111; t =1.987, P=0.056, respectively). Patients with low CHE level group were mostly in Ann Arbor Ⅲ-Ⅳ period (x2 =9.394, P =0.024) and mostly male patients compared with the high CHE level group patients (x2 =5.432, P =0.020). The quantity of hemoglobin in the low CHE level group(97.6±25.8) g/L were lower than that of the high level group (113.4±15.2) g/L (t = 3.230, P =0.002). Conclusion The low CHE level was not correlated with age, pathology type, leukocyte and platelet, but was related with male, Ann Arbor Ⅲ-Ⅳ period, anemia, and higher expression of LDH, β2-MG.

Acute appendicitis is the most common surgical or acute abdomen in childhood.Rapid and correct diagnosis is the premise of rational therapy,but there are still some problems in diagnosis and differential diagnosis.Sufficient comprehension about clinical features and differential diagnostic diseases,typical clinical symptoms,physical examination,laboratory examinations,ultrasonography or CT would make a definite diagnosis.Laparoscopy is also used to make a diagnosis if necessary.

OBJECTIVE To investigate the evolution of drug-resistance of Staphylococcus aureus in children in Hubei tertiary level hospitals during four years and provide the evidence for clinically reasonable use of antibiotics.METHODS The summary data of drug sensitivity in clinical isolates of meticillin-resistant S.aureus(MRSA) and meticillin-sensitive S.aureus(MSSA) in children in Hubei tertiary level hospitals from 2004 to 2007 were investigated retrospectively and the results were analyzed statistically.RESULTS The tendency of infections with MRSA upgraded yearly during four years(5.7%→10.7%→40.8%→46.9%);the resistance rates of MRSA to various antibiotics were all higher than that of MSSA.The vancomycin-resistant S.aureus had not been detected.CONCLUSIONS The drug-resistance status of SA in Hubei is still very serious.We should adopt effective measurement to control the occurring and epidemic outbreak in combination with children physiological characteristic.

Objective To understand the Wuxi area index detection of infectious blood donors in the blood situation,in order to take targeted measures to block the blood-borne diseases.Methods From 2005 to 2012,Wuxi area (not including county, district)blood donation blood samples 329 254 (person)copies of the test results were retrospectively analyzed.Results 8 years,Wuxi unpaid donors HBsAg,anti-HCV,anti-HIV,and anti-TP four tested positive rates were 0.587%,0.452%, 0.212% and 0.509%,the total positive rate was 1.76%.Different years of anti-HCV,anti-HIV and anti-TP positive rate difference was statistically significant (χ2= 40.74~138.24,P<0.01).From 2011 to 2012 HBsAg positive rate was signifi-cantly increased,and compared with the previous year,difference was statistically significant (χ2=47.56,52.34,P<0.01), while four the number of positive indicators of infection in different sex,age and occupation with different proportions of dis-tribution.Conclusion The positive rate of most indicators declined year by year,but there was still an upward trend in indi-vidual proj ects.Should further improve the different groups of scientific blood donation advocacy work to ensure blood safe-ty.

[Objective] Through a meta-analysis to compare the effectiveness and safety of traditional Chinese medicine and western medicine in the treat-ment of chronic atrophic gastritis(CAG) with dysplasia . [Methods] Randomized clinical trials(RCTs) which compared traditional Chinese medicine and western medicine for chronic atrophic gastritis with dysplasia in PubMed, Cochrane library, WanFang and CNKI were searched. The patients which were analyzed were divided into two groups: western medicine and traditional Chinese medicine.Statistical heterogeneity between trials was evaluated by RevMan5.0. Heterogeneity of the included articles was tested and used to select proper effective model for calculation.Publication bias was investigated through visual inspection of funnel plots and Egger's regression model.[Results] 6 RCTs including 632 patients were analyzed. The total odd ratios(OR) of clinical symptoms,gastroscope symptoms,pathological symptoms by traditional Chinese medicine were higher than western medicine, the OR values were 3.40(95%CI:2.18~5.31,P<0.01),4.14(95%CI:2.37~7.20,P<0.01),2.94(95%CI:1.77~4.90,P<0.01),3.71(95%CI:2.29~6.02,P<0.01),4.41(95%CI:2.75~7.07,P<0.01),5.21 (95%CI:3.65~7.43,P<0.01). Inspection of the funnel plots for al outcome measures did not reveal evidence of publication bias( P=0.81, 0.41, 0.29, 0.88, 0.44, 0.82, respectively).[Conclusions] The treatment of chronic atrophic gastritis with dysplasia by traditional Chinese medicine can improve the excel ent response rate, overal response rate of clinical symptoms,gastroscope symptoms,pathological symptoms better than its purely western medicine treatment efficacy.