Objective To study the CT and MRI findings of ganglioneuroma and compare with pathology . Methods Clinical data of 12 patients with ganglioneuroma confirmed by surgical pathology were retrospectively ana -lyzed.All patients underwent CT and MRI , and the results were compared with pathological results .Results The average size of the lesion was (4.7 ±1.2)cm,CT scan was uneven or uniform density.In MRI plain scan,T1WI showed heterogeneous low signal ,T2 WI showed uneven contour signal ,the middle part of the strip of low signal .12 cases received enhanced MRI scan ,there were four cases of non-enhanced,mild enhancement in 3 cases,uniformity progres-sive strength enhanced with two cases ,uneven progressive enhancement in 3 cases,there was 1 patient with edge of the annular reinforcing ,in accordance with CT scan results .Conclusion When CT and MRI used as the detection means of ganglioneuroma ,its performance has a certain characteristic ,and that reflects in large part the tumor shape ,size and tis-sue composition .And pathological tumor is rich in a lot of mucus matrix has a certain relationship .

OBJECTIVE:To evaluate the perioperative utilization of antibacterial drugs in patients undergoing modified radical mastectomy. METHODS: In this retrospective study, the perioperative utilization of antibacterial drugs in patients who underwent modified radical mastectomy during 2006 and 2006 were analyzed statistically. RESULTS: 100% of the patients received antibacterial drugs preventively. The problems involved in the preventive use of antibacterials manifested as medication without indications, irrational application of broad-spectrum antibacterials, frequent change of drugs, blind drug combination, inappropriate time of initial administration and prolonged drug use etc. CONCLUSION: The perioperative use of antibacterial drugs in patients undergoing modified radical mastectomy in our hospital is far from rational. The Clinicians' medication behavior should be standardized and supervision on rational drug use should be strengthened.

OBJECTIVE: To discuss the clinical characteristics and the patterns of allergic reaction(ADR) caused by aminoglycosides.METHODS: 98 ADR cases induced by aminoglycosides were retrieved from domestic journals reported from Jan.1990 to June 2007 for a statistical analysis.RESULTS: The ADR of aminoglycosides was closely related to route of administration,unreasonable application,allergic history,etc.CONCLUSION: The ADR of aminoglycosides and rational use of aminoglycosides should be strengthened further in the clinical practice.

Congenital anorectal malformation(CAM) is one of the most common colorectal diseases in children. Anoplasty has been the only treatment. Because of the fact that anorectal malformation is constantly complicated with congenital defect in the nerve and musculature, postoperative difficulty in defecation is common. Poor long-term quality of life of these affected children is a burden to the children, family, and society. With the advance of modern medicine, emphasizing the functional recovery after anatomical reconstruction of anorectum and conduction of individualized biofeedback training program to improve the defecatory function and long-term quality of life are the new treatment concepts and important progress. Novel methods for the prevention and treatment of CAM are still under exploration.
Anorectal Malformations ; Anus, Imperforate ; surgery ; Child ; China ; Digestive System Surgical Procedures ; Fecal Incontinence ; surgery ; Humans

China ; epidemiology ; Diagnostic Techniques and Procedures ; Epidemiologic Studies ; Hematologic Diseases ; diagnosis ; epidemiology ; Humans ; Incidence ; Meta-Analysis as Topic ; Multicenter Studies as Topic ; Prevalence ; Randomized Controlled Trials as Topic

The second edition physiology published by People's Health Publishing House has been re-drawn and added many illustrations. The illustrations of the new version have improved significantly in the clarity,aesthetics,science,information-rich,etc.It will help to improve the quality of teaching.Some experiences can be got by drawing: First, it is necessary to fully understand the physiological knowledge.Second,one of reference materials should be selected as a template to make creative working.Third,some basic principles should be followed,such as reasonable layout,appropriate grayscale,rich content,simple composition,etc.

Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease. The etiology and pathogenesis are still unclear. Nowadays there is a lack of an effective molecular marker which can effectively assist the early diagnosis and prognosis of this disease. This article reviewed the pathological anatomy, diagnostic criteria, subtypes and clinical manifestations, imaging studies, scales evaluation, treat-ment and rehabilitation, complications and risk factors of PSP. Patients with PSP should be managed by a multidisciplinary team. The man-agement of PSP should include the rehabilitation of disorder and palliative treatment, as well as support and education, to improve the quali-ty of life for patients and their caregivers.

AIM: To investigate the infection of huma n embryo fibroblasts (HF) with CMV as well as the effect of CMV on ?-actin and mi crofilaments. METHODS: RT-PCR assay was used to detect the mRNA expression of CMV immediate early (IE) gene, ?-actin and GAPDH genes in HF cells infected wit h CMV. The morphological changes and microfilaments in infected cells were obser ved with transmission electron microscopy. RESULTS: The morphology of HF cells infected with CMV changed si gnificantly from fusiform shape to round shape. The mRNA expression of CMV immed iate early gene was detected. The increase in mRNA level of IE gene was parallel with the infected titer of CMV. However, t he expression level of ?-actin mRNA in HF cells infected with CMV was decreased compared with the uninfected cells, while the expression of GAPDH mRNA did not change. CMV particles were observed in the cells by electron microscope. Microfi laments were found ruptured and shortened after the infection of CMV. CONCLUSIONS: CMV was able to infect human embryo fibroblasts and replicated in the cells. Also the CMV infection affected the expressi on of ?-actin mRNA and the microfilaments.

Objective To discuss the perioperative nursing care of patients who is going to receive interventional therapy for hepatic artery stenosis after liver transplantation and to provide useful reference for reducing surgery-related complication and for improving the prognosis of patients. Methods Based on the patient's condition and operative requirement,we provided effective nursing care for 20 patients who were admitted to receive the interventional therapy for hepatic artery stenosis after liver transplantation. The nursing care included preoperative preparation,postoperative nursing and medical guidance at the time of discharge. Results Interventional therapy was successfully performed in all 20 cases,and no hemorrhagic tendency or acute thrombosis occurred. Marked symptomatic improvement was obtained in all patients. Conclusion The interventional therapy is an effective treatment for hepatic artery stenosis after liver transplantation. Intensive perioperative nursing care can well prevent the occurrence of surgery-related complications and can surely improve the therapeutic results.

Objective To investigate the therapeutic effect of bundle treatments for critically ill patients with pulmonary tuberculosis and respiratory failure (RF).Methods A prospective study was conducted, including 56 patients with pulmonary tuberculosis and RF necessary for invasive mechanical ventilation admitted into Department of Critical Care Medicine of the Fourth People's Hospital of Nanning City from January 2013 to December 2014 as the observation group to be treated by bundle treatments. A series of treatments and cares were given to the critically ill patients, such as invasive mechanical ventilation, application of antibiotics by experience within the first hour, supportive treatment targeted to hemodynamics in early stage, correction of brain dysfunction, effective therapy for tuberculosis, establishment of enteral nutrition in early stage and prevention of ventilator-associated pneumonia (VAP), etc. All the above treatments were completed one by one in 6 hours to 12 hours. Meanwhile, 42 patients who hospitalized from January 2011 to December 2012 and treated with conventional targeted therapy were designed as the control group. The changes of vital signs, blood routine test, respiration, liver, kidney, etc organ functions, the improvement of acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) score, expected mortality and sequential organ failure assessment (SOFA) score, the incidence of VAP, cure and improvement rate, mortality, duration of invasive mechanical ventilation, the length of stay in intensive care unit (ICU) were compared between the two groups after treatments.Results There were no statistically significant differences in the comparisons between the two groups before and after treatments in temperature, white blood cell count (WBC), blood glucose, total bilirubin (TBil), alanine transaminase (ALT), albumin (Alb) and cholesterol level (allP > 0.05), except the platelet (PLT) count in observation group was higher than that in control group before treatments. After treatments for 72 hours, in the two groups, the heart rate (HR), respiration rate (RR), APACHE Ⅱ score and expected mortality were lower than those before treatments, while the arterial partial pressure of oxygen (PaO2) and oxygenation index were higher than those before treatments. There were no statistically significant differences in pH value, PLT, arterial partial pressure of carbon dioxide (PaCO2) and SOFA score before and after treatments in the control group (allP > 0.05). In the observation group, after treatments, the pH value was increased compared with that before treatments, while PLT, PaCO2 and SOFA score were decreased compared with those before treatments (allP < 0.05). The degrees of improvement of PaCO2 and oxygenation index in the observation group were superior to those in the control group [PaCO2 (mmHg, 1 mmHg = 0.133 kPa): 43.32±9.10 vs. 56.10±9.39, oxygenation index (mmHg): 330.60±100.98 vs. 245.65±83.20, bothP < 0.05]. After bundle treatments, compared with control group, the incidence of VAP was decreased [16.07% (9/56) vs. 33.33% (14/42),P < 0.05], improvement and cure rate was increased [78.57% (44/56) vs. 59.52% (25/42),P < 0.05] and mortality was decreased significantly in observation group [10.71% (6/56) vs. 28.57% (12/42),P < 0.05]. The duration of invasive mechanical ventilation (days: 9.15±3.59 vs. 16.96±13.44) and the length of stay in ICU (days: 13.30±4.24 vs. 23.00±15.03) in the observation group were shorter than those in the control group, but no statistically significant differences were found (bothP > 0.05).Conclusion The bundle treatments can effectively reduce the incidence of VAP and elevate the improvement and cure rate in patients with pulmonary tuberculosis complicated with RF.