1.Clinical analysis of six cases of early nasal lymphoma.
Qunfang YUAN ; Wei WANG ; Ming ZHOU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(15):856-857
Adult
;
Aged
;
Female
;
Humans
;
Lymphoma
;
Male
;
Middle Aged
;
Nose Neoplasms
2.Application of digital tomosynthesis in the diagnosis of occult fracture of scaphoid bone
Ming CHEN ; Wei CHEN ; Wusheng YUAN
China Medical Equipment 2015;(1):116-117,118
Objective:To discuss the X-ray digital tomosynthesis (Digital Tomosynthesis, DTS) application value in the occult fractures of the scaphoid. Methods: we selected 19 patients in our hospital in 2012 examined by DTS, who were negative or highly suspicious of occult fracture with X-ray examination, and spiral CT (SCT) three-dimensional (3D) reconstructions were applied in seven patients. Results:There were 17 patients with fracture by DTS.7 patients showed fracture by spiral CT(SCT) three-dimensional(3D) reconstructions. Conclusion:Compared with X-ray examination, the image quality of Digital Tomosynthesis (DTS) is higher, which can show occult fracture better. Compared with CT, DTS can show spatial location of bony anatomy more clearly and can obtain more detailed information. With the important extension and supplement of CT and MRI, the distal tomosynthesisis is worth to be generalized for lower radiation, lower price, higher positive rate and high quality of the pictures.
4.Epidemiological analysis of occupational diseases in Zhejiang province China during 2006-2010.
Wei-ming YUAN ; Xing-lin FANG ; Bai-qi WU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2013;31(4):279-281
Adolescent
;
Adult
;
Aged
;
China
;
epidemiology
;
Female
;
Humans
;
Male
;
Middle Aged
;
Occupational Diseases
;
epidemiology
;
Young Adult
5.Effect of Yiqi Huoxue therapy on vascular endothelial growth factor in retina of diabetic rats
Wei YUAN ; Ming JIN ; Lin PAN ; Hui DENG ; Haidan LIU
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(05):-
0.05).The model group rats displayed high expression of VEGF.Compared with the model group,the expression of VEGF in Yiqi Huoxue medicine group decreased evidently(P
6.Quantitative detection of the expression level of transform-ing growth factor-β and its receptors in pterygium with RT- PCR
Ming, ZHONG ; Wei, SHEN ; Qing, FU ; Yuan, ZHANG
International Eye Science 2009;09(4):619-622
AIM: To quantitatively investigate transforming growth factor-β(TGF-β) and its receptors in normal bulbar conjunctival tissues and pterygium tissues. METHODS: Thirty cases of pterygium patients were randomly selected to undergo surgical resection of pterygium lesion, and the normal margin of bulbar con-junctival tissues were collected as control. Gene expres-sion was detected quantitatively by the method of quantitative real-time PCR (QRT-PCR) analysis. RESULTS: The expression level of TGF-β1 and TGF-β2 was 4.26×10-7±1.45×10-7 and 1.08×10-10±0.68×10-10 in normal bulbar conjunctival tissues, while 10.67×10-7±7.47×10-7 and 8.23×10-11±6.63×10-11 in pterygium tissues. The expression level of TGF-βRⅠand TGF-βRⅡwas 0.003015±0.0036 and 5.33×10-5±5.05×10-5in normal bulbar conjunctival tissues, while 0.000379±0.000281 and 1.002×10-5±9.04×10-6 in pterygium tissues. The expression level of TGF-β1 and TGF-β2 in pterygium was elevated (P<0.01). TGF-β1 expression level in pterygium increase 2.9±2.8 times than in normal conjunctiva. TGF-β2 expression level in pterygium increase 7.5±1.4 times than in normal conjunctiva. The expression level of TGF-βRⅠin pterygium was significantly lower (P<0.05). The expression level of TGF-βRII in pterygium was significantly lower (P<0.01). CONCLUSION: QRT-PCR is an effective method to quantitatively detect gene expression in eye. The upregulation of TGF-β1 and TGF-β2 and downregulation of their receptors expression may play an important role in the pathogenesis of pterygium, which is noteworthy further investigation in diagnosis and treatment of pterygium.real-time PCR; gene expression
7.Explore Xueshuan Xinmaining tablet effecting on treatment outcome of coronary heart disease based on propensity score.
Yuan LI ; Yan-ming XIE ; Yan LIU ; Wei ZHAO
China Journal of Chinese Materia Medica 2015;40(24):4791-4796
Xueshuan Xinmaining tablet is a Chinese patent medicine for treating chest pain caused by blood stasis. It is widely used in clinical prevention and treatment of coronary heart disease. In order to understand the treatment effect of Xueshuan Xinmaining tablet in patients with coronary heart disease, we extracted electronic medical record data from 18 large hospitals nationwide. We matched the coronary artery disease patients with or without Xueshuan Xinmaining tablet treatment on gender, age, condition at admission and whether combined with cardiac insufficiency on a one to one ratio. After matching, both groups, patients using Xueshuan Xinmaining tablet (group A) and patients not using Xueshuan Xinmaining tablet (group B), ended up with 1,122 people. In order to evaluate the effectiveness of treatment, the endpoint of effective group was defined as "cure" and "better" while the endpoint of invalid group was defined as "invalid" and "death". Chi-square test showed a statistical significant difference (P < 0.05) between the two groups of patients with coronary heart disease, with a higher efficiency in Xueshuan Xinmaining group. Classic logistic regression analysis showed no statistical significant difference between the two groups on treatment outcome efficiency. Generalized boosted models (GBM) and propensity score (PS) weighted Logistic regression were then applied to balance 45 variables between the two groups. The results showed a regression coefficient greater than 0 and a statistical significant difference (P < 0.05) between the two groups. Based on the existing results of the analysis, we considered that coronary heart disease patients using Xueshuan Xinmaining tablet had a higher efficiency in clinical efficiency than the patients not using Xueshuan Xinmaining tablet. Since this study did not certainly eliminate all the possible confounders and patients from the hospitals included in this study were not yet well represent the overall situation of the source population, the study conclusion only provided drug use reference for clinical doctors for coronary heart disease. Large randomized controlled trials needs to be done for more reliable results to guide clinical rational and effective medication.
Adolescent
;
Adult
;
Aged
;
Coronary Artery Disease
;
drug therapy
;
Drugs, Chinese Herbal
;
therapeutic use
;
Female
;
Humans
;
Logistic Models
;
Male
;
Middle Aged
;
Propensity Score
;
Tablets
8.Neoplasty of multiple cerebrospinal fluid rhinorrhea on combined frontal-nose approach through endoscope.
Wei-Yuan SUN ; Fu-Ming ZHU ; Xin-Hua XU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2008;43(6):460-462
Cerebrospinal Fluid Rhinorrhea
;
surgery
;
Craniotomy
;
methods
;
Endoscopy
;
Frontal Sinus
;
surgery
;
Humans
;
Male
;
Nose
;
surgery
;
Reconstructive Surgical Procedures
;
methods
;
Young Adult
10.Observation on clinical therapeutic effect of Alprostadil combined with Magnesium Isoglycyrrhizinate on patients with Hepatocirrhosis at active phase
Hong LI ; Yuan HE ; Ming WEI ; Rui HE
Chinese Journal of Primary Medicine and Pharmacy 2010;17(22):3068-3069
Objective To evaluate the effect of Alprostsdil combined with Magnesium Isoglycyrrhizinate on hepatocirrhosis at active phase. Method 74 inpatients collected from our hospital were randomly divided into control group(37 cases)and treatment group(37 cases). The patients in control group were given conventional liver protecting treatment. In addition to routine therapy of the control group, the patients in treatment group received intravenous Alprostadil and Magnesium Isoglycyrrhizinate injection once a day for 4 weeks. Results The total effective rate of treatment group was 67. 6%, and that of control group was 40. 5%, and the difference was significant (P < 0. 05).Conclusion Alprostadil combined with Magnesium Isoglycyrrhizinate has good clinical therapeutic effect on hepatocirrhosis at active phase.