The discipline of nutrition has been developing quickly in the past 30 years in China,and a number of scientific progress has been achieved.Some new discoveries have been unveiled in terms of treatment and prevention of liver carcinoma,colon cancer,and breast cancer by certain nutrients.Besides,the application of nutrition in the prevention and treatlnents of metabolic diseases such as obesity.diabetes mellitus and congenital malfcIrmation has been studied.Furthermore,academic achievements in the treatment of tumor and metabolic diseases by integrating nutritional therapies has also been made.The establishment of relevant organizations and institutes as well as the prosperous performance of nutrition education contribute to the development of discipline of nutrition in China.

Child Nutrition Sciences ; Health Knowledge, Attitudes, Practice ; Humans ; Physicians

Objective The purpose of this study was to examine the effects of exercise training on cardiac function and automatic nervous activity in patients with coronary artery disease(CAD) following PTCA or intracoronary stent implantation. Methods For this study, 37 CAD patients (28 men and 9 women; aged 56.23 ?11.16 years) participated in a supervised 8-week training program with 35 healthy controls(27 men and 8 women; aged 55.72 ?10.34 years). Cardiac function was assessed with indexes obtained during exercise testing using the standard Bruce protocol (submaximal gradural treadmill exercise) before and after 8 weeks training. Meanwhile, heart rate variability (HRV) was used to value the automatic nervous activity. Results After 8 weeks, the margin between maximal HR and resting HR (△HR=HR max-HR resting) was significantly broader (P

Objective To observe and analyze the characteristics and trends of the liver and gallbladder damage caused by long-term use of anti schizophrenia drugs through the observation of the abdominal ultrasound. Methods From August 2013 to April 2016, the patients diagnosed as schizophrenia and met criterions were enrolled in our hospital. The observation group I included patients taking anti schizophrenia drug for 3 to 5 years. The observation group II included patients taking anti schizophrenia drug more than 5 years. In addition, the control group recruited healthy person who were over 30 years old and had never taken anti-schizophrenia drug. The change in ultrasound of liver and gallbladder were recorded and analyzed. Results The rate of cholecystolithiasis, chronic cholecystitis in observation group II were higher than those in the other two groups (P<0.05), while there had no significant difference between observation group I and control group. The rate of pure fatty liver in observation group II were higher than those incontrol group (P<0.05), while there had no significant difference between observation group I and observation group II, and there had no significant difference between observation group I and control group. There had no significant difference among three groups regarding as the rate of hepatic cyst and hepatic cavernous hemangioma. Conclusion Long-term use of anti-schizophrenia drugs could increase the risk ofcholecystolithiasis, chronic cholecystitis and pure fatty liver .

Integrin is a main factor that mediates adhesive attraction between the cell and the extracellular matrix,and it participates in the formation of new vessel lumens and the construction of the rete vasculosum by regulating endothelial cell adhesion and migration.The extracellular matrix is the ligand of integrin.Collagen and laminin's deposition form new vessel lumens.The vascular endothelial growth factor promotes the proliferation of endothelial cells,accelerates angiogenesis and increases the permeability of blood vessels.This review focuses on the roles and correlation of integrin and VEGF in angiogenesis.

BACKGROUND:White blood cells involved in the inflammatory response play an important role in deep vein thrombosis.E-selectin mediates the initial process of white blood cell and vascular endothelial cell attachment during inflammation.OBJECTIVE:To investigate the relationship between deep venous thrombosis(DVT) and plasma E-selectin.DESIGN,TIME AND SETTING:Completely random design and linear correlation analysis were performed at Department of Vascular Surgery,First Affiliated Hospital of Chongqing Medical University and Clinical Diagnostic Laboratory of Chongqing Medical University from September to December 2007.PARTICIPANTS:Twenty-seven cases of deep vein thrombosis,16 males and 11 females with an average age of(57 ? 15) years,were selected,who attacked within 3 days or with aggregated condition.METHODS:Blood samples were obtained at the admission of the patients.After 72 hours,a second specimen was obtained,defined by thrombolysis and anticoagulant therapy.Determination of plasma E-selectin by ELISA and the blood coagulation abilities and platelet count of the 1st blood samples were performed,including part-time activation thromboplastin,prothrombin time,and plasma fibrinogen.MAIN OUTCOME MEASURES:E-selectin levels before and after treatment,blood coagulation abilities before treatment,platelet determination and E-selectin related analysis.RESULTS:No acute pulmonary embolism occurred in 27 cases of deep vein thrombosis during the treatment.One case underwent routine Forgart of thrombectomy catheter,and of the other 26 cases,15 were significantly improved,and 11 were not improved after 72 hours.Plasma E-selectin levels significantly decreased after thrombolysis,anticoagulant therapy in deep vein thrombosis patients with clinical remission(P = 0.001),but the plasma E-selectin levels were increased in those with no remission(P = 0.003).E-selectin levels and platelet count of deep vein thrombosis in patients before treatment showed no correlation(r =-0.113,P = 0.576),and were not related to fibrinogen content(r =-0.050,P = 0.802),or part-time activation thromboplastin(r=-0.046,P=0.822),and prothrombin time(r=-0.080,P=0.690).CONCLUSION:Plasma E-selectin levels are positively related to deep vein thrombosis severity.

Energy metabolism refers to the metabolism of three major nutrients associated with the process of energy production and usage.The metabolism in patients with tumors manifests specifically, as a result of tumor-bearing state, host's response to tumor and anti-neoplastic therapy.It is believed that resting energy expenditure increases in patients with newly diagnosed tumors, which is related to C-reactive protein and release of inflammatory cytokines. After eflfectjve therapy,resting energy expenditure decreases in some degree.In addition,the stage and differentiation of tumors also affect metabolism.However,there are some conflicts among research findings.The characteristics of energy metabolism and influential factors in patients with tumors are reviewed in this paper.

Objective To investigate the value of transvaginal ultrasound in the diagnosis of endometrial polyps. Methods One hundred and ten patients diagnosed as endometrial polyps by transvaginal ultrasound and undergone operative hysteroscopy and histologic examination, were analyzed retrospectively.Results Among 110 cases 75 cases (68.2%) were accurately diagnosed by transvaginal ultrasound,while 35 cases (31.8%) were misdiagnosed.The diseases misdiagnosed included endometrium hyperplasia,intrauterine adhesions and submucousmyoma.Conclusions Combining clinical symptoms with ultrasonogram characters and optimal time of detection can reduce the misdiagnostic rate of endometrial polyps.

Respiratory viral infections are the most common cause of infantile wheezing, as well as one of the major inducents of acute exacebarbations of chronic childhood asthma. Recent studies focus on the mechanism of virus-induced airway inflammatory response which is still not completely clear. Many new pathophysiologic mechanisms such as epigenetics are advanced to explain the association between viral respiratory infections and asthma attack. In the present reports, recent data on the role of early-life viral infections in the development and progression of childhood asthma are reviewed.

Parenteral nutrition associated cholestasis (PNAC) mainly occurs in children. Currently identified risk factors include premature infants, lack of enteral feeding, repeated infections, and toxicity or nutrient deficiency of parenteral nutrition solution. Recent studies have shown that nuclear receptor-mediated bile acid transporter may be the key site of PNAC pathogenesis, in which some cytokines play important roles. New anti-cholestatic therapy based on the regulation of expression of these molecules may prevent end-stage liver disease caused by PNAC.