OBJECTIVE：To study the enhancement effect of dipentene in the transdermal absorption of tinidazole.METHODS:In vitro,by means of traditional method to compare the enhancement effect of dipentene with azone at difference concentrations in the transdermal absorption of tinidazole.RESULTS:andCONCLUSION:It was showed that various concentrations of transdermal enhancers could promote absorption of tinidazole in different degrees and 4% Azone and 3%dipentene were the most effective.

OBJECTIVETo evaluate the usefulness of two- dimensional (2D) and three-dimensional (3D) computed tomography (CT) in the identification and classification of Le Fort type fractures.

METHODSSixty-two patients with different types of Le Fort fractures underwent CT scanning and 3D-CT reconstruction. The data were analyzed by multiplanar reconstruction (MPR), surface shaded display (SSD) and volume rendering (VR) respectively.

RESULTSThe patients with Le Fort I, Le Fort II fracture and Le Fort III fracture accounted for 16.1%, 14.5% and 12.9% respectively. The compound fractures were the most common type and accounted for 56.5% (n=35, 18 cases with Le Fort I+II fracture, 10 cases with Le Fort II+III fracture and 7 cases with Le Fort I+ II+III fracture). Fifty-five cases coexisted with other fractures in maxillofacial region. 2D-CT could be used to define the tiny fractures and the deep-structure fractures more accurately compared with 3D-CT, but the real impression of Le Fort type fractures could not be correctly evaluated on 2D-CT. 3D-CT could clearly demonstrate the whole shape of Le Fort type fractures and identify the classification of Le Fort fractures.

CONCLUSIONS3D-CT is the best imaging method for the diagnosis of Le Fort type fractures and can provide valuable information of space relationship, especially for the design of treatment plan before operation.

Adolescent ; Adult ; Facial Bones ; diagnostic imaging ; injuries ; Female ; Humans ; Image Processing, Computer-Assisted ; Imaging, Three-Dimensional ; Male ; Middle Aged ; Retrospective Studies ; Skull Fractures ; classification ; diagnostic imaging ; Tomography, X-Ray Computed ; methods