1.To Construct the Characteristic Elective System for Medical University
Jie HU ; Xiaoyun YANG ; Hongai YANG ; Lina WANG ; Wanzhen SHEN
Chinese Journal of Medical Education Research 2006;0(07):-
Electives,as an important component of medical education,are useful for students in expanding knowledge scope,improving knowledge structure and increasing overall capacity.Adjusting course resources,strengthening education administration and conducting course evaluation can achieve the establishment of electives system in medical colleges and universities.As a result,the electives system will contribute to the formation of inter-disciplinary medical talents.
2.Taking advantage of and developing living-related kidney transplantation
Wanzhen XU ; Huijing YANG ; Jingping SU ; Chenghong YIN
International Journal of Surgery 2009;36(4):264-266
Kidney transplantation has become the optimal treatment for end-stage renal disease. However, the demand for kidney exceeds the available supply. In last years, living-related kidney transplantation has progressively increased because of the less rejection, the higher achievement ratio and so on. From 2007 to 2008 ,our hospital succeed in 196 living-related kidney transplantation based on the previous work.
3.Preparation of Magnetic Imprinted Polymer by Surface Grafting and Its Recognition Performance for Dibutyl Phthalate
Wanzhen XU ; Xiaoming ZHANG ; Weihong HUANG ; Yijing NIE ; Wenming YANG
Chinese Journal of Analytical Chemistry 2017;45(4):521-528
The magnetic molecularly imprinted polymers (MMIPs), based on the surface of magnetic nanoparticles being modified by surface grafting, have been successfully synthesized, with dibutyl phthalate (DBP) as template molecule, ethylene glycol dimethacrylate (EGDMA) as cross-linking agent and azobisisobutyronitrile (AIBN) as initiator. Scanning electron microscopy (SEM), transmission electron microscope (TEM), and elemental analysis were employed to characterize the MMIPs. The structure and magnetic properties of the MMIPs were investigated by means of X-ray diffraction and vibrating sample magnetometer. The BET surface area shows that MMIPs is 380 m2/g and MNIPs is 324 m2/g. A series of static adsorption experiments were conducted to analyze its adsorption performance, which followed pseudo-second-order model by the kinetic analysis with correlation coefficient (R2) 0.9797, and Sips equation with correlation coefficient (R2) 0.999 by the isothermal analysis. The imprinting factors of diallyl phthalate (DAP), DBP and di-2-ethylhexyl phthalate (DEHP) were 1.53, 2.21 and 1.39 respectively, showing that MMIPs had better recognition performance for DBP. The experiment of regeneration recycles with five times showed the regeneration ability of DBP was only reduced by 12.3%.
4.Influence of psychological nursing intervention on rehabilitation of children with primary nocturnal ensuresis
Liping ZHU ; Huabin YANG ; Yan GAO ; Huiying DENG ; Sihui YANG ; Yuru LIAO ; Weiping ZHANG ; Wanzhen DENG
Chinese Journal of Practical Nursing 2009;25(31):4-5
Objective In order to know the influence of psychological nursing intervention on rehabilitation of children with primary nocturnal ensuresis. Methods Divided 112 children with primary nocturnal ensuresis into the research group (40 cases) and the control group (72 cases). Routine treatment and nursing cares were used in the control group, while the psychological nursing was used in the research group in addition. Compared the treatment effect betweent the two groups. Results The efficient rate in the research group was 90.0%, which higher than that of in the control group significantly. Conclusions Psychological nursing intervention can effective promote the rehabilitation for children with primary nocturnal ensuresis.
5.Investigations and Practices on Quality Control for Undergraduate Teaching in the Medical University
Hongai YANG ; Lianhong LI ; Qiaoli CUI ; Xiaoyun YANG ; Wanzhen SHEN ; Zhihong LI
Chinese Journal of Medical Education Research 2006;0(11):-
The quality control for undergraduate teaching is an essential factor for a university toward the success;therefore uni-versities put the control as first priority among other conventional works.This study is trying to elucidate the most important com-ponents in the quality control system from different points of view including human sources and educational process.Some suc-cessful planning and practice on the quality control in our university in past decade has been summarized and discussed in this study.
6.Analysis of the HLA match rate of 222 living-related donors for kidney transplantation
Wanzhen XU ; Baoxiang JIA ; Huijing YANG ; Jingping SU ; Weiran MA ; Chenghong YIN
International Journal of Surgery 2011;38(1):25-27
Objective To study the HLA match rate of 222 living-related donors for kidney transplantation, and to give suggestions for clinical selection of suitable donors and recipients. Methods We analyzed the HLA match rate of 222 kidney transplantations from living relative donors from April 2006 to December 2008. There were 168 male recipients and 54 female recipients. The ages of 222 recipients ranged from 10 to 58. There were 133 male donors and 89 female donors. The ages of 222 recipients ranged from 21 to 64.Results The HLA-A, B, DR, DR, antigens of 87 kidney transplantations from living parental donors were half-matched, of which 14 were higher than half-matched. The HLA-A, B, DR, DQ antigens of 7 kidney transplantations from living children donors were half-matched, including 2 cases higher than half-matched.Among 56 kidney transplantations from living sibling donors, 12 cases were totally mated, 34 cases were half-matched, and the rest were less than half-matched or mismatched. Among 72 kidney transplantations from other living relative donors, 20 cases were higher than half-matched and 5 cases were completely mismatched. More than 4 HLA antigens in 6 cases were matched, but not half-matched. Three HLA antigens or less were matched in 41 cases. Conclusion The HLA match rates from living parental, children, or sibling donors were higher than other relative donors.
7.AIDS Combinated with Penicilliosis Marneffei and Malignant Lymphoma:the First Case Report
Wanzhen LIAO ; Weihua PENG ; Xuefei HU ; Aidi SUN ; Yang YU ; Jianchun LI
Chinese Journal of Nosocomiology 2006;0(07):-
OBJECTIVE To master the pathogenic conditions,clinical characteristic,and diagnostic clues about AIDS combinated with penicilliosis marneffei and malignant lymphoma.METHODS The clinical data about AIDS combinated with penicilliosis marneffei and malignant lymphoma were summarized in order to learn by experience.RESULTS The clinical symptoms of AIDS combinated with penicilliosis marneffei and malignant lymphoma could be unique,but most were various,the primary symptoms were always fever and enlargement of liver and spleen.CONCLUSIONS AIDS combinated with penicilliosis marneffei is common to be seen,but with penicilliosis marneffei and malignant lymphoma are rarely seen in the clinics,which should be taken high attention.
8.Drug-susceptibility and Results Analysis of Clinical Isolated Escherichia coli
Kaisen CHEN ; Huaguo YUAN ; Wanzhen LIAO ; Weihua PENG ; Xuefei HU ; Yang YU
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To explore the drug-resistant situation of clinical isolated Escherichia coli in our hospital from Jun to Dec in 2007,the aim is to offer evidence for drug-resistant monitoring and clinical antibiotics usage in our hospital. METHODS All clinical specimens isolated and cultured from patients were identified by using the automatic microorganism analyzer VITEK-2 as well as bacteria's drug susceptibility tests were performed using counterparts panel. RESULTS A total of 352 strains E. coli were isolated. The isolated ratio of extended spectram-?-lactamases (ESBLs) producing E. coli was 66.2% (233/352),no ESBLs producing E. coli was 33.8% (119/352). From them 111 strains E. coli were isolated in sputum and 89 strains were ESBLs producing and 22 strains were no ESBLs producing; 111 strains E. coli were isolated in urine and 62 strains were ESBLs producing and 49 strains were no ESBLs producing. The drug-resistance difference was obvious between them as well as between strains isolated from different sites. Better to select piperacillin/tazobactam,cefotetan,ertapenem,imipenem,amikacin,and nitrofurantoin to cure all isolated E. coli infection.CONCLUSIONS The drug-resistance of ESBLs producing E. coli is severe (66.2%) so that hospital administers should strengthen antibiotics usage management and improve antibiotics rational usage,inorder to decrease occurrance of bacterial resistance.
9.Diffusion of innovations theory in promoting the knowledge and technology for birth defects prevention
Wanzhen CHEN ; Jing YANG ; Guojing WANG ; Zhengyan ZHAO ; Chonggao HU ; Huimin YU ; Qiang SHU ; Wenjun SHI ; Ling QIU ; Ping YI ; Shasha HU
Chinese Journal of Hospital Administration 2012;28(5):380-383
Determining the approach to spread the knowledge and technology for preventing birth defects using the diffusion of innovations theory.Identifying the target group,orientation messages and promotion guidelines based on related literature,laws and clinical epidemiology studies.Pathways integrating both inter-personal communication and IT have pushed the adoption percentage of innovative knowledge for preventing birth defects up from 0% to 97 % in almost no time,helping the region ranking the first in China.The innovation diffusion model has caught attention of both the government and all the community.Prevention measures against birth defects are accepted community wide,while medical workers are regulated by law in their behaviors of mothers and children healthcare services to set a model for prevention of other diseases.
10.Establishment of an modified animal model of radionecrosis of the jaws in the short term and dynamic observation of clinical, pathological and imaging features
Jie LI ; Xiangbo KONG ; Yang LIU ; Xueying CHEN ; Wanzhen ZHONG ; Silian FANG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2018;25(3):115-119
OBJECTIVE To establish an modified model of osteonecrosis in the rat and observe the clinical, pathological and imaging manifestations dynamically. METHODS Healthy male SD rats were divided into 5 groups randomly, including the control group (N, 8 rats), and radiation groups (a, b, c and d, 6 rats each group). For radiation groups, the left mandible of each rat was irradiated at doses of 7.0 Gy for 5 fractions, other rats were sham irradiated, serving as control groups.7 days after irradiation, the left mandibular molars of all rats were extracted. The radiation groups rats were sacrificed at 7, 14, 21, 28 days after irradiation randomly, the 2 rats in control group were sacrificed respectively. All the rats' mandibles were taken and examined by clinical manifestation and Micro-CT and histology methods. The data was analyzed with SPSS 18.0 software package. RESULTS In clinical observation, ulcers were seen in the irradiated site at the 7th day, after then, alopecia, occlusion disorder, and pus discharged from buccal side were seen. Weight loss rightly after radiation and weight gain were seen at the 14th day. In pathological observation, marrow cavity changed first. Many adipose cell was first seen at the 7th day, and inflammations, necrosis, and fibrosis were found in medulla in the irradiated groups after that. Significant increment of empty lacunae and decrement of osteocytes were observed in all irradiated groups at the 7th day. Necrotic bone of the irradiated mandible was only found at the 28th day. Lack of new bone formation within the socket was seen in the Micro-CT three-dimensional at 28th day, and there are no more changes at the early-stage in this model. CONCLUSION An modified rat model of osteoradionecrosis was successfully established, which can shorten experimental period, and this model early stage and deserved to be further researched. Can be used to observe clinical, pathological and imaging magnification, which play a basic role in the protection in early stage and deserved to be further researched.