Objective To investigate the cyclical changes of the apparent diffusion coefficient (ADC) values of the normal uterine zonal structures and explore physiological mechanism and clinical significance of the changes .Methods Nineteen healthy young fe‐male volunteers were selected to receive DWI (b=0 and 1 000 s/mm2 ) scan during periovulatory ,late secretory and menstrual pha‐ses .The ADC values of endometrium ,junctional zone and myometrium were measured and the differences of the ADC values were analyzed .Results The ADC values among three structures were significantly different in three phases (P< 0 .05) .The ADC value of myometrium was highest and the second was endometrium and the last was junctional zone .The differences of specific uterine zonal structures in different phases were statistically significant (F=55 .674 ,P<0 .05) .There was a interaction effect between menstrual cycle and uterine structures .Conclusion The effect of zones and different phases of the menstrual cycle in young women on ADC val‐ues of uterine structures should be considered when use ADC values to diagnose uterine diseases .

Objective ToevaluatethereportingqualityofChineseimagingdiagnosticaccuracystudiesbyStandardsforReporting DiagnosticAccuracyStudies (STARD)2015.Methods AticalspublishedinChina,whichoriginatedfrom ChinaBiology Medicine (CBM),ChinaNationalKnowledgeInfrastructure(CNKI)andWanfangDatabasefromJanuary12014toApril82016wereretrievedfor statisticalanalysis.Keywordswereasfollows:"Ultrasound","CT","MRI","X-ray"and"diagnosticstudy".Tworeviewersindependently screenedtheliteraturesandassessedtheincorporatedstudies.Excel2016wasusedtofigureouttheaccordancerateandSPSS (version 17.0)wasusedtoanalyzethedata.Results 152studieswerefinallyincluded.Thenumberandproportionofstudiesonimagingdiagnostic methodswere84 (55.26%)ultrasound,29 (19.08%)CT,16 (10.53%)MRI,and23 (15.13%)withthecombinationoftwoand moremethods.Thecoincidencerateandcorrespondingnumberofsingledocumentreportswereasfollows:0%－10%,1report;11%－20%,4reports;21%－30%,45reports;31%－40%,74reports;41%－50%,24reports;51%－60%,3reports;and61%－70%,1 report.Therewasnosignificantdifferenceofcoincidencerate (P＝0.09)betweendifferentimagingdiagnosticmethods.Also,there wasnosignificantdifferenceofcoincidenceratebetweentheoldentriesinSTARD2003andnewentriesinSTARD2015(P＝0.34). Conclusion ThisstudyprovidesareferencebaselinefortheresearchersandthecliniciansonthequalityofChinesetestreportson imagingdiagnosticaccuracy.Itisshowedthat,thereportsondiagnosticaccuracyofUltrasound,CT,MRIandX-raypublishedbetween January1,2014andApril8,2016aregenerally middleandlow level.

BACKGROUND AND PURPOSE: Whether or not migraine can cause cumulative brain alterations due to frequent migraine-related nociceptive input in patients is largely unclear. The aim of this study was to characterize longitudinal changes in brain activity between repeated observations within a short time interval in a group of female migraine patients, using resting-state functional magnetic resonance imaging. METHODS: Nineteen patients and 20 healthy controls (HC) participated in the study. Regional homogeneity (ReHo) and functional interregional connectivity were assessed to determine the focal and global features of brain dysfunction in migraine. The relationship between changes in headache parameters and longitudinal brain alterations were also investigated. RESULTS: All patients reported that their headache activity increased over time. Abnormal ReHo changes in the patient group relative to the HC were found in the putamen, orbitofrontal cortex, secondary somatosensory cortex, brainstem, and thalamus. Moreover, these brain regions exhibited longitudinal ReHo changes at the 6-week follow-up examination. These headache activity changes were accompanied by disproportionately dysfunctional connectivity in the putamen in the migraine patients, as revealed by functional connectivity analysis, suggesting that the putamen plays an important role in integrating diverse information among other migraine-related brain regions. CONCLUSIONS: The results obtained in this study suggest that progressive brain aberrations in migraine progress as a result of increased headache attacks.
Brain Stem ; Brain* ; Female ; Follow-Up Studies ; Headache ; Humans ; Longitudinal Studies* ; Magnetic Resonance Imaging ; Migraine Disorders* ; Putamen ; Somatosensory Cortex ; Thalamus

BACKGROUND/AIMS: Increasing evidence shows involvement of psychological disorders in functional dyspepsia (FD), but how psychological factors exert their influences upon FD remains largely unclear. The purpose of the present study was to explore the brain-based correlations of psychological factors and FD. METHODS: Based on Fluorine-18-deoxyglucose positron emission tomography-computed tomography, the altered cerebral glycometabolism was investigated in 40 FD patients compared with 20 healthy controls during resting state using statistical parametric mapping software. RESULTS: FD patients exhibited increased glucose metabolism in multiple regions relative to controls (P < 0.001, family-wise error corrected). After controlling for the dyspeptic symptoms, increased aberrations persisted within the insula, anterior cingulate cortex (ACC), middle cingulate cortex (MCC) and middle frontal cortex (midFC), which was related to anxiety and depression score. Interestingly, FD patients without anxiety/depression symptoms also showed increased glycometabolism within the insula, ACC, MCC and midFC. Moreover, FD patients with anxiety/depression symptoms exhibited more significant hypermetabolism within the above 4 sites compared with patients without anxiety/depression symptoms. CONCLUSIONS: Our results suggested that the altered cerebral glycometabolism may be in a vicious cycle of psychological vulnerabilities and increased gastrointestinal symptoms.
Anxiety ; Cerebral Cortex ; Depression ; Dyspepsia* ; Electrons ; Glucose ; Gyrus Cinguli ; Humans ; Metabolism ; Psychology*