1.The effects of self-value on personality
Chinese Journal of Tissue Engineering Research 2002;6(19):2983-
This article try to illustrate the relationship of self value and personality by paraphrasing these two concepts,and deduce the effects of self value to personality from this.This article also point out the questions how to direct and help university students to set proper self value and then modle healthy personality.It bring forward supposition of the resolvement of the questions.On the base of the demonstrative research we carry out a validative research.
2.Diagnostic value of point-of-care lung ultrasonography
Chinese Pediatric Emergency Medicine 2015;22(6):375-378,382
Lung ultrasound(LUS)has gained increasing popularity among intensivists in recent dec-ades.Although limited by the presence of air,LUS has proved to be useful in the evaluation of a number of different acute and chronic conditions,such as pneumonia,pneumothorax,acute lung injury,alveolar-intersti-tial syndrome,pleural effusion,etc,and showed a relatively higher sensitivity,specificity and diagnostic accu-racy compared to routine radiographic imaging.It is also critical in improving the safety of pleural interven-tional procedures.The most common signs for diagnosing and differential diagnosing include the pleural line, lung sliding,the A-line,the quad sign,the sinusoid sign,the fractal,and tissue-like sign,the B-line,lung rock-ets,abolished lung sliding with the barcode sign,the lung point,the dynamic air bronchogram,etc.The BLUE-protocol allows differential diagnosis of acute respiratory failure.LUS is a feasible technique that can be used routinely and integrated into clinical practice in the fields of intensive care,emergency care,respirato-ry and general medicine.
3.Investigation on the Perception of Surgeon to ADR Reporting System
Guiming WANG ; Haoliang ZHAO ; Ying ZHAO
China Pharmacy 2005;0(17):-
OBJECTIVE: To investigate the perception of surgeon to ADR reporting system. METHODS: Postal questionnaire was used for survey among 300 surgeons in November 2009. RESULTS & CONCLUSIONS: Surgeons mastered a little knowledge about ADR reporting system. More than 50% of surgeons took one-side view on national ADR monitoring with ADR reporting rate of 42.8%. 57.2% of surgeons hadn’t received relevant training. It is suggested that surgeons receive training and education about the knowledge of ADR reporting.
5.Clinical observation of therapeutic efficacy of insulin sensitizer in treatment of newly-diagnosed type 2 diabetes
Shufang WANG ; Xiaohong QU ; Ying ZHAO
Chinese Journal of Diabetes 2006;14(6):415-416
In observing the therapeutic efficacy of insulin sensitizer in treatment of early T2DM,120 T2DM patients were randomly divided into 3 groups: group A received 4 mg rosiglitazone daily;group B received 1.5 g metformin daily;group C received 4 mg rosiglitazone and 1.0 g met-formin every day.Before and after the treatment,fasting glucose,HbA1c,weight,adiponectin,BMI and HOMA-IR were measured or calculated.We found that fasting glucose,HbA1c and HOMA-IR of 3 groups were obviously decreased in comparison with their baseline and adiponectin was significantly increased.In conclusion,insulin sensitizer can obviously decrease the levels of glucose,HbA1c and HOMA-IR,and increase the level of serum adiponectin in T2DM.Insulin sensitizer in combination of metformin is suitable for treatment of T2DM.
6.Role of Nrf2 in neurodegenerative diseases and recent progress of its activators.
Chunyang ZHAO ; Xiaoliang WANG ; Ying PENG
Acta Pharmaceutica Sinica 2015;50(4):375-84
The nuclear factor erythroid 2 related factor 2 (Nrf2) is a key protein of endogenous antioxidant defense systems in the body. In response to oxidative stress, Nrf2 translocates to nucleus and binds to antioxidant response elements (ARE), regulating the expression of a large amounts of antioxidant genes and maintaining a proper redox balance. The pathological processes of neurodegenerative diseases are associated with generation of reactive oxygen species, which cause oxidative stress. Oxidative stress plays a cardinal role in the onset and progression of neurodegenerative diseases. Nrf2-inducer compounds can reduce oxidant stress and have shown therapeutic efficacy in many neurodegenerative disease models. How to activate the Nrf2 signaling pathway effectively has been received much attention. Here we provided an overview of specific mechanism of Nrf2-ARE pathway and the protective effects of Nrf2 in different neurodegenerative diseases, and summarized the Nrf2 activators recently in preclinical study.
7.Diagnostic value of distal subc(i)avian artery flow velocity tracing for proximal segment severe stenosis
Jingping WU ; Ying WANG ; Yuzhen ZHAO
Chinese Journal of Ultrasonography 2013;22(10):857-860
Objective To discuss the diagnostic value of distal subclavian artery flow velocity tracing for proximal segment severe stenosis.Methods 56 cases with 112 subclavian arteries were examed by ultrasonography and multidetector CT angiography respectively,then the flow velocity tracing of distal subclavian arteries had been compared with CT results.Results In all 112 subclavian arteries,there were 37without proximal segment stenosis,32 with mild stenosis,12 with moderate stenosis,and 31 with severe stenosis.Innominate arteries and other parts of subclavian arteries had no stenosis.In diagnosis of subclavian artery proximal severe stenosis using single phase single peak waveform,the sensitivity,specificity,positive likelihood ratio,and negative likelihood ratio were 83.9 %,96.3 %,22.7,0.063 respectively.The sensitivity,specificity,positive likelihood ratio,and negative likelihood ratio were 100 %,93.8 %,16.1,0 respectively,in terms of diagnosis by application of acceleration time ≥0.11s.Conclusions The statistics of acceleration time ≥0.11 s and single phase single peak waveform have high application value in diagnosis of subclavian artery severe stenosis respectively.
8.Study on the protection of Yufeng Capsule on activity of ATPase in brain tissue of rat with ischemia-reperfusion
Ying ZHAO ; Zhongren SUN ; Wei WANG ;
Chinese Traditional Patent Medicine 1992;0(08):-
Objective: To observe the effect of Yufeng Capsule (Radix Astragali, Radix Salviae Mitiorrhizae, Rhizoma Gastrodiae, etc) on the moisture content, activity of Na +,K + AT Pase and Ca 2+ ATPase in brain tissue of rat with ischemia reperfusion.Methods:the model with ischemia reperfusion was established by line embolism method, the moisture content and activity of ATPase in brain tissue of model rat were determined respectively at ischemia 2h reperfusion 1h and ischemia 2h reperfusion 24h.Results:Yufeng Capsule could significantly decrease moisture content of rats brain, increase the activity of Na +,K + ATPase and Ca 2+ ATPase.Conclusion:Yufeng Capsule could prevent and treat the cerebral edema caused by ischemia reperfusion, its mechanism may be related to improving cytomembrane ionic transport after ischemia reperfusion.
9."An apoptotic ""Eat Me"" signal: phosphatidylserine exposure"
Lin ZHANG ; Ying ZHAO ; Che WANG
Chinese Journal of Biochemical Pharmaceutics 2017;37(3):320-322
Phosphatidylserine (PS) is a phospholipid that is abundant in eukaryotic plasma membranes,has crucial biological functions.Under cell apoptosis, cells can not generate enough ATP for energy and the concentration of cytoplasmic Ca 2 +increases, resulting in PS eversion.Apoptosis and the clearance of apoptotic cells are essential processes in animal development and homeostasis.For apoptotic cells to be cleared, they must display aneat me signal, most likely PS exposure, which prompts phagocytes to engulf the cells.PS is exposed by the action of scramblase on the cell's surface in biological processes such as apoptosis and platelet activation.Once exposed to the cell surface, PS acts as an eat me signal on dead cells, and creates a scaffold for blood-clotting factors on activated platelets.The molecular identities of the flippase and scramblase that work at plasma membranes have long eluded researchers.Indeed, their identity as well as the mechanism of the PS exposure to the cell surface has only recently been revealed.We describe how PS is exposed in activated platelets and in apoptotic cells, and discuss the clearance of apoptotic cells.
10.Research of the Evaluation Model of Hospital Beds Utilization Efficiency Based on the Single Bed Work Efficiency
Ying LIU ; Jingtong WANG ; Yue ZHAO
Chinese Hospital Management 2017;37(4):35-37
Objective To investigate the application and feasibility of the single bed work efficiency in the evaluation of hospital beds efficiency,to establish the hospital beds efficiency evaluation model,in order to provide the basis for scientific and effective utilization and evaluation of beds.Methods Proposing the concept of single bed work efficiency,establishing a new evaluation model of bed efficiency,and analyzing the utilization of hospital beds in 2015.Results Single bed work efficiency is supenor to other indexes in evaluating the Utilization efficiency of hospital beds,and the new bed efficiency evaluation model is more objective and accurate.Conclusion The evaluation model of hospital beds utilization efficiency based on the single bed work efficiency is more comparable and operable,which can be widely used in hos pital delicacy management.