1.Professor Zhang Peiying's Experience in Treatment Unstable Angina of Coronary Heart Disease
Journal of Zhejiang Chinese Medical University 2014;(7):865-867
Objective This paper sums up professor Zhang Peiying's clinical experience in diagnosing and treating unstable angina(UA) of coronary heart disease. [Methods]Generalizing the pathogenesis, rules of treatment and principle of diagnosis about UA, through the reference of classical theory of Traditional Chinese medicine and clinical observation. Then analyse professor Zhang Peiying's characteristics about diagnosing and treating UA by two examples of medical record.[Results]Professor Zhang considers deficiency of Qi and stagnation of phlegm is the premise and foundation of UA, holds that stagnation of phlegm, stagnation of blood and spasm of heart vessel are the key causes of the disease and removing blood stasis, relieving spasm of vessel, strengthening the spleen and reducing phlegm is the basic treatment principle. He divides UA into 4 categories: stagnation of heart blood syndrome, stagnation of phlegm and blood syndrome, deficiency of Qi and stagnation of blood syndrome,weakness of Yang with stagnation of phlegm and blood. [Conclusions]Professor Zhang Peiying's scholar thought and clinical experience in diagnosing and treating UA of coronary heart disease is effective. His thought and clinical experience are worth extending and applying.
2.Study on the Levels of Cytokines in Sera of Patients with Various Types of Psoriasis
Liangfen ZHANG ; Qinxue WU ; Qun WANG
Chinese Journal of Dermatology 2001;34(2):101-102
Objective To investigate the levels of cytokines in sera of patients with various types of psoriasis.Methods Six cytokines, sIL-2R、 IL-2、 -4、 -10、 -12 and IFN-γ , were detected by sandwich ELISA in the sera from 15 patients with guttate psoriasis, 23 plaque psoriasis, 9 pustular psoriasis, 9 arthropathic psoriasis and 9 erythrodermic psoriasis.Results Significantly higher levels of cytokines were observed in guttate psoriasis for sIL-2R (P<0.01), in plaque psoriasis for IL-4,-12 and sIL-2R (P< 0.05 or < 0.01), in pustular psoriasis for IL-4 and -10 (P< 0.05), in arthropathic psoriasis for IL-10 (P< 0.01), in comparison with the controls.The levels of the six cytokines were increased in erythrodermic psoriasis with no significant difference from the controls.The ratio of the average level of IL-4 to IFN-γ was 1.57 in pustular psoriasis, 0.61 in plaque psoriasis, 0.30 in gutatte psoriasis, 0.24 in erythrodermic psoriasis, and 0.02 in arthropathic psoriasis.Conclusion There is different expression of cytokines in sera of patients with various types of psoriasis.
3.Efficacy of escitalopram in acute schizophrenia and depression and its influence on blood parameters with disease
Qun ZHANG ; Xiaojun WANG ; Shuwen DU
Chinese Journal of Biochemical Pharmaceutics 2017;37(2):223-225
Objective To analyze the application effect of escitalopram in the patients with acute schizophrenia with depression and influence situation for the disease related blood indexes.Methods 84 patients with acute schizophrenia with depression in our hospital from February 2015 to August 2016 were selected as the study object, and they were randomly divided into control group(conventional treatment group)42 cases and observation group( conventional treatment and escitalopram group ) 42 cases, then the total effective rates, plasma free amino acids and stress hormones indexes before and after the treatment of two groups were compared.Results The total effective rates of observation group at different time after the treatment were all higher than those of control group, the difference was statistically significant (P<0.05), the plasma free amino acids after the treatment were all higher than those of control group, the difference was statistically significant (P<0.05), serum stress hormones were all lower than those of control group, the difference was statistically significant (P<0.05), the differences of two groups were all significant.Conclusion The application effect of escitalopram in the patients with acute schizophrenia with depression is better, and it also has active improvement role for the disease related blood indexes of patients.
4.Study on the Levels of Cytokines in Sera of Patients with Various Types of Psori asis
Liangfen ZHANG ; Qinxue WU ; Qun WANG
Chinese Journal of Dermatology 1994;0(02):-
Objective To investigate the levels of cytokines in sera of patien ts with various types of psoriasis. Methods Six cytokines, sIL-2R、 IL-2、- 4、-10、-12 and IFN-? , were detected by sandwich ELISA in the sera from 15 patients with guttate psoriasis, 23 plaque psoriasis, 9 pustular psoriasis, 9 arthropathic psoriasis and 9 erythrodermic psoriasis. Results Significantly hig her levels of cytokines were observed in guttate psoriasis for sIL-2R (P
5.Time course and neural basis of early visual perception for facial emotions
Xiaoyan LIAO ; Qun WANG ; Xiaoyuan ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(11):1046-1050
The complex multidimensional visual patterns of facial expression is particularly well sui ted for studying perception and the processes underlying perceptual integration of component parts into a meaningful whole.With the high resolution in milliseconds,event-related potential (ERP) may be an excellent technique to track the time course of cognitive processing for facial emotions.Facial affective stimuli elicit particular ERP components involved in early processing of facial expressions,including:early sensory processing of visual stimuli:the P100;early structural encoding of facial features:the N170;second-order sustained activities necessary for consequent deeper processing:the posterior P2 and decoding of facial features to identify emotional content:the N250.We reviewed above mentioned ERP components respectively,in order to add the knowledge about ERP components as indicators of neural dynamics of facial emotion processing,and to provide a point of reference for further exploration on facial emotion processing that may be useful for understanding human cognition development and pathology.
6.Ultrasonographic assessment of fetal cardiovascular function in selective intrauterine growth restriction
Xing ZHANG ; Huishen WANG ; Qun FANG
Chinese Journal of Applied Clinical Pediatrics 2015;(13):996-999
Objective To evaluate the fetal cardiovascular function in selective intrauterine growth restriction (sIUGR)in monochorionic diamniotic(MCDA)twins by using 2D and color Doppler ultrasonography. Methods Twenty - four sIUGR pregnancies and 20 normal MCDA twins pregnancies were enrolled at the First Affiliated Hospital of Sun Yat - Sen University from December 2013 to September 2014,and cardiac structure of fetus and Doppler patterns of the umbilical artery(UA),umbilical vein(UV),pulsatility index of ductus venosus(DV - PI),atrioventricular valve, semilunar valve,tricuspid annulus systolic displacement(TAPSE),fractional shortening of left ventricle short axis(FS) and myocardial performance index(Tei index)of both ventricles were assessed. Results Cardiothoracic ratio,heart rate,DV - PI,FS,TAPSE,Tei index of the left ventricle(0. 34 ± 0. 03,0. 34 ± 0. 04),Tei index of the right ventricle (0. 35 ± 0. 03,0. 35 ± 0. 03)were not significantly different compared with those of the normal MCDA twins(all P ﹥0. 05). Cardiothoracic ratio,ventricular wall thickness,isovolumetric relaxation time( IRT),isovolumetric contraction time(ICT),TAPSE and tricuspid regurgitation(TR)in the larger twins of sIUGR were significantly bigger than those in the smaller twins of sIUGR(all P ﹤ 0. 05),Tei index of both ventricles in the larger twin of sIUGR was significantly higher than that in the smaller twins of sIUGR(Tei index of left ventricle:0. 43 ± 0. 06 vs 0. 35 ± 0. 04,Tei index of right ventricle:0. 43 ± 0. 06 vs 0. 34 ± 0. 04,P ﹤ 0. 05),the peak E in early diastolic / the peak A in atrial contraction (E/ A),the percentage of inflow during of cardiac cycle length(inflow/ CCL)in larger twin of sIUGR were significantly lower than those in smaller twin of sIUGR(all P ﹤ 0. 05). Conclusions There was no difference of cardiac function in normal MCDA twins,at the beginning of the diagnosis of sIUGR,cardiac dysfunction were found in larger twin,follow -up examination are helpful to clinical decision.
7.Words Comprehension in Autistic Children:Based on Eyes Movement
Mei WANG ; Haicong ZHANG ; Qun ZHANG ; Yinghua WANG
Chinese Journal of Rehabilitation Theory and Practice 2016;22(3):252-256
Objective To investigate the charactoristics of comprehension of words or phrases of nouns in chidren with autism. Meth-ods From November, 2014 to April, 2015, 43 children with autism and 10 with Down's syndrome aged 7-14 years accepting special educa-tion, and other 42 normal children aged 7-8 years were asked to identify the pictures according to the words, wearing Tobii Ⅱ Glasses to re-cord eyes movement. Results The incidence of right answer was more in the normal children than in the ones with autism or Down's syn-drome (χ2>5.647, P<0.05), and more focused on the right pictures (χ2>6.248, P<0.05). For the phrases, the children with autism tended to fo-cus on the words as the order of speech, but not the center word (χ2>7.15, P<0.05). For the words, the first views after questions were differ-ent from the children with autism to the normal children (χ2>5.04, P<0.05). Conclusion Children with autism tend to focus on the words as the order of speech, but not the center word, which may influence the phrases understanding, and be influenced by the intuitive vision.
9.Determination of Arsenic and Copper in Chinese Patent Medicines by Microwave-digestion Atomic Absorption Spectrometry
Lijuan ZHANG ; Qun MA ; Jing WANG ; Xuexin GU ; Shuyan WANG
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(05):-
Objective To establish a method for the determination of arsenic and copper in Chinese patent medicines.Methods Digested by microwave,the content of arsenic in Liuwei Dihuang Pill (prepared with water and honey) was measured by sequence flowing injection-hydride generation-atomic absorption spectrometry and content of copper by flame atomic absorption spectrometry. Effects of factors,including digestion temperature,smashing granularity of samples,proportion of digestive ingredients,volume of digestive agents,digestion procedure and digestion time,on the content determination were studied.Results Recoveries of arsenic and copper were 100.8%~114.3%and 94.4%~110.2%respectively under optimum conditions.Conclusion This method is simple and effective for the content determination of heavy mental in Chinese patent medicines.
10.Biocompatiblity of various polypropylene meshes in breast ptosis correction
Zhi WANG ; Wenze WANG ; Hailin ZHANG ; Baodong SUN ; Qun QIAO
Chinese Journal of Medical Aesthetics and Cosmetology 2011;17(5):369-372
Objective Implanting surgical meshes to support breast in periareoler mammaplasty shows an excellent prospect.But shrinking of the mesh and the adhesion formation affected the postoperative shape and palpation of the breast.The aim of this study was to compare biocompatible properties of four different polypropylene meshes (Prolene(R) ; Vypro Ⅱ(R) ; Premilene Mesh (R) and Premilene Mesh LP(R)) and to discuss the inclusion criteria of meshes in this technique.Methods The study was carried out in pigs.Four different polypropylene meshes were implanted subcutaneously in belly.90 days after implantation the mesh samples were explanted,and complications,foreign-body reaction,collagen fiber and elastic fiber formation were observed,as well as ultrastructures for the biocompatible properties.Results The biocompatible properties of each mesh were different.The foreign-body reactions determined the biocompatible properties,and affected the postoperative shape greatly.Conclusions Premilene Mesh LP o as a newer low-weight polypropylene mesh,has superior properties to the others.