2.Adherence activity of periodontal pathogens and cariogenic bacteria to hydroxyapatite disks
min-feng, WANG ; de-yi, LI ; zong-lin, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(01):-
Pg.The adherence activity of periodontal pathogens to HA was enhanced by Ss and Av.When cultivated with Sm,the adherence activity of Pg was reduced.Periodontal pathogens had no effect on the adherence activity of Sm and Av,and Ss excepted. Conclusion The adherence activity of periodontal pathogens is lower than that of cariogenic bacteria.Periodontal pathogens can utilize early-attached bacteria to become those predominant bacteria in periodontal ecosystem.
3.A 1:1 Matched Case-control Study on Risk Factors for Stomach Cancer in Ganyu County
Xu-Shan WANG ; De-Lin WU ; Xiao-Feng ZHANG ;
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(05):-
Objective To explore the risk factors and protective factors for stomach cancer in Ganyu county.Methods Data of 319 pairs of new stomach cancer cases and health controls(1:1 matched)were studied by conditional Logistic regression method on the influential factors.Results The main risk factors for stomach cancer were the habits of eating hot foods(OR= 2.21,95%CI:1.57~3.12),the history of upper gastrointestinal inflammation(4.26,2.59~7.03),family history of cancer(2.29, 1.37~3.82);The main protective factors were often eating raw garlic(OR=0.64,95%CI:0.42~0.96),regular drinking tea(0.37, 0.25~0.54).Conclusion Unhealthy dietary habits,the history of upper gastrointestinal inflammation and family history of cancer are related to stomach cancer,while eating raw garlic and regular drinking tea may be effective in preventing the occurrence of stomach cancer.The results could be applied in stomach cancer prevention activities in Ganyu county.
4.A Study on the Effects of RF Coil for the Static Magnetic Field
Hong WANG ; Qing-De LIN ; Feng HUO
Chinese Journal of Medical Instrumentation 2001;25(3):139-140
In the paper, we introduce the studies on some abnormal points in static magnetic field,find out the causes and mean while, give the methods of exclusion, thus the adjustment of MRI can be made perfectly.
5.Significance of Susceptible Gene Expression Profiles in Nasal Polyposis.
Clinical and Experimental Otorhinolaryngology 2008;1(4):177-183
Nasal polyposis (NP) is a common chronic inflammatory disease of the rhinosinus mucosa and a complex disease with strong genetic and environmental components. During the past 10 to 20 yr, many studies have been performed to determine differential gene expression profiles between NP and normal nasal tissues, in order to identify susceptible genes that are associated with NP-related traits. Despite achievement in the identification of candidate genes and their associated pathogenic pathways, the large challenges remain as the genetic and molecular alterations required for its development and progression are still unclear. Therefore, the development of novel, powerful tools for gene discovery, and a closer integration of genetics and medical biology would provide valuable insight into the pathogenesis of NP.
Achievement
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Biology
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Gene Expression
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Genetic Association Studies
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Mucous Membrane
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Transcriptome
7.SOX9 expression correlates with microvascular density, progress and prognosis in gastric cancer patients.
Qian WANG ; Jin ZHANG ; Yi-fang ZHONG ; Ying CONG ; De LIN
Chinese Journal of Pathology 2012;41(12):848-849
Adenocarcinoma
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metabolism
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pathology
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surgery
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Adenocarcinoma, Papillary
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metabolism
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pathology
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surgery
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Antigens, CD
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metabolism
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Carcinoma, Signet Ring Cell
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metabolism
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pathology
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surgery
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Endoglin
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Female
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Humans
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Male
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Microvessels
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pathology
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Middle Aged
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Neoplasm Staging
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Neovascularization, Pathologic
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Receptors, Cell Surface
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metabolism
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SOX9 Transcription Factor
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metabolism
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Stomach Neoplasms
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metabolism
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pathology
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surgery
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Survival Rate
8.Analysis of monitoring results on plague's host animal and its medium insects in Quanzhou city of Fujian province between 2000 and 2009
Feng-ping, LI ; Wei-ming, WANG ; De-lin, YANG ; Qing-hu, ZHANG
Chinese Journal of Endemiology 2011;30(5):518-520
Objective To examine the composition and distribution of animal reservoir of plague in Quanzhou city, Fujian province, and so as to accumulate basic data for making the plague prevention and control measures. Methods Rodents were captured by cages in six monitoring spots of Quanzhou city between 2000 and 2009. Then rodents and flea species were identified. Rats liver and spleen homogenates were detected of plague F1 antigen by reverse indirect hemagglutination test (RIHA); rats serum were detected of plague F1 antibody by indirect hemagglutination test (IHA). ResultsA total of 26 264 rodents were captured between 2000 and 2009.Rattus norvegicus and Rattus flavipectus were dominant species, which were accounted for 45.97% (12 074/26 264)and 32.01%(8407/26 264), respectively. The account of Rattus flavipectus captured between 2005 and 2009 was (26.99 ± 2.46)% and (37.03 ± 3.79)% between 2000 and 2004. The difference was statistically significant (t =4.97, P < 0.05). Total rodent densities was (6.86 ± 1.44)%, including(5.36 ± 1.83)% in mountains and (6.81 ±1.66)% in coastal areas, respectively, and the difference was not statistically significant(t =1.01, P > 0.05). Total flea index and flea infection rate of rodents were 1.39 ± 0.34 and (35.90 ± 5.34)%, respectively. Xenopsylla Cheopis index was 1.20 and free flea index was 0.009. Flea infection rate was (32.36 ± 0.96)% between 2005 and 2009, which was lower than (39.44 ± 0.39)% between 2000 and 2004(t =2.76, P < 0.05). ConclusionsThe major rodent species found in Quanzhou city is Rattus norvegicus. Xenopsylla Cheopis is the dominant flea species.Spreading of plague among Rattus is not found.
9.Effect of extract of leave Ginkgo biloba(EGb_(50))on sciatic nerve regeneration in rats and its doseeffect relationship
Hao-Dong LIN ; Hnan WANG ; De-Song CHEN ; Ji-Feng LI ; Yu-Dong GU ;
Chinese Journal of Microsurgery 2000;0(04):-
Objective To provide the promoting effect of extract of leave Ginkgo biloba(EGb_(50))on nerve regeneration and the dose-effect relationship.Methods Sciatic nerve injury model was set up in 96 male Spraque-Daweiy rats and then randomly divided into four groups:normal saline (NS) group,the low dose EGb_(50) group (50mg?kg~(-1)?d~(-1)),the moderate dose EGb_(50) group (100 mg?kg~(-1)?d~(-1)) ,the high dose EGb_(50) group (200 mg?kg~(-1)?d~(-1)).Electrophysiological,histological examinations and functional eval- uation were used to assess nerve regeneration and the functional recovery in 2,4,6,8 weeks of operative inter- vals respectively.Results The recovery rate of sciatic functional index(SFI),tetanic tension,motor nerve conduction velocity,muscle cell cross-section area of triceps surae and the passing rate of myelinated nerve were significantly higher in EGb_(50) group in all the time point than in control(P<0.01).Except the recovery rate of sciatic functional index (SFI),there was significant difference between high dose group and moderate, low dose group.(P<0.01,P<0.05).Conclusion EGb_(50) has the effect of promoting regeneration of in- juried peripheral nerve and the high dose can get the best result.
10.Effects of different processing methods on effective components and sulfur dioxide residue in Gastrodiae Rhizoma.
Zi-Wan NING ; Chun-Qin MAO ; Tu-Lin LU ; De JI ; Jing LIU ; Lin JI ; Huan YANG ; Fa-Qin WANG
China Journal of Chinese Materia Medica 2014;39(15):2814-2818
The contents of adenosine, gastrodin, 4-hydroxybenzyl alcohol, 4-hydroxybenzaldehyde, parishin and sulfur dioxide residue were compared in differently-processed Gastrodiae Rhizoma to provide the basis for a reasonable processing method of Gastrodiae Rhizoma. The analysis was performed on a Merck Purospher STAR column (4.6 mm x 250 mm, 5 μm) with a mobile phase consisting of methanol and water (containing 0.1% formic acid) under gradient elution at a flow rate of 1.0 mL x min(-1). The eluates were detected at 270 nm, and the column temperature was 35°C. The content of adenosin, gastrodin, 4-hydroxybenzyl alcohol, 4-hydroxy-benzaldehyde and parishin in processing of boiling or sulfur-fumigated were lower than that of in processing of steaming. Furthermore, the sulfur dioxide residue of sulphur-fumigated groups exceed 400 mg x kg(-1). This stable and reliable method will contribute to the quality control of different processed Gastrodiae Rhizoma.
Drug Contamination
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Drugs, Chinese Herbal
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chemistry
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Gastrodia
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chemistry
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Sulfur Dioxide
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analysis
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Technology, Pharmaceutical
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methods