1.Curriculum reformation of rehabilitation therapy with the integrative traditional and western medicine
Lei WANG ; Zun WANG ; Yihuang GU
Chinese Journal of Medical Education Research 2011;10(9):1061-1063
Rehabilitation therapy with the integrative traditional and western medicine is the devel opment trend in China,and it is also the aim of talent education of Nanjing University of Chinese Medicine.Based on the introduction of rehabilitation therapy education in our university,this article makes a discussion on the research and practice of curriculum reformation of rehabilitation therapy with the integrative traditional and western medicine.Additionally,it puts forward some implement measures.
3.Problems and Recommendations of Community Exercise Rehabilitation for Cardiovascular Disease
Min CHAO ; Feng LIANG ; Zun WANG ; Lei WANG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(10):999-1000
Community rehabilitation of cardiovascular disease is of great significance. Exercise therapy of cardiovascular disease in communities is necessary and feasible. At present, the main problems China faced to carry out community exercise therapy of cardiovascular disease include: cardiovascular patients with a weak sense of community exercise therapy, lack of professional rehabilitation personnel, inadequate community-based exercise therapy practice and lack of community rehabilitation funding. To solve above problems, we should strengthen the community exercise therapy practice of cardiovascular disease, and promote the cooperation between community rehabilitation and hospital rehabilitation. In all, comprehensive efforts should be made in order to solve the problems.
4.Moxibustion Improved Transcutaneous Oxygen Tension and Exercise Capacity in Lower Limbs of Peripheral Arterial Disease.
Lei WANG ; Zhen-zhen GAO ; Wang ZUN ; Hua-ping PAN
Chinese Journal of Integrated Traditional and Western Medicine 2016;36(2):179-182
OBJECTIVETo observe the effects of moxibustion and treadmill exercise on transcutaneous oxygen tension and exercise capacity in lower limbs of peripheral arterial disease (PAD).
METHODSTotally 58 mild-to-moderate PAD patients were assigned to the control group (18 cases), the moxibustion group (20 cases), and the treadmill exercise group (20 cases) by random digit table. Patients in the control group received conventional drug therapy for 12 weeks. Patients in the moxibustion group and the treadmill exercise group additionally received moxibustion [at Zusanli (ST36), Sanyinjiao (SP6), Yongquan (KI1)] and treadmill exercise respectively, once per day, 5 times per week for 12 weeks in total. Ankle-Brachial Index (ABI) , transcutaneous oxygen tension (TcPO₂), 6-min walking test (6MWT), and walking impairment questionnaire (WIQ) were assessed before and after treatment.
RESULTSCompared with the control group and the same group before treatment, there was no statistical difference in ABI in the moxibustion group and the treadmill exercise group (P > 0.05). But TcPO₂, 6MWT, and WIQ were obviously elevated (P < 0.01). Besides, 6MWT and WIQ assessment of the treadmill exercise group were better than that of the moxibustion group (P < 0.01) after intervention.
CONCLUSIONMoxibustion and treadmill exercise could improve the exercise capacity and TcPO₂of lower limbers in PAD patients.
Exercise Test ; Exercise Therapy ; Exercise Tolerance ; Humans ; Lower Extremity ; physiopathology ; Moxibustion ; Oximetry ; Oxygen ; blood ; Peripheral Arterial Disease ; therapy ; Surveys and Questionnaires ; Walking
5.Relationship between pathology of concomitant exotropia medial rectus and surgical results
Zun-Jing, WANG ; Qing-Lan, KONG ; Gui-Qiu, ZHAO
International Eye Science 2009;9(5):828-830
AIM: To evaluate the relationship between the medial rectus cells counts in concomitant exotropia and surgical results. METHODS: A total of 32 pieces of medial rectus muscle were collected for HE staining in this study, of which 18 pieces were from patients with concomitant exotropia and 14 pieces were from healthy individuals. A method of strabismus score was used to assess the operative effect.RESULTS: The difference of strabismus score before and after the operation in the intermittent exotropia group was significantly higher than that in constant exotropic group (P<0.01). Under light microscope, the loosen muscle fibers and the increased stromal components in the cross sectional area of medial rectus were observed in strabismic group. The muscle cells counts was obviously lower in strabismic group than in control group (P<0.01), which was related to the difference of strabismus score before and after the operation (P<0.05).CONCLUSION: The decreased medial rectus cells counts induce concomitant exotropia directly. It is the crucial causes of the bad surgical results.
6.Relationship between normal serum uric acid levels and nonalcoholic fatty liver disease among Chinese people with normal body mass index
Zun WANG ; Dongning CHEN ; Jing CUI ; Sitong LIU
Chinese Journal of Health Management 2016;10(6):445-449
Objective Serum uric acid (SUA) levels have been identified to be associated with nonalcoholic fatty liver disease (NAFLD) which is often closely linked to obesity. However, few studies have examined the relationship between SUA levels and NAFLD in normal body mass index (BMI) people in whom NAFLD is noted not uncommon. We conducted this study to assess the association of SUA with NAFLD in Chinese normal-BMI people. Methods A total of 2 193 normal-BMI people (1 106 men and 1087 women) who participated in a health check-up were enrolled in this cross-sectional study. NAFLD was defined as a hepatic steatosis examined by liver ultrasonography in the absence of a second cause. Multiple regression analysis was performed to examine the relationship between SUA and NAFLD. Results Compared with people without NAFLD, those with NAFLD had significantly higher level of serum uric acid [males,(339.0±47.6)μmol/L vs.(309.3±53.5)μmol/L, t=3.296, P<0.01;female,(273.6±41.6)μmol/L vs. (243.9 ± 47.6)μmol/L, t=3.178, P<0.01]. Multiple regression analysis revealed that the quartile 3 and 4 of SUA in both sexes had a higher (P<0.05) odds ratio for the presence of NAFLD than the lowest quartile [males,odds ratio:2.508(1.255-3.374)and 3.383(2.058-5.490);females,odds ratio:2.186(1.090-4.384) and 2.420(1.214-4.821),respectively],after adjusting for age, body mass index, blood urea nitrogen, serum creatinine, the liver-function test, metabolic components, high sensitivity C-reactive protein, and smoking status.Conclusions Increased SUA level, even within the normal range, are independently associated with the presence of NAFLD among normal-BMI people.
7.The correlation between glucocorticoid and caries
Xiaoli WANG ; Liuqing YANG ; Zun ZHANG ; Ya GAO
Journal of Practical Stomatology 2016;32(3):397-401
Objective:To observe the changes of salivary Lysozyme (LZM),immunoglobulin A (IgA),lactate dehydrogenase (LDH),mean grey values (MGVs)of hard tissue of teeth and caries index(CSI)in patients after oral administration of glucocorticoid (GC).Methods:30 patients with oral administration of GC were included.The mixed saliva samples before and after 6 and 12 months of GC treatment were collected.LZMand IgA and LDH were examined.Surface layer panaorama films were taken and MGVs of hard tissue of teeth were measured.The decayed,missing and filled tooth(DMFT),decayed,missing and filled surface (DMFS), CSI were recorded.The same indexes were obtained from 30 age and gender matched healthy subjects as the control data.All statisti-cal analyses were performed using SPSS 17.0 software package.Results:After taking GC orally,the concentration of LZM,IgA and MGVs of hard tissue of teeth in the patients were lower than those in the controls(P <0.05),the LDH concentration,DMFT,DMFS and CSI in the patients were increased(P <0.05).In the patients the MGVs of hard tissue of teeth was negatively correlated with DM-FT,DMFS and CSI(P <0.01),LDH concentration was positively correlated with CSI(P <0.01),the concentration of LZMand IgA were negatively correlated with CSI(P <0.05).No change of the indexes was found in the controls.Conclusion:Oral administration of GC may increase DMFT,DMFS and CSI,decrease MGVs of hard tissue of teeth significantly reduce,the patients may be under higher risk of caries.
8.Risk factors for coronary artery aneurysms in children with Kawasaki disease
Zun CHEN ; Ying QIAN ; Yimei SHI ; Youcheng WANG ; Guoping JIANG
Journal of Chinese Physician 2016;18(9):1340-1344
Objective To explore risk factors for coronary artery aneurysms (CAA) in children with Kawasaki disease (KD),and reduce the rate of serious sequelae of cardiovascular diseases.Methods All the patients were diagnosed as KD in Children’s Hospital Affiliated to Medical College of Zhejiang University from January 2009 to January 2014.A total of 679 cases was included,and 42 with concurrent CAA,181 with concurrent coronary artery expansion (CAD),and 456 without coronary artery damage cases (non-coronary artery lesion,NCAL).Coronary artery damage was related to factors such as gender,age,fever,white blood cell count (WBC),hemoglobin (Hb),platelet count (PLT),erythrocyte sedimentation rate (ESR),C-reactive protein (CRP),alanine aminotransferase,serum potassium,plasma amino terminal brain natriuretic peptide precursor (NT-proBNP),and acrylic ball resistance.SPSS 18.0 software package was used for risk factor analysis.Qualitative data using chi-square test,was used to analyze the high risk factors of CAA group,and logistic multivariate regression analysis was also used.Results Chi-square test showed that male,with febrile days > 14 d,NT-proBNP ≥ 1 000 ng/L,immunoglobulin resistance was more likely to have KD concurrent CAA (P < 0.05).Multiple Logistic regression analysis showed that male [OR =4.092,95% CI (1.514,11.060),P =0.004],febrile days >14 d [OR =12.436,95% CI (4.599,33.631),P =0.000],NT-proBNP≥ 1 000 ng/L [OR =3.305,95% CI (1.401,7.794),P =0.005],and immunoglobulin resistance [OR =3.842,95 % CI (1.562,9.453),P =0.000] were independent risk factors for KD concurrent CAA.Conclusions Male children,febrile days > 14 d,NT-proBNP≥ 1 000 ng/L,and immunoglobulin resistance were independent risk factors of CAA.
9."Correlation Discussion on TCM Theory of ""Static and Dynamic Combination"" and Mechanism of Osteoblast Proliferation and Differentiation by Stress Stimulation"
Wentao ZHAO ; Xiaogang ZHANG ; Xiyun ZHAO ; Zun TONG ; Zhipeng WANG
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(9):8-10
The theory of static and dynamic combination coincides with the effect of osteoblast stress, although there are few articles on molecular biology about the theory in recent years. The treatment of static and dynamic combination theory for fractures and other orthopedic disorders is to use the localized stress fracture, and the stress controls bone formation results through afffecting proliferation of osteoblast differentiation, which has proved by relevant experimental evidence. This article discussed the molecular biology basis about the correlation between theory of static and dynamic combination and osteoblast proliferation and differentiation by stress stimulation.
10.Calcium Cytocheiuical Localization and EDX Microanalysis in Myocardial Cells
Xiaobing DU ; Yongji YANG ; Genying WANG ; Zun ZHENG
Academic Journal of Second Military Medical University 1985;0(06):-
Intracellular calcium distribution was studied in myocardial cells of mice by using pyroantimonate cytochemistry and EDX microanalysis. The results demonstrated that both OPP and PPP methods had a selective localization of intracellular bound calcium, and OPP method was more sensitive to calcium. The distribution of calcium in myocardial cells is highly departmentalized, and its mam pools were confined to sarcoplasmic reticulum and mitochondria. Calcium eylochemical localization is very useful in studying the effect of calcium in metabolism and pathogenesis of myocandial cells.