Treatment of depression is divided into drug treatment and non-drug treatment. Drug therapy including tricyclic、 tetracyclic antidepressant category、Serotonin reuptake inhibitors (SSRI)、Serotonin receptor antagonist and re-absorption inhibitors (SARI)、norepinephrine and dopamine reuptake inhibitors (NDRI)、 serotonin and norepinephrine reuptake inhibitors (SNRI)、 norepinephrine and specific serotonergic antidepressants (NaSSA) and synergist to support treatment; Non-drugs treatments include psychotherapy, electric shock therapy、transcranial magnetic stimulation (TMS) and deep brain stimulation (DBS)treatment.In clinical practice for a number of studies provide hope that patients with depression.

This paper briefly introduces some security issues in using Clinic Electronic Llinac and provides corresponding measures and suggestions,which give a reference for persons of the same occupation in security management and operation of Clinic Electronic Llinac.

Objective To investigate the factors related with final test for continued learning of rehabilitation. Methods The records of 511 continued learning students for physical therapy were analysed with linear regression, with the results of theoretical and operating test as independent variable, while sex, age, titles, profession, education, works, levels of hospital and evaluations as independent variable. Results The results of both theoretical and operating test related with profession, education, works levels and evaluation. Conclusion The models estimate the results of continued learning for rehabilitation has been established.

Acute Kidney Injury ; chemically induced ; Humans ; Paraquat ; poisoning ; Rhabdomyolysis ; chemically induced

Objective To investigate the clinical features of acute pancreatitis during pregnancy,including etiology,clinical manifestation,treatment and prognosis,in order to provided the clinical experience to prevent and treat the acute pancreatitis.Methods Retrospective analyse the clinical information of 11 patients with acute pancreatitis during pregnancy in the People's Hospital Affiliated to Peking University from January 1990 to December 2012.Results The age rage of patients was 25-34 years old.Of them,mild acute pancreatitis(MAP) was 5 cases (45.5％),while severe acute pancreatitis (SAP) were 6 cases (54.5％).Pathogenic data showed that 2 cases (18.2％) were biliary pancreatitis,7 cases (63.6％) were with hyperlipidemia,1 case(9.1％) was gallstone pancreatitis with hyperlipidemia,and 1 case (9.1％) did not find a clear cause.Five cases occurred during second trimester(45.5％),and 6 cases occurred during third trimester (54.5％) as well as no maternal death was seen.Four cases of fetal delivery were at term (36.4％),5 cases of premature delivery(45.4％),2 cases of death (18.2％),and all born infants were alive.Conclusion Acute pancreatitis during pregnancy mainly relates to biliary diseases and hyperlipidemia,and mostly occurred during third trimester.Acute pancreatitis during pregnancy can lead to premature birth,still birth.Early diagnosis and therapy are important for acute pancreatitis during pregnancy.

Radiotherapy alone and local excision combined with radiotherapy have been alternative treatments of early rectal carcinoma resection.Compared with radical surgery,both radiotherapy alone and local excision combined with radiotherapy can get satisfactory effect,and prevent the high rate of complications and adverse reactions,which will improve the quality of life for patients with rectal carcinoma and should be recommended.

Objective]To explore the relationship between Yin-wei theory and clinical practice ,and to discuss how to apply Yin-wei theory to solve practical problems in clinical situation.[Methods]We start from the Traditional Chinese Medicine(TCM) classics Nei Jing(the Canon of Internal Medicine) and Nan Jing(Canon On Eighty-One Difficult Issues),combined with Zhang Zhongjing’s application of Guizhi decoction in his book“Treatise on Febrile and Miscellaneous Diseases”to explore the cause and effect of Yin-wei theory and to comprehensively analyze its underlying thought .[Results]We found that Guizhi decoction in the“Treatise on Febrile Diseases”was not only applied in the chapter Taiyang disease,but also involved in other four chapters of Shaoyin disease and the chapter of cholera disease.In“Synopsis of Golden Chamber”,Guizhi decoction was used to treat vomitus gravidarum and affection by cold after delivery,while in Zhongjing’s practice,Guizhi decoction derived formula was widely used in the treatment of consumptive internal injuries miscellaneous disease,indicating that many internal injuries miscellaneous diseases were closely related to external infection .Tonic medicines were rarely seen alone in classical consumptive disease treatment.[Conclusion]Practice has proven that deep learning and understanding of Yin-wei theory has great guiding significance for us to put knowledge in TCM classic theories into clinical practice .Yin-wei theory opens an important window to learn“Treatise on Febrile and Miscellaneous Diseases”and trains clinical thinking,which is worth further discussion.

OBJECTIVE: To introduce the type and biological properties of medical polymer vehicle materials, and to evaluate its application in anticancer drugs. METHODS: A computer-based on-line research was performed in China Journal Full-text Database and Pubmed database published from 1990 to 2009. The key words were "polymer, anticancer drug, carrier". Articles concerning biological properties of medical polymer vehicle materials and its application in anticancer drugs were included. Meta analysis and repetitive studies were excluded. RESULTS: Quality of articles was assessed, and a total of 24 articles were included. Biological properties of medical polymer vehicle materials and its application in anticancer drugs were summarized. Medical polymer vehicle materials are novel technique with the development of pharmacological study, biomaterial study and clinical medicine. Good biocompatibility, biodegradability, regulation of degradation rate and good workability of polymer materials provided convenience and possibility for innovation of pharmaceutical preparation. Structure of drug carrier material, elevation of drug-loading efficiency, in vivo distribution, biodegradation function and effects of degradation product on bodies deserved further investigations. The study focus of anticancer drug high polymer carrier lies in the search of carrier materials with strong choice and good outcomes. CONCLUSION: Medical polymer carrier materials can control drug release speed by dosage form changes, which induced a stable drug concentration in vivo. The medical polymer carrier materials also can send drugs to a certain part of the body by release system, which cannot affect other regions in the body.

Towards the problems after the medical reform of China,such as dramatic increase of healthcare expenditure and conflict between doctor and patient,this paper analyzes the tripartite relationships between hospital,insurance supplier and patient from the theoretical and practical aspects,concludes that the non-balanced development of the current relationships is an important reason of the problems,and gives the corresponding countermeasures for reference.

Six kinds of erythemato-squamous diseases have been common skin diseases, but the diagnosis of them has always been a problem. The quantitative data processing method is not suitable for erythemato-squamous data because they are categorical qualitative data. This paper proposed a new method based on group lasso penalized classification for the feature selection and classification for erythemato-squamous data with categorical qualitative data. The first categorical data of 33 dimensions were changed by the virtual code, and then 34th dimension age data were discretized and changed by the virtual code. Then the encoded data were grouped according to class group and variable group. Lastly Group Lasso penalized classification was executed. The classified accuracy of 10-fold cross validation was 98.88% ± 0.002 3%. Compared with those of other method in the literature, this new method is simpler, and better for effect and efficiency, and has stronger interpretability and stronger stability.
Algorithms ; Computational Biology ; methods ; Humans ; Reproducibility of Results ; Skin Diseases ; classification ; diagnosis