1.Comparison of asymmetric degree between maxillofacial hard and soft tissue in facial asymmetric subjects using three-dimensional computed tomography.
Wang Sik KIM ; Ki Heon LEE ; Hyeon Shik HWANG
Korean Journal of Orthodontics 2005;35(3):163-173
The purpose of this study was to compare the asymmetric degree between maxillofacial hard and soft tissues in individuals with facial asymmetry. Computerized tomographies (CT) of 34 adults (17 male, 17 female) who had facial asymmetry were taken. The CT images were transmitted to personal computers and then reconstructed into three-dimensional (3D) images through the use of computer software. In order to evaluate the degree of facial asymmetry, 6 measurements were constructed as the hard tissue measurements while 6 counterpart measurements were taken as the soft tissue measurements. The means and standard deviations were obtained for each measurement using 3D measure, then t-test was used to investigate the differences between each hard tissue measurement and the corresponding soft tissue measurement. All measurements used in the present study showed statistically significant differences between the hard and soft tissues. The degree of soft tissue asymmetry was smaller than that of corresponding hard tissue asymmetry in case of chin deviation, frontal ramal inclination difference, and frontal corpus inclination difference. On the other hand, the degree of soft tissue asymmetry was greater than that of underlying hard tissue asymmetry in the measurement of lip canting and lip cheilion height difference. The present study suggests that asymmetric differences of hard and soft tissue is observed in facial asymmetric subjects, and thus soft tissue analysis is needed in addition to hard tissue analysis when making an evaluation of facial asymmetry.
Adult
;
Chin
;
Facial Asymmetry
;
Hand
;
Humans
;
Lip
;
Male
;
Microcomputers
2.Aortic Dissection Masquerading as Right Atrial Tumor.
Bong Kwan SEO ; Myoung Don OH ; Wang Seoung RYU ; Young Bae PARK ; Yun Shik CHOI ; Young Woo LEE ; Jae Hyung PARK
Korean Circulation Journal 1985;15(3):513-517
Aortic dissection is clinically suspected from the typical symptoms and signs and may be confirmed by computed tomography or aortography. But atypical presentations can be seen in a minority of cases, such as SVC syndrome, right pulmonary artery stenosis etc. We present a case which was initially suspected to be a right atrial tumor because of a large filling defect in the right atrium on radionuclide angiocardiography but finally confirmed to be dissection of ascending aorta by computed tomography.
Angiocardiography
;
Aorta
;
Aortography
;
Constriction, Pathologic
;
Heart Atria
;
Pulmonary Artery
3.Effects of barley and barley bran contaminated with Fusarium spp. on the growth and feed efficiency of fattening and growing pigs.
Wang Shik LEE ; Hyun June LEE ; Kwang Seok KI ; Hwan Gook NOH ; Seok Jin KANG ; Young Hun JUNG ; Kwang Soo BAEK ; Tai Young HUR
Korean Journal of Veterinary Research 2012;52(1):45-52
The present study was carried out to investigate the effect of barley and barley bran contaminated with Fusarium spp on growth performance and feed efficiency of fattening and growing pigs. In experiment 1, total 48 fattening Landrace pigs were used in a fattening trial for 71 days. Pigs weighing around 75 kg were allocated into different substitution groups containing 0, 10, 20 and 30% of barley contaminated Fusarium spp. In experiment 2, total 16 growing Landrace pigs were used in a growing trial for 45 days. Pigs weighing around 29.4 kg were allocated into different substitution groups containing 0, 5, 10 and 20% of barley bran contaminated Fusarium spp. Mycotoxin concentrations of barley and barley bran contaminated with 30% Fusarium spp were 0.452 and 1.049 ppm for deoxynivalenol, 8.125 and 17.646 ppm for nivalenol and 0.023 and 0.029 ppm for zearalenone, respectively. In experiment 1, no differences were found in weight gain and feed intake between control group (0%) and 10 or 20% substitution groups, but in 30% substitution group, weight gain and feed intake were significantly lower (p < 0.05) than those in control group. After slaughtering, the extended haemorrhage of the fundus region in stomach was observed in 20 or 30% substitution groups. In experiment 2, weight gain and feed intake were not significantly different among treatment groups. After slaughtering of experimental pigs, the extended haemorrhage of the fundus region in stomach was observed in pigs fed diet with 20% substitution group. These results suggest that the feeding of diet with contaminated highly levels of Fusarium spp was negative effect on growth and feed efficiency in growing and fattening pig.
Diet
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Fusarium
;
Hordeum
;
Stomach
;
Swine
;
Trichothecenes
;
Weight Gain
;
Zearalenone
4.A case of meningoencephalitis due to streptococcus pneumoniae in a patients with chronic graft-versus-host disease after allogeneic bone marrow transplantation.
Byung Wook KIM ; Jin Hong YOO ; Wang Shik SHIN ; Yang Lee KIM ; Moon Won KANG ; Dong Wook KIM ; Jong Wook LEE ; Jong Won PARK ; Choon Choo KIM ; Dong Jib KIM
Korean Journal of Infectious Diseases 1993;25(3):271-275
No abstract available.
Bone Marrow Transplantation*
;
Bone Marrow*
;
Graft vs Host Disease*
;
Humans
;
Meningoencephalitis*
;
Streptococcus pneumoniae*
;
Streptococcus*
5.A case of meningoencephalitis due to streptococcus pneumoniae in a patients with chronic graft-versus-host disease after allogeneic bone marrow transplantation.
Byung Wook KIM ; Jin Hong YOO ; Wang Shik SHIN ; Yang Lee KIM ; Moon Won KANG ; Dong Wook KIM ; Jong Wook LEE ; Jong Won PARK ; Choon Choo KIM ; Dong Jib KIM
Korean Journal of Infectious Diseases 1993;25(3):271-275
No abstract available.
Bone Marrow Transplantation*
;
Bone Marrow*
;
Graft vs Host Disease*
;
Humans
;
Meningoencephalitis*
;
Streptococcus pneumoniae*
;
Streptococcus*
6.Application of spherical coordinate system to facial asymmetry analysis in mandibular prognathism patients.
Suk Ja YOON ; Rui Feng WANG ; Hyeon Shik HWANG ; Byung Cheol KANG ; Jae Seo LEE ; Juan Martin PALOMO
Imaging Science in Dentistry 2011;41(3):95-100
PURPOSE: The purpose of this study was to compare asymmetric mandibular prognathism individuals with symmetric mandibular prognathism individuals using a new alternate spherical coordinate system. MATERIALS AND METHODS: This study consisted of 47 computed tomographic images of patients with mandibular prognathism. The patients were classified into symmetric and asymmetric groups. Mandibular and ramal lines were analyzed using an alternate spherical coordinate system. The length as well as midsagittal and coronal inclination angle of the lines was obtained. The bilateral differences of the spherical coordinates of the facial lines were statistically analyzed in the groups. RESULTS: There were significant differences between the groups in bilateral difference of the length and midsagittal inclination angle of the lines (p<0.05). The bilateral difference of the length and midsagittal inclination angle of the lines has significant correlation with chin deviation (p<0.05). CONCLUSION: The new alternate spherical coordinate system was able to effectively evaluate facial lines. The bilateral difference of lengths and midsagittal inclination of the facial lines might contribute to the facial asymmetry in mandibular prognathism individuals.
Chin
;
Evaluation Studies as Topic
;
Facial Asymmetry
;
Humans
;
Prognathism
;
Tomography, X-Ray Computed
7.Use of spherical coordinates to evaluate three-dimensional facial changes after orthognathic surgery.
Suk Ja YOON ; Rui Feng WANG ; Sun Youl RYU ; Hyeon Shik HWANG ; Byung Cheol KANG ; Jae Seo LEE ; Juan M PALOMO
Imaging Science in Dentistry 2014;44(1):15-20
PURPOSE: This study aimed to assess the three-dimensional (3D) facial changes after orthognathic surgery by evaluating the spherical coordinates of facial lines using 3D computed tomography (CT). MATERIALS AND METHODS: A 19-year-old girl was diagnosed with class III malocclusion and facial asymmetry. Orthognathic surgery was performed after orthodontic treatment. Facial CT scans were taken before and after orthognathic surgery. The patient had a menton deviation of 12.72 mm before surgery and 0.83 mm after surgery. The spherical coordinates of four bilateral facial lines (ramal height, ramal lateral, ramal posterior and mandibular body) were estimated from CT scans before and after surgery on the deviated and opposite side. RESULTS: The spherical coordinates of all facial lines changed after orthognathic surgery. Moreover, the bilateral differences of all facial lines changed after surgery, and no bilateral differences were zero. CONCLUSION: The spherical coordinate system was useful to compare differences between the presurgical and postsurgical changes to facial lines.
Facial Asymmetry
;
Female
;
Humans
;
Malocclusion
;
Orthognathic Surgery*
;
Tomography, X-Ray Computed
;
Young Adult
8.Docetaxel Monotherapy as Second-Line Treatment for Pretreated Advanced Non-Small Cell Lung Cancer Patients.
Yoon Ho KO ; Myung Ah LEE ; Yeong Seon HONG ; Kyung Shik LEE ; Hyun Jin PARK ; Ie Ryung YOO ; Yeon Sil KIM ; Young Kyoon KIM ; Keon Hyun JO ; Young Pil WANG ; Kyo Young LEE ; Jin Hyoung KANG
The Korean Journal of Internal Medicine 2007;22(3):178-185
BACKGROUND: Second-line chemotherapy offers advanced non-small cell lung cancer (NSCLC) patients a small, but significant increase in survival. Docetaxel is usually administered as a 3-week schedule, yet there is significant toxicity with this therapy. Therefore, a weekly schedule has been explored in several previous trials. In this retrospective study, we compared the efficacy and safety of a weekly schedule and a 3-week schedule of docetaxel monotherapy in a second-line setting. METHODS: Docetaxel was administered as 75 mg/m2 on day 1 every 3 weeks or as 37.5 mg/m2 on day 1 and 8 every 3 weeks until disease progression or severe toxicity developed. RESULTS: From October 2003 to March 2006, a total of 37 patients received docetaxel monotherapy and 36 patients could be evaluated. A total of 135 cycles were administered and then evaluated. The median overall survival was 13.3 months (95% confidence interval: 6.3~20.3) for the weekly schedule and 10.7 months (95% confidence interval: 8.3~13.0) for the 3-week schedule (p=0.41). The median time to progression was 3.0 months (95% confidence interval: 1.9~4.0) and 2.8 months (95% confidence interval: 1.0~4.6), respectively (p=0.41). The response rate was 16.7% for the weekly schedule and 21.1% for the 3-week schedule. The major form of hematologic toxicity was grade 3-4 neutropenia (3-week: 38.9%, weekly: 9.5%). The non-hematologic toxicities were similar between the two schedules. There were no treatment-related deaths. CONCLUSIONS: A docetaxel weekly schedule was very tolerable and it had comparable activity to that of the 3-week docetaxel schedule. Considering the efficacy and tolerability, a docetaxel weekly schedule can be an alternative schedule for the standard treatment of NSCLC in a second-line setting.
Adult
;
Aged
;
Antineoplastic Agents/*administration & dosage/adverse effects
;
Carcinoma, Non-Small-Cell Lung/*drug therapy/pathology
;
Drug Administration Schedule
;
Female
;
Humans
;
Lung Neoplasms/*drug therapy/pathology
;
Male
;
Middle Aged
;
Neoplasm Staging
;
Retrospective Studies
;
Taxoids/*administration & dosage/adverse effects
;
Treatment Outcome