Occupational Health

It is one heated topic to enhance the humanistic quality of current college students.This paper investigates and analyzes the status quo of humanistic education among the college students in two medical colleges in Tianjin city,exploring related issues in the humanistic education in the English language lecture teaching in medical colleges.

Asthma is heterogeneous disorder which caused by a complicated interaction between multiple genes and environmental factors. A increasing number of attention has paid in the researches about its pathogenic mechanism and therapeutic strategies. Not only can Toll-like receptors and signal transduction pathways mediate relevant immunocyte of asthma, but also induce or restrain development of asthma. TLRs is a land of pattern recognition receptor(PRRs), which can rely on the conserved sequence of gene encoding to identify pathogenic microorganism, meanwhile activate innate immunity,adjust acquired immunity and induce immune tolerance.

Objective To evaluate the effectiveness of transitional care model on life quality of patients with Alzheimer's disease in China.Methods The literatures of randomized controlled trials (RCT) of transitional care of patients with Alzheimer's disease in mainland China published in Chinese or English were enrolled in this review.RevMan5.1 software was used to analyze the data.Results Twelve articles met the inclusion criteria.The scores of mini-mental state examination (MMSE),health state survey questionnaire (SF-36) of the intervention group was higher than the control group,which had a significant difference.While no significant difference was found in the scores of activities of daily living (ADL) between the intervention group and the control group.Conclusions Transitional care can improve cognitive function and quality of life of patients with Alzheimer's disease in China.

Objective:The short term results of laparoscopic radical hysterectomy and pelvic lymph nodes dissection for early uterine malignancy were investigated.Methods:70 patients with eady malignant uterine tumor who underwent a laparoscopic radical hysterectomy and pelvic lymph nodes dissection(TLRH+LPL)were retrospectively reviewed.At the samt time,48 patients were recruited to be the control group who had laparotomy radical hysterectomy and pelvic lymph nodes dissection(ARH+APL).Intraoperative and postoperative situations and complications between these two groups were analyzed.Results:70 patients underwent laparoscopic operation,but two cases changed to laparotomy(transfer rate 2.9%).The mean operation time,blood loss,number of dissected pelvic lymph nodes and postoperative temperature recovery time of TLRH+LPL group was significantly different from ARH+APL group(P<0.01),while there were no difference between these two groups on bladder function recovery time and occurance of postoperative complications.Conclusions:TLRH+LPL has the same feasibility and safety with ARH+APL,less invasive to the tissue,thus offers a good option of microinvasive therapy for female malignant tumor.

OBJECTIVE: To introduce the sorts of biomedical fibers, collagenous fibers, chitin fibers polyactic acid(PLA) fibers, etc. , and their preparation,properties and application respectively, and suggest China to pay attention to the research and development of biomedical fiber.DATA SOURCES: Literatures from January 1993 to December 2001 were computer-searched in http://www.sciencedirect.com, http://worldscinet.lib.tsinghua.edu.cn, with the key words of "biomedical and polymer,fibre" and the language was limited to English.: Literatures from January 1999 to December 2004 were computer-searched in http://www.wanfangdata.com.cn,with the key words of "Biological, medical, polymer and Chitin Fibers" and the language was limited to Chinese.STUDY SELECTION: Inclusion criteria: ①Chitin fibers②Collagenous fibers and PLA fibers③Alginic acid fibers④Polyglycolide fibers⑤β-hy droxybutanoic acid ester (PHB)⑥Polycaprolactone fiber. Exclusion criteria:① Obsolete literatures. ② Repeated study. DATA EXTRACTION: Totally 60 tests on biomedical fiber were collected, but only 15 literatures met the inclusion criteria. Altogether 45 literatures were excluded due to older and repeated study.DATA SYNTHESIS: ①The sorts of biomedical fibers: Classified according to the sources, biomedical fibers include metal ones (e.g. stainless steel wire), inorganic and nonmetal ones (e.g. alumina fibers) and macromolecular ones. Classified according to the interaction between living tissues and materials, they include bioinert fibers, bioactive fibers and bioabsobable fibers. Classified according to biomedical use, they include biomedical fibers compatible with hard tissues, biomedical fibers compatible with parenchyma, biomedical fibers compatible with blood and biomedical fibers used as medicine or for regulating the release of medicine ②The main biodegradable fibers include chitin fibers, collagenous fibers, PLA fibers and their copolymer fibers.CONCLUSION: As one of the important functional fibers, the biomedical fibers attract wide attention both at home and abroad. The research and development about them are still on the way and has shown hopeful prospective of application. Much attention should be paid on the research and development of biomechanical fibres.

Objective　To study the malignant or benign characters of lung mini nodules for diagnosis and treatment.Methods　A retrospective analysis was performed on 80 post-operative cases with pathologically confirmed malignant or benign lung mini-nodules.Results　Lung mini-nodule resection cases accounted for 17.7%(80) out of a 451-cases group.Malignant cases accounted for 73.7%(59/80)，benign cases 26.3%(21/80).Most of the malignant cases were squamous cell carcinoma and adenocarcinoma,while most of the benign cases were tuberculosis and inflammatory pseudo-neoplasms.As for pTNM staging in malignant cases,there were 28 in pT1N0M0，19 in pT1N1M0,1 in pT1N1M1,10in pT1N2M0 and 1 in pT1N2M1;the average survival time was 29.4 months.The accurate rate of pre-operative X-ray and CT scan was 45% and 76.2% respectively.Conclusion　For patients with lung mini-nodules ＜2 cm CT value at 37HU,and the nature unknown ,resection is suggested.

PurposeTo explore the CT features and its diagnostic value of mediastinal congenital bronchogenic cysts.Materials and MethodsThe clinical findings and CT manifestations of 14 patients with mediastinal bronchogenic cysts confirmed by surgery and pathology were retrospectively analyzed, among which 12 were performed by both plain and enhanced CT scan, and the other 2 only received either plain or enhanced CT scan.ResultsAll the patients presentedfluid-filled cysts, and 3 of them had CT number lower than 20 HU, 7 cases from 20 to 60 HU, and 4 more than 60 HU. Four patients had lesions in anterior mediastinum, 4 others in posterior mediastinum, and all the 8 lesions were on the left side; 6 patients had lesions in middle mediastinum, among which 5 lesions were on the right side; and 1 case of posterior bronchogenic cysts cancerated into adenocarcinoma.ConclusionMediastinal bronchogenic cysts can appear in any part of mediastinum; lesions in middle mediastinum are more likely to occur on the right side, whilst lesions in anterior and posterior mediastinum are often located on the left side. The typical CT manifestations show well-defined round or oval masses of homogeneous soft-tissue or cysts with watery density.

Objective To explore the relationship between physical activity ( PA) in college students and self?efficacy,and provide guarantee for improving health education in colleges. Methods International physical ac?tivity questionnaire( IPAQ) ,scales of physical behavior,scales of stage of change in physical exercise behavior,and scales of self?efficacy were used to test 504 students from some of colleges in Zhejiang province. Results Signifi?cantly more males (38.52%) than females (27.27%) were in the high activity tertile (P<0.01); the amount of PA per week in males and females were (4608±872.07)MET and(4361±674.03)MET(P<0.01); the scores of males and females were (3.32±0.44) and(3.04±0.36),(P<0.01). The number of males (35.5%) in maintenance period and period of action is greater than that of females (28.9%). Males had higher self?efficacy and more scores of behavior than females (P<0.05) . There were significant characteristics of PA in their self?efficacy,score of be?havior and stages of change( F=18.38, F=15.08, F=34.71, P<0.01),and a significant correlation between PA and self?efficacy,stages of change and physical exercise behavior ( r=0.336, r=0.36, r=0.46, P<0.01).Conclu?sion Self?efficacy may have important effect on the level of PA. Stages of change and scores of behavior may ex?plain difference of PA between males and females.

Objective:To establish an HPLC method compatible with the mass spectrometry for the determination of the content and related substances in amlodipine besylate tablets. Methods:The sample was separated on a CAPCELL PAK C18 column (250 mm × 4. 6 mm, 5 μm) with the mobile phase consisting of methanol and 20 mmol·L-1 ammonium acetate (60∶40) at a flow rate of 1. 0 ml·min-1 . The detection wavelength was set at 237 nm. The column temperature was 35℃ and the injection volume was 20 μl. Be-sides, an HPLC-QTOF MS method was used to identify the molecular structure of the related substances of amlodipine. Results: The related substances were completely separated from amlodipine. The linear range of amlodipine besylate was 10-100 μg · ml-1 ( r =0. 999 8), and the mean recovery was 99. 2%(RSD=1. 0%,n=9). The main related substances could be detected by HPLC-QTOF MS. Conclusion:The established method is accurate, reliable and reproducible, which can be used in the quality control of amlodip-ine besylate tablets.