Asthma is heterogeneous disorder which caused by a complicated interaction between multiple genes and environmental factors. A increasing number of attention has paid in the researches about its pathogenic mechanism and therapeutic strategies. Not only can Toll-like receptors and signal transduction pathways mediate relevant immunocyte of asthma, but also induce or restrain development of asthma. TLRs is a land of pattern recognition receptor(PRRs), which can rely on the conserved sequence of gene encoding to identify pathogenic microorganism, meanwhile activate innate immunity,adjust acquired immunity and induce immune tolerance.

It is one heated topic to enhance the humanistic quality of current college students.This paper investigates and analyzes the status quo of humanistic education among the college students in two medical colleges in Tianjin city,exploring related issues in the humanistic education in the English language lecture teaching in medical colleges.

Occupational Health

Breast Neoplasms ; diagnosis ; therapy ; Combined Modality Therapy ; Female ; Humans ; Mammography

E. coli mutant has been used as an assay organism for vitamin B12activity by many workers. The difficulty encountered in this method is theinterfering-action of metmonine. Fermented soybean products contain large.amount of this amino acid, thus the usual alkaline treatment method could not be used for the determination of vitamin B12 activity in these.products. A method for the separation of vitamin B12 from methionine has been developed by the authors. The sample extracted is prepared by the usual method and the extract passed through an active carbon absorption column, Then washing the column with pH 4.5 sodium acetate buffer solution removes methionine and finally vitamin B12 is eluted off with hot 65% alcohol Alcohol in the eluate is removed under reduced pressure and the methionine in the residue is in trace amount which can be corrected by the alkaline treatment. The recovery of vitamin B12 from the adsorption treatment ranges,from 95% to 101.3%, with an average of 98.8%.Nine kinds of Chinese -fermented soybean products have been assayed by this method. Fermented soybean curd with strong smell is a good dietary source of vitamin B12 activity, and it contains 1.88-9.80 r per 100 grams.

Background and purpose:Chemotherapy is the main treatment for advanced non-small cell lung cancer (NSCLC).This treatment can alleviate symptoms,improve the quality of life and elevate the survival rate.Due to serious adverse reaction however,it is very difficult for patients to complete chemotherapy.Elemene emulsion has extensive antitumor effects,mild adverse reaction and the therapeutic effect.The purpose of this study was to explore the efficacy of combining NP (NVB+DDP) chemotherapy with elemene emulsion in a comprehensive treatment of advanced NSCLC.Methods:60 cases of patients with advanced NSCLC were randomly divided into the treatment group and the control group,each group consisted of 30 cases.The treatment group was treated with a combination of NP (NVB+DDP) chemotherapy with elemene emulsion (400 mg d2-d8),while the control group was treated with only the NP chemotherapy.Results:The efficacy in the treatment group was 56.7% and 40% in the control group.There was a significant difference between the two groups in terms of their treatment response (P

The change of the ascorbic acid content in several vegetables at the different steps in the cooking process was studied. Special attention was directed to washing before or after cutting the vegetable into pieces of different size.Large-scale and household cooking methods were compared. The effect of storing the cooked vegetable at different temperatures and for different lengths of . time was also investigated.The loss of the total and reduced ascorbic acid in spinach, colza, cabbage and celery cabbage was insignificant after washing either before or after cutting. The loss was also not appreciable when these vegetables were held for 2 and 6 hrs. after cutting into wedges. When potatoes and cabbage were cut into strips, there was no change in the total ascorbic acid but a slight decrease of the reduced form. A marked loss of total ascorbic acid was observed when potatoes strips and slices were soaked in water; the slices lost 11.2% and 12,.8% and the strips lost 22.6,% and 23.9% respectively by the end of 2 and 6 hrs. When potatoes were cut and kept in the air at room temperature for 2 and 6 hrs., there was no change in total ascorbic acid, but an increase of the reduced form was apparent. Such an increase should not be attributed to the so-called "traumatic formation"; some changes in the redox system of ascorbic acid is to be expected.A certain amount of ascorbic acid was lost when'spinach, garlic green, colza and celery cabbage were cooked either in large or in small quantities. The retention of the reduced ascorbic acid in the vegetables cooked in small quantit ies ranged 50.2-64.1.%, and that of the total ranged 72.6-75.7%. In case of the large-scale cooking, the retention of reduced and total ascorbic acid ranged 53.6-70.5% and 73.9 - 85.4% respectively. No loss of ascorbic acid was observed when the potatoes were steamed whole, but a large amount was lost when their strips were scrambled in a Chinese style.Cooked vegetables held at 60℃ for 2 and 4 hrs. lost a part of its ascorbic acid; the percentage of loss in the 2 hr. period was lower than that in the 4 hr.

Seawater,hyperosmotic and alkaline, is a complex wound factor. Specific pathophysiological changes appear when wounds are socked in seawater. and special treatments are needed for such injuries. This paper reviewed the pathophysiological changes and treatment of seawater-soaked soft tissue wound, cranioccrebral trauma, open chest trauma,open ahdom-inal trauma,sea water drowning and seawater immersion during shock.

0.05)。But the DNA,RNA content and lactase activities and maltase activity in the small intestine mucosa in I-fed piglets were significantly greater than those of P-fed piglets. Conclusions:These results show that insulin influences the enzymatic activity and the proliferation of intestinal epithelial cells of IUGR newborn piglets.

Objective To detect the expression of oh8dG in gastric tissues and discuss the carcinogenicity of Hp.Methods oh8dG was detected with immunohistochemistry in Hp positive and Hp negative tissues.Results In immunohistochemistry,the positive rates of oh8dG expression in Hp positive and Hp negative tissues were 78% and 8%,respectively(P