2.The determination of immune functions of mouse experimental pyelonephritis infected with c. albicans
Li WANG ; Shu WANG ; Shao-Lun ZHANG ;
Chinese Journal of Immunology 1985;0(02):-
A pyelonephritis model of mouse is made by c. albicans infection. The determination of im-mune functions in model show that, both proliferation response of T cell to ConA and IL-2 activ-iting of spleenocytes of model animal to inductionwith ConA increased at 30 days after injected.The proliferation response of B cell to stimulation with LPS inhanced from 15 through 30 days,primary Ab response of model animal to SRBC stimulation inhanced between 15-30 days afterimmunization. DTH response to stimulation with c. albicans protein Ag raised since 15 days andup to peak at 30 days. Agglutination titer of serum raised up 15 days, and remained at higherlevel untill 30 days.
3.Clinical observation of modified hydroxyapatite implant in scleral shell
International Eye Science 2014;(10):1904-1905
AIM: To evaluate the clinical effects of modified hydroxyapatite implant in scleral shell.
METHODS: Thirty - four cases were performed eye evisceration, autogenous sclera shell anterior and posterior petaloid shape with posterior sclera fenestration, hydroxyapatite artificial eyeballs were implanted at stage I, and conjunctival wound, orbital activity and other complications were observed after surgery.
RESULTS:The follow-up was 6 ~12mo. There was no patients with implant exposure, sclera dissolution, conjunctival wound dehiscence, conjunctival sac constriction noted. All the patients got good activity of artificial globe, and the active range of side motion of the HA was 10o ~15o. The artificial eyes looked symmetrical, and the eyes socket were full.
CONCLUSION: The modified hydroxyapatite implant in scleral shell can maintain the normal anatomy of the orbital tissue, and also can get full eyes socket and good activity, It was an easy and simple surgery which could obtain satisfactory clinical effect and less complications.
4.Comparative study of the therapeutic effect of functional electrical stimulation and ankle-foot orthosis in improving walking function in stroke patients
Yixi LUN ; Qiang WANG ; Yongxiang ZHANG
Chinese Journal of Physical Medicine and Rehabilitation 2014;36(5):357-360
Objective To compare the clinical therapeutic effect of functional electrical stimulation (FES) and ankle-foot orthosis (AFO) in improving walking function in stroke patients.Methods Thirty-six stroke patients satisfying the enrolling criterion of the research were randomly divided into two groups:FES group and AFO group (n =18 in each).Both groups received the same routine rehabilitation therapy and medical treatment.Patients of FES group received FES of common peroneal nerve and tibialis anterior muscle of the affected limb,30 min per day,5 days per week,4 weeks in total,while the patients of AFO group received walking training with AFO wearing on,30 min per day,5 days per week,4 weeks in total.Walking function was assessed by 10-meter maximum walking speed,timed-up and go test (TUGT),functional ambulation category(FAC),the muscle tension of ankle flexor and Brunnstrom stage,which were carried out before treatment and four weeks after treatment.Results Before treatment,there was no significant difference between the two groups for the baseline of measurement(P > 0.05).After 4 weeks of treatment,10MWT,TUGT,FAC scores and Brunnstrom stages in the two groups significantly increased (P < 0.05).The 10MWT,FAC scores and Brunnstrom stage increased more significantly in FES group than those in AFO group (P < 0.05).There was no significant differences with regard to TUGT and the muscle tension of ankle flexor between the two groups (P > 0.05).Conclusions Both FES and AFO can accelerate the recovery of walking function in hemiplegia patients.FES can improve the walking ability in patients with stroke more significantly.
6.Observation of early active training effects after the operation for lumber intervertebral disc herniation
Qing CHEN ; Jichang GAO ; Lun WANG ;
Chinese Journal of Tissue Engineering Research 2002;6(2):286-287
Objective To explore the recent and distant effects of early active training after the operation for lumber intervertebral disc herniation.Method 79 patients after the operation for mono segmental lumber intervertebral disc herniation had been divided into early active training group and routine control group randomly, and accepted training, regular re examination, and follow up of 1~ 6 years respedtively.Results The early active training group had better recent and distant objective effect, and more patients (97.6% ) were satisfied with the operational effects.Conclusions The early active training after the operation for lumber intervertebral disc herniation is positive significant for operational effects.
7.Effect of CT-aided Scalp Surrounding Needling on Infarction Dementia by Retaining Long Time
Lei LIU ; Xin LUN ; Yifeng WANG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(6):569-571
Objective To observe the effect of CT-aided scalp surrounding needling on infraction dementia by retaining long time. Methods 53 infraction patients following dementia were randomly divided into treatment group (n=26) and control group (n=27). The control group was treated with CT-aided scalp surrounding needling for 30 minutes, while the treatment group was treated with CT-aided scalp surrounding needling for 3 hours. The course was 8 weeks. The therapeutic effect was assessed by Mini-Mental State Examination(MMSE), Hasegawa Dementia Scale(HDS-R) and Activities of Daily Living (ADL). Results The scores of ADL, MMSE, and HDS-R improved obviously after treatment in two groups (P<0.05), and the treatment group was better than the control group (P<0.05). Conclusion CT-aided scalp surrounding needling by retaining long time may facilitate to enhance the clinical effect on infarction dementia.
8.C_(2,3) pedicle screw fixation through cervical posterior approach in treatment of Hangman's fracture
Lun WAN ; Bin ZHANG ; Zhongqian LIU ; Yue WANG
Chinese Journal of Tissue Engineering Research 2007;0(09):-
AIM: To evaluate the clinical outcomes and evaluate the application value of pedicle screw system internal fixation in short segment for the treatment of Hangman's fracture. METHODS: A retrospectively analysis was conducted in 17 cases of Hangman's fracture who were treated in Department of Orthopaedics, Sichuan Provincial People's Hospital since 2004. According to Levine-Edwards classification, 4 of them belonged to type II, 6 type IIA, 7 type III. According to Frankel classification in function of spinal cord, 12 cases of them belonged to Grade E and 5 cases D. All cases were fixed with C2,3 pedicle screw system short segment implantation materials (product of Medtronic Sofamor) after skull traction and reduction. RESULTS: No vertebra artery injury or spinal injury was found during operation. Postoperational photograph and CT detection revealed bilateral fracture had no reduction in 1 case and cerebrospinal fluid leaking occurred in 1 case who was cured after conventional therapy. All cases were followed up for 12-24 months (average 14.5 moths). All fractures healed within 6 months, and activities of cervical vertebra were not obviously limited. As for nerve function, 4 cases of Grade D recovered up to Grade E. Ti-alloy implant materials used in this study were well biocompatible to the human body. There were no blood, immune, histology reactions, or the corrosion and abrasion of Ti-alloy appeared. CONCLUSION: Pedicle screw fixation in short segment for the treatment of Hangman's fracture is satisfactory in fracture reduction, fixation and healing. There are little lose in function of cervical vertebrae and it promotes functional recovery of spinal cord.
9.Effects of passive smoking on vascular endothelial function in office women
Liang YU ; Mei WANG ; Li GAO ; Wendong QU ; Lun LIU
Chinese Journal of General Practitioners 2008;7(7):453-455
Objective To explore the effects of passive smoking on vascular endothelial function in office women.Methods Totally,94 healthy office women volunteers from urban(36 women)and townships or towns(58 women)were divided into three groups based on the extent of their daily exposure to passive smoking,group A exposed to one to eight cigarettes,group B exposed to nine to 15 cigarettes,and group C exposed to more than 15 cigarettes,respectively,with 20 healthy young women without exposure to passive smoking as controls.Internal diameter of the brachial artery Was measured by color Doppler ultrasound scanning for each of the participants and its changes were observed before and after congestive reaction of the brachial artery test and nitroglycerin test.Results Thirteen of 36 office women from urban and 38 of 58 from townships or towns exposed to passive smoking of more than eight cigarettes daily,with chi-square of 7.74,P=0.0054.The brachial artery in groups A,B and C dilated less than that in the controls did.The brachial artery in group C dilated less than that in the groups A and B did.Conclusion Passive smoking could damage vascular endothelial dilatation function in office women.
10.Analysis of a survey result of Keshan disease in Zhangjiakou City of Hebei Province in 2010
Pei-lun, HUA ; Zhong-xiang, WANG ; Jie, TAN
Chinese Journal of Endemiology 2013;32(4):436-438
Objective To study Keshan disease and its developmental trend in Zhangjiakou City in 2010 and to provide a scientific basis for further prevention of the disease.Methods From the eight diseased counties of Zhangjiakou City,five diseased countries were selected; in each diseased county a diseased village was selected as the clinical investigating point.Physical examination and Electrocardiography (ECG) tracings were carried out to suspicious patients with Keshan disease.Suspected heart enlargement,and ECG abnormalities were taken anteroposterior chest X-ray to measure the cardiothoracic ratio.Results A total of 2519 people were examined,16 cases were diagnosed as chronic Keshan disease,79 as latent Keshan disease,and the detection rate was 0.64% (16/2519) and 3.14%(79/2519),respectively.Total of 2519 ECG tracings were taken,and electrocardiogram abnormalities were 268 cases,with a abnormal rate 10.64%,and most of them were complete right bundle branch block[accounted for 17.16% (46/268)].Totally 94 cases of anteroposterior chest X-ray films were taken and 42 cases were cardiac enlargement,with a detection rate 44.68%.The numbers of mild,moderate and severe cases were 20,12 and 10,respectively,and the constituent ratio was 47.62% (20/42),28.57% (12/42),23.81% (10/42),respectively.Conclusions The incidence of Keshan disease in Zhangjiakou City is relatively low,and the condition is stable.But monitoring and comprehensive prevention and control measure still should be strengthened.