Objective To investigate the clinical efficacy of acupoint application in treating senile hypertension of yin deficiency and yang excess type.Methods Sixty-six old patients with hypertension of yin deficiency and yang excess type were randomly allocated to treatment and control groups, 33 cases each. The control group took nifedipine controlled release tablets and the treatment group received acupoint application in addition. The quality of life score was recorded in the two groups before and after treatment. The clinical therapeutic effects were compared between the two groups.Results The total efficacy rate in reducing blood pressure was 90.0% in the treatment group and 84.8% in the control group; there was no statistically significant difference between the two groups (P>0.05). The total efficacy rate in improving the symptoms was 90.9% in the treatment group and 69.7% in the control group; there was a statistically significant difference between the two groups (P<0.05). There was a statistically significant pre-/post-treatment difference in the quality of life score in the two groups (P<0.05). There was a statistically significant post-treatment difference in the quality of life score between the treatment and control groups (P<0.05).Conclusions Acupoint application is an effective way to treat senile hypertension of yin deficiency and yang excess type. It can improve the quality of life in the patients.

VB programme and flash technique are used to visually display physical mechanism of blood cell velocity measurement in vein taken by Doppler ultrasonic blood equipment.

Objective　To investigate the changes and its clinical significance of plasma neuropeptide Y(NPY) concentration in patients with pregnancy induced hypertension (PIH). Methods　Plasma NPY levels were detected by radioimmunoassay in 30 patients with PIH, 20 normal non-pregnant women and 23 normal pregnant women. The PIH group was subdivided into mild, moderate and Severe subgroups, and the NPY concentration was also measured in these subgroups respectively at admission and one week after delivery. Results　The plasma NPY levels in patients with PIH ［(164.16±68.32) ng/L］ were significantly higher than those of normal non-pregnant women and normal pregnancies ［(86.60±20.65) ng/L, (82.42±12.46) ng/L, P<0.01, respectively］. There was significant difference among plasma NPY levels among the patients with mild, moderate, and severe PIH at admission (P<0,01). At one week after delivery the concentrations of plasma NPY were significantly decreased in the moderate and severe subgroups compared with the value measured at admission (P<0.01). Moreover, the NPY levels in patients with severe PIH after delivery were still higher than those of normal non-pregnant women. Conclusions　The results suggested that the level of NPY in plasma is increased in women with PIH. Elevated plasma NPY levels may play a key role in the development of PIH.

Objective To discuss the inflexion question in the course of measuring surface tension coefficient.Methods Metal frames with different lengths,radials and metal cylinders with different inside & outside radials were used to measure the inflexion.Results The inflexion appeared in the course of measuring surface tension coefficient by using force sensor and the inflexion changed with the different radials and lengths of the metal frames.Conclusion The thickness and bending of the fluid membrane results in the change of inflexion,and the inflexion can be avoided with the length and radial chosen properly.

Objective To explore the surgical anesthesia in patients with schizophrenia, clinical effect of two drug combination.Methods40 cases of anesthesia for the patients with schizophrenia surgery using fentanyl combined with propofol, and classified as the control group, the other 40 patients used remifentanil combined with propofol anesthesia and the patients were classified as observation group.In our hospital from October 2016 to March 2015.ResultsComparing the two groups of patients with heart rate and blood pressure, found in the two groups had no significant difference before anesthesia after anesthesia, intervention at different time points showed corresponding differences (P<0.05) shows significant differences.Compared two groups of patients, the recovery time of the surgery, the patients in the observation group were relatively fast, comparison between groups (P<0.05) showed obvious differences.The adverse reactions in two groups were 0%, comparison between groups have no significant difference.ConclusionTwo drug combination has better effect in schizophrenia patients in surgical anesthesia, compared with fentanyl and remifentanil for anesthesia, the latter effect is better, at the same time combined treatment for patients with heart rate had little effect, conducive to the patient recovery after surgery, and no adverse reaction for patients, the drug safety, it is worthy of reference.

In the present paper,the authors make a summary about the development of acupuncture needles in Chinese ancient times recorded in the literature,and have a discussion on the effect of the thickness of acupuncture needles on clinical the-rapeutic efficacy in accordance with modern medical theories,the development of its clinical application and by combining their own experience in acupuncture practice. They conclude that the thickness of the abdominal needle is a negligible factor influencing the therapeutic efficacy of the reinforcing-reducing manipulations. In the treatment of deficiency pattern disorders,a thinner acupuncture needle is suitable,while for excess syndrome,a thicker acupuncture needle is recommended. In the light of the patient's constitution and different state of clinical conditions,a flexible application of the acupuncture needle with different diameters is highly recommended in clinical practice. In this way,the clinical therapeutic effect would be improved much.

There are 5 literatures related to the clinical applications of cancer vaccination in hematologieal malignancies in the 18th annual meeting of the European Hematology Association (EHA).This article provides an overview of these literatures that helps to understand how cancer vaccination can be explored for future clinical interventions.

Aim To study the role of nitric oxide by measuring the expression and activity of nitric oxide synthase in hippocampus of rats tolerance and dependence to the anticonvulsant action of flurazepam.Method Animal models of toleran and dependence to flurazepam were established. Nitric oxide synthase in hippocampus was measured using Western blot and immunohistochemistry, and its activity was evaluated using colorimetry. Result Hippocampal nNOS increased in rats tolerance to flurazepam. In rats dependence to flurazepam, hippocampal nNOS increased but without statistical significance. Total NOS activity increased dramatically both in flurazepam tolerane and dependene rats.Conclusion NO may play a role in rats tolerance and dependence to the anticonvulsant action of flurazepam.

OBJECTIVE:To probe into the situation of drug use that goes beyond the scope of package inserts in pediatrics of our hospital and to promote clinical rational drug use.METHODS:A total of 3 142 prescriptions between Mar.and Apr.2006 collected from the pediatric out-patient department of our hospital were analyzed in accordance with the contents of the related drug package inserts.RESULTS:Of the total 3 142 prescriptions,345(11.0%) involved drug use that goes beyond the scope of package inserts,leading the list were prescriptions of infants,accounting for 71.3% of the total.The problems such as age(52.2%) and indication(36.5%) were the main type;respiration system drugs(48.4%) and the antibiotics(40.6%) were the main drug kinds involved.CONCLUSIONS:It's widespread for drug use that goes beyond the package inserts in the pe-diatrics,which conforms to evidence-based medicine and the spirit of philosophy and ethics,but against the principle of law,which thus should be given fully attention in the clinic.

In recent years, the incidence of the allergic skin diseases is increasing as the growing of the pressure, the changes of the environment and other factors. The clinical features of the allergic skin diseases are easily repeated and in long course. It is found that the incidence of clinical allergic skin diseases, in addition to the season, diet and emotional relevant, is also closely linked to the physical deterioration of patients. Therefore, in addition to the emphasis on the treatment of the current symptoms of patients, adjustment and treatment of phsical constitution of patients and improvement of the adaptability of patients to environmental changes should attract attention, thereby reducing the frequency of incidence and alleviating the symptoms. The application of the abdominal acupuncture combined with body acupuncture for the improvement of the symptoms and physical constitution of allergic skin disease patients has obvious efficacy, which should be applied and promoted in clinic.