1.A study on the mRNA expression of the glucose transporter gene in the diabetic rats
Chinese Journal of Diabetes 1993;0(00):-
The study was proceeded on the mRNA expression of the GULT1 and GLUT4 gene in the alloxan diabetic rats by the technique of dot-blot hybridization analysis. The results showed that the levels of the GLUT4 mRNA expression were reduced in diabetic rats while increased in insulin treated diabetic rats. This suggests that the reduced GLUT4 mRNA expression which could affect the quantity of its posttranslational products may be one of the causes of the insulin resistance.
2.Medical service in high & cold mountainous region in future war
Chinese Medical Equipment Journal 2004;0(09):-
Based on experience on medical service drilling for many years,this paper analyses the hardship and complexity of medical service support in high & cold mountainous region.It also puts forward some suggestions in such aspects as integral design,focal points insurance,necessaries reinforcement,preach for popularization and mutual cure training.
4.Diagnosis and emergency treatment of intracranial hypotension syndrome in children
Chinese Pediatric Emergency Medicine 2011;18(5):400-402
Intracranial hypotension syndrome is easily underestimated by doctors and patients,but its occurrence is not infrequent.Primary intracranial hypotension is usually associated with cerebral blood vessel disturbance and infections.Secondary intracranial hypotension is usually secondary to iatrogenic and other diseases or trauma.The main manifestation of intracranial hypotension syndrome is postural headache which may be diagnosed by cerebrospinal fluid pressure measurement during lumber puncture.The headache can disappear by posture adjustment in most children,or by water intake or intravenous administration of hypotonic (0.5%)or saline in serious case.Prognosis is good and precaution is most important for all.
5.Research involved with 5-Fu metabolize and resistance mechanism
Cancer Research and Clinic 2009;21(1):67-69
5-fluorouracil (5-Fu) as an antimetabolite drug,has been widely used in the treatment of various solid tumors.However, due to the heterogeneity of tumor and the impact of the individual, some patients still have drug resistance or serious lethal toxicity reaction.The text focuses on the research progress of pharmacogenomics and pharmacogenetics of some forecast elements which affect the efficacy and toxicity of 5-Fu,and discussed their guiding role on the choice of chemotherapy drugs.
6.CT Manifestations of Mediastinal Congenital Bronchogenic Cysts
Chinese Journal of Medical Imaging 2014;(11):820-823
PurposeTo explore the CT features and its diagnostic value of mediastinal congenital bronchogenic cysts.Materials and MethodsThe clinical findings and CT manifestations of 14 patients with mediastinal bronchogenic cysts confirmed by surgery and pathology were retrospectively analyzed, among which 12 were performed by both plain and enhanced CT scan, and the other 2 only received either plain or enhanced CT scan.ResultsAll the patients presentedfluid-filled cysts, and 3 of them had CT number lower than 20 HU, 7 cases from 20 to 60 HU, and 4 more than 60 HU. Four patients had lesions in anterior mediastinum, 4 others in posterior mediastinum, and all the 8 lesions were on the left side; 6 patients had lesions in middle mediastinum, among which 5 lesions were on the right side; and 1 case of posterior bronchogenic cysts cancerated into adenocarcinoma.ConclusionMediastinal bronchogenic cysts can appear in any part of mediastinum; lesions in middle mediastinum are more likely to occur on the right side, whilst lesions in anterior and posterior mediastinum are often located on the left side. The typical CT manifestations show well-defined round or oval masses of homogeneous soft-tissue or cysts with watery density.
7.Application of nicardipine induced hypotension in endoscopic sinus surgery
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(05):-
OBJECTIVE To investigate the advantages of nicardipine induced hypotension in endoscopic sinus surgery.METHODS Eighty patients underwent endoscopic sinus surgery under general anesthesia were randomly assigned into two groups(n=40 each):Group A(Enflurane Group), Group B (Nicardipine Group).The effect of controlled hypotension was compared between the two groups.The changes of MAP, HR were recorded during induced hypotension, the time of induction, maintenance and recovery in induced hypotension were recorded.RESULTS 1.The induced hypotension induction time in group A was significant shorter than that in group B, BP recovery time in group A was obviously longer than that in group B (P
8.New mission of medical science education: Promotion of translational medicine
Chinese Journal of Medical Science Research Management 2010;23(4):225-228,264
In recent years, basic medical researches and their cost have been developing rapidly,however, the development of clinical researches is very slow. In fact, only a few basic researches can be translated to clinical application, and the promoting role of basic research for clinical practice is very limited. This produces a wide gap between basic research and clinical research, which seriously hindered the progress of medical science and the advancement of public health. Translational medicine came into being under this condition, and is now being understood and utilized by scholars worldwide. This paper summarizes some features and new advances of translational medicine. Meanwhile, the authors put forward suggestions to strength translational medicine in China according to the status quo of health care reform and the medical research and education in Chinese hospitals, which could help to relieve the dissatisfaction among the government, the society and the public toward the mismatch of basic medical research and clinical research, and to promote harmonious development of medical science.
9.Research progress of lung injury following cardiopulmonary bypass
Journal of Medical Postgraduates 2003;0(09):-
Postoperative pulmonary dysfunction in patients undergoing cardiopulmonary bypass(CPB) is a significant clinical problem and has long been recognized by cardiac surgeons. The studies of the pathogenesis and protection strategies of CPB induced lung injury have been the focus in the field of cardiac surgery. This review presents the recent progress of the pathogenesis and protection strategies of lung injury following CPB.
10.The diagnosis and predictor of the acute lung injury following cardiopulmonary bypass
Journal of Medical Postgraduates 2003;0(05):-
Acute lung injury (ALI) is one of the most important complications after cardiopulmonary bypass (CPB) and the complex pathophysiology remains to be resolved incomplete. At present, there is no specific and uniform criterion about the diagnosis of ALI following CPB. The changes of physiology and biochemistry in the lung can indicate the development of the ALI, and give proof of the early diagnosis of ALI following CPB.