1.Clinical efficacy of Longxuejie joint cobamamide in the treatment of elderly patients with herpes zoster
Chinese Journal of Primary Medicine and Pharmacy 2014;(19):2963-2964
Objective To investigate the clinical efficacy of cobamamide combined with Longxuejie in the treatment of herpes zoster in the elderly .Methods 104 elderly patients with herpes zoster were randomly divided into the treatment group and the control group .Both the two groups were given orally famciclovir 250mg,3 times a day for 14 days,intramuscularly injected gland glycosides cobalamin 500mg,1 day,14 days a course of treatment ,the treat-ment group was given Longxuejie enteric-coated tablets 4,3 times a day orally for 14 days.The blisters disappeared , pain relief,and recovery time of completely crusted ,treatment efficacy and neuralgia were compared between the two groups.Results In the treatment group,34 cases were cured,effective in 13 cases,total effective rate was 90.4%, which was significantly higher than 73.1% in the control group,the difference was statistically significant (χ2 =5.216,P<0.05).The blisters disappeared,pain relief,and recovery time of completely crusted in the treatment group were significantly shorter than those in the control group (t =3.216,5.432,4.643,3.654,all P <0.05).No postherpetic neuralgia was observed in the treatment group ,the incidence rate of postherpetic neuralgia of the control group was 13.5%,the difference was statistically significant (χ2 =4.875,P<0.05).Conclusion The Longxuejie combined with cobamamide in the treatment of herpes zoster in elderly patients has reliable effect ,fast improvement of clinical symptoms,a low incidence of postherpetic neuralgia ,it is worthy of clinical application .
2.Law Risk and Precaution of Pharmacist
China Pharmacy 2005;0(22):-
OBJECTIVE:To enhancement lawconsciousness and ability of self-protect of pharmacist.METHODS:Analysed the problem which occured in their work from the point of view of law and bring forward some advice.RESULTS &CONCLUSION:Pharmacist should do their work strictly according to the code for avoidance law risk.
3.Combined implantation of auto-limbal epithelium and amniotic membrance for treatment of symblepharon
Chinese Journal of Primary Medicine and Pharmacy 2008;15(9):1478-1479
Objective To observe the auto-limbal epithelium and amniotic membrance transplantation in treatment of Symblepharon.Methods Transplant with auto-limbal epithelium and aminiotie membrance including 23 patients (31eyes) some of them are recurrentcd pterygium,most of them are symblepharons.[ Result ] In the followup period for 3~12 months,Ocular surface reconstruction was successful in 26 of 31 eyes with symb|epharon,but five of them recurrented three months later with lees than pre-transplantation in degree.Conclusion The transplantation with auto-limbal epithelium and membrance transplantation is an effective method for the symblepharon.
4.Expressions and significances of sICAM-1 and sCD44v6 in peritoneal lavage fluid after laparoscopically assisted radical gastrectomy
Journal of International Oncology 2014;41(11):872-874
Objective To explore the expressions and significances of sICAM-1 and sCD44v6 in peritoneal lavage fluid after laparoscopically assisted radical gastrectomy,in order to evaluate the risk of laparoscopically assisted radical gastrectomy for the peritoneal plant transfer.Methods Ninety-two patients with gastric cancer were randomly divided into the control group and the experimental group.The control group was treated with open laparotomy and the experimental group was treated with laparoscopic surgery.The concentrations of both sICAM-1 and sCD44v6 were detected by enzyme linked immunosorbent assay.The positive rates of tumor cells in the two groups were compared.Results The expressions of sICAM-1,sCD44v6 in the two groups before operation had no significant difference (t =0.198,P =0.543 ; t =0.897,P =0.429).After operation,sICAM-1 and sCD44v6 levels increased significantly,but there was no significant difference between the two groups (t =0.766,P =0.312 ; t =1.092,P =0.129).The positive rates of tumor cells in the two groups before and after operation have no significant differences (x2 =0.789,P =0.287 ; x2 =0.912,P =0.198).Conclusion Laparoscopically assisted radical gastrectomy does not increase the expression of sICAM-1 and sCD44v6 in peritoneal lavage fluid and the risk of peritoneal metastasis.It is worthy of clinical poptdarization and application.
5.Clinical application of minimally invasive hip replacement
Chinese Journal of Tissue Engineering Research 2007;0(52):-
Artificial hip replacement is an effective therapy to eliminate hip pain,correct deformity and restore function.With population aging and improving of people life quality,artificial hip replacement has been widely conducted.Over the past 40 years,artificial hip replacement technique has rapidly developed,and minimally invasive technology presents development direction of future artificial hip replacement.Skilled operation experience and instrument application are two key factors to ensure surgery success.The minimally invasive technology arouses more attention from clinical doctors and patients due to minimal invasion,little blood loss and fast recovery.However,not all patients can undergo minimally invasive hip replacement.This paper summarized related studies on minimally invasive hip replacement in domestic,and discussed the indications,surgical approach,complications and prevention.
6.Soft and hardware design of automatic infrared handwash basin used in sterilization
Chinese Medical Equipment Journal 1989;0(03):-
This paper introduces primarily the design of hardware and software systems in infrared automatic handwash basin including the working process of the electric circuit. At the same time, in order not to act mistakenly suffering from exterior interference, the anti-interference function is added to the software, which is also the design technique of this software.
7.The influence of different concentration and centrifugal parameters on TEM sample preparation of Escherichia coli
Journal of Chongqing Medical University 1986;0(03):-
Objective:To investigate the influences of different OD value and centrifugal parameters on the ultrastructure of Escherichia coli in order to find out the best OD value,speed and time of centrifugation.Methods:According to orthogonal experimental designing principle,the E.coli with different OD600 values are divided into 9 different groups of centrifuge speed and time.The changes of E.coli morphology in each group at different OD600 value,centrifuge time and speed were compared under transmission electron microscope.Results:The different OD600 values and centrifugal parameters have little influence on the ultrastructure of E.coli,but when the OD600 value at 0.8,centrifuge time at 15 min,the cross-section ratio was significantly higher than other groups and was more suitable for observation.Conclusion:The best parameter to prepare the TEM samples of E.coli is under the OD600 value at 0.8 and centrifugation time at 8 minutes and speed at 5 000~12 000 r/min.
8.Development of transcranial magnetic stimulator and measurement of the magnetic field distribution
Chinese Medical Equipment Journal 2004;0(08):-
This paper introduces general guidelines for designing and constructing a magnetic stimulator (MS). These guidelines cover the theoretical concepts, hardware aspects and necessary components. RLC model producing the impulses in MS is focused on and the way to calculate the parameters of the model is presented. Some factors that influence induced magnetic field are discussed. Experiments are carried through with self-developed round coil and 8-shaped, and Tesla meter is used to detect the magnetic fields. The experiments data show that the distribution of the induced magnetic fields by the two coils are tailored to those of theoretical calculation adopted now. A simulation experiment to measure magnetic field in brain has been completed.
9.Practice and Exploration of the Guidance of Undergraduate Thesis in Preventive Medicine
Chinese Journal of Medical Education Research 2002;0(01):-
This paper briefly analyzes the main factors influencing the quality of the undergraduate thesis and points out that the guarantee of improving the quality is to strengthen the management of undergraduate thesis,improve overall capacity of teachers and train general capability and good attitude of students,etc.
10.Evaluation of obesity by body mass index,waist-hip-ratio and percentage body fat in adolescent
Chongqing Medicine 2014;(34):4637-4639,4642
Objective To compare the sensitivity of body mass index (BMI),waist-hip ratio (WHR)and percentage body fat (PBF)in the evaluation of the obese adolescents population,and find a more sensitive evaluation method.Methods In this study,2 045 adolescents were recruited in the city of Chongqing by using multiple-stage random cluster sampling,and they were identified as overweight or obesity on the base of BMI,WHR and PBF.Results There was significant difference among the detection rate of the three methods (P<0.05),the detection rate of PBF was the highest (12.9%),then BMI (7.2%)and WHR (6.0%).consistency test showed that the concordance of three methods was poor and Kappa (BMI and WHR)=0.199,Kappa (BMI and PBF )=0.441,Kappa (WHR and PBF)=0.187;comprehensive evaluation was chosen as the gold standard and compared with three meth-ods respectively by ROC curve,the analysis showed that area under curve (AVC):PBF(0.954)>BMI(0.918)>WHR (0.694). Conclusion The sensitivity of PBF and BMI was higher.Although the WHR sensitivity was lower,WHR is a good predictor asso-ciated for chronic diseases,which suggests that the development of appropriate adolescent WHR standard is necessary.