Objective To observe the intrapartum analgesic effect of Doula GT-4a pulse acting working station and the influence of it on labor and mother-to-child. Methods The observation group use intrapartum analgesia of 98 primigravida,and the control group was other 98 primigravida without intrapartum analgesia in the same delivery period. Two groups of gravidas were delivering by a high qualification of midwife while your cervix expand for 2 ～3cm. The observation group was given with GT-4a pulse acting working station. Results The analgesia VAS scores of the observation group,significantly different with that of the control group:The first stage of labor active period accelerated significantly,the second stage of labor was shortened. The cesarean section rate,the vaginal birth rate and the neonatal mild choking rate significantly declined compared with the control group. Though there were no statistical differences between two groups with the third stage of labor, postpartum hemorrhage, and neonatal severe choking rate.Conclusion The andlgesie effect of doula combined with GT-4 pulse theraphy for labor was good. It reduced cesarean section rate, improved maternity quality and had no adverse effects.

Amiodarone ; therapeutic use ; Anti-Arrhythmia Agents ; classification ; therapeutic use ; Arrhythmias, Cardiac ; drug therapy ; Child ; Clinical Trials as Topic ; Humans ; Hydantoins ; Imidazoles ; therapeutic use ; Imidazolidines ; Phenethylamines ; therapeutic use ; Piperazines ; therapeutic use ; Sulfonamides ; therapeutic use

Anti-Arrhythmia Agents ; therapeutic use ; Child ; Humans ; Tachycardia, Atrioventricular Nodal Reentry ; drug therapy ; Tachycardia, Ectopic Atrial ; drug therapy ; Tachycardia, Ectopic Junctional ; drug therapy ; Tachycardia, Supraventricular ; drug therapy ; Tachycardia, Ventricular ; drug therapy

Anti-Arrhythmia Agents ; adverse effects ; therapeutic use ; Cardiomyopathies ; drug therapy ; Drug Interactions ; Heart Defects, Congenital ; drug therapy ; Humans ; Long QT Syndrome ; drug therapy

OBJECTIVE: To investigate the clinical efficacy of nasal cellulose powder for the treatment of allergic rhinitis. METHOD: Thirty-six cases of patients with allergic rhinitis were randomly divided into control group and experimental group, 18 cases in each group. The control group was treated with physiological sea water and the experimental group with nasal fibrous powder. In 14, 28 days after drug evaluation in patients objective and subjective symptoms and signs improved nasal function (nasal airway resistance, the sense of smell) was compared. RESULT: The experimental group and the control group of subjective symptoms and objective nasal function were improved, but the experimental group was significantly higher than that of control group, the difference was statistically significant (P<0.05); Two groups of patients had no adverse reaction occurred. CONCLUSION The clinical curative effect of Nasal cellulose powder used in the treatment of allergic rhinitis is distinct, without adverse reactions, and is conducive to improving patient stuffy nose, nasal itching, sneezing and other symptoms and improve the patients quality of life, is worth clinical use.
Administration, Intranasal ; Cellulose ; therapeutic use ; Humans ; Quality of Life ; Rhinitis, Allergic ; drug therapy ; Treatment Outcome

Objective: To explore the infection of mycoplasma in the venereal diseases and information about their drug susceptibility. 　Methods: Materials from the 12 528 patients were cultivated and drug susceptibility made testing was made using the mycoplasma IST Kit.　Results: The results showed that 9433 of 12 528 (75.3%)were infected by mycoplasma, Uu infective rate 58.3 %(7 305 cases)was found significantly higher than Mh infective rate 3.0%(379 cases)and mixed infection of both Uu and Mh was 14.0%(1 749 cases,)P＜0.01. The no susceptible conditions were in turn that ofloxacine(50.5%), Erythromycine(41.9%), tetracycline(14.6%), doxycycline(4.7%), josamycine(2.9%), and pristinamycine(2.0%) respectively.　Conclusions:The results suggested that non-gonococcal genitourinary tract infection was firstly ureaplasma urealyticum, concentracted infection was at age 21-40 years. no susceptible stat of mycoplasma infection to drug was serious, so that susceptibility testing of mycoplasma had a important significance to clinical drug treatment.

Objective To investigate the changes of serum cytokines IL-2,IL-8,IL-10 and IFN-? in infants with cytomegalovirus hepatitis before and after ganciclovir treatment,and explore the underlying mechanisms of ganciclovir and the immunological changes in the development and progression of cytomegalovirus(CMV) infection.Methods CMV-IgM in the serum samples of 72 infants with identified cytomegalovirus infection were measured by enzyme-linked immunosorbent assay(ELISA).CMV DNA in blood was measured by quantitative PCR.CMV-IgM(+) and CMV DNA(+) were as observed group 1(35 cases,without hepatitis).Those with abnormality of ALT were regarded as observed group 2(37 cases,with hepatitis).Another 30 matched healthy infants were enrolled as healthy control group.Levels of serum IL-2,IL-10,IL-8 and IFN-? of each group were examined by ELISA,and CMV masculine hepatitis group were cured with ganciclovir(5mg/kg,i.v.,twice per day for 14 d,and then once per day for 14 d after a 7 days'interval),then the levels of above factors were examined again.Results The levels of IL-8 and IL-10 in observed group 1 were significantly higher than those in healthy control group(t=3.74,9.56;P0.05).After ganciclovir treatment,the level of IL-2 in observed group 2 was significantly higher than that in observed group 1(t=3.41,P0.05).The levels of IL-8,IL-10 and IFN-? were decreased significantly(t=6.52,7.24,14.23;P

Objective To observe the clinical effect of Herba Houttuyniae Injection in treating senile pneumonia and to explore its possible mechanism. Methods Sixty-five patients were randomly divided into two groups. The control group was treated with conventional western therapy (CWT), while the treatment group was treated with CWT plus Herba Houttuyniae Injection. The changes of serum cytokines, IL-2 and TNF-?, before and after treatment were observed. Results the total effective rate of treatment group is 94.3%, while that of the control group is 83.3%. The difference of the total effective rate between the two groups was significant(P

The fatty acid components and microviscosity of erythrocyte membrane in 39 type 2 diabetic patients with and without coronary heart disease(CHD) were examined by high-performance liquid chromatography (HPLC) and fluorescence polarization teachnique,and their relationship with insulin sensitivity index (ISI) and CHD were analyzed.The results showed that contents and composition of erythrocyte membrane arachidonic acid (AA,C20:4)were significantly lower in type 2 diabetic patients with or without CHD than those in control subjects (P＜0.01 and P＜0.05).The total fatty acids contents were also significantly lower in patients with CHD than those in normal subjects (P＜0.05).In patients with or without CHD,erythrocyte membrane microviscosity was significantly increased as compared with the controls (P＜0.01 and P＜0.05),and it was higher in diabetics with CHD than those without CHD (P＜0.05).AA contents of erythrocyte membrane was negatively correlated with microviscosity and positively correlated with insulin sensitivity index (ISI),while the microviscosities were negatively correlated with ISI in diabetics.AA,linoleic acid contents,microviscosity of erythrocyte membrane and ISI were all correlated with the incidence of CHD in diabetics.In diabetic patients,the fatty acid metabolic abnormality could cause the alterations of functions,structures and fluidity of erythrocyte membrane,thus may contributing to increased IRS and might be related to the incidence of CHD.

Objective:To develop a method of quantitative analysis of multi-components by single marker ( QAMS) for 4 kinds of saponins in spina date seed.Methods:Using jujuboside A as a reference, an HPLC method with a Kromasil C18 column (250 mm × 4.6 mm, 5 μm) was applied, the mobile phase was acetonitrile-0.1% phosphoric acid (30 ∶70), the flow rate was 1.0 ml · min-1 , the detection wavelength was 280 nm, the column temperature was 32℃and the injection volume was 20μl.The relative cor-rection factors among the four kinds of saponins were detected by QAMS .An external standard method was also used to determine the contents of the four saponins ( Wf ) , and the results were compared with those of QAMS ( Ws ) , and then the relative errors were calcu-lated between W f and Ws to evaluate the accuracy of QAMS , and the reproducibility was investigated as well .Results:The established QAMS was used to determine the four kinds of saponins in spina date seed , and totally 14 batches of spina date seed were determined . No significant differences were found out between the calculated values and the determined ones ( RSD<5%) .Conclusion:The vali-dated HPLC method shows the advantages of precision ,reproducibility and reliability .The established QAMS method is feasible , and suitable for the quality control of saponins in spina date seed .