The detection of renal disorders now involves a series of complicated diagnostic procedure such as radiologic pyelography, function studies in laboratory and others These add up to a painful, expensive, and time consuming experience for the patient, others may be spared the discomfort of unnecessary. Consequently, the development of methods for preliminary screening of patients is significant both with regard to the diagnostic information obtained and to the selection of those patients requiring complete urologic work up. In particular, a reliable screening test is important in establishing or ruling out renal pathology as an underlying factor in hypertension the finding of a disorder of one kidney in the hypertensive patient may be at indication for nephrectomy or other surgical measures of renal artery. A positive preliminary investigation warrants precise diagnosis by aortography and confirmation by individual renal clearance tests. Finally the primary objective of the screening test is the restriction of more exacting procedures such as aortography with its inherent risk of serious complications to the preoperative evaluation of a demonstrated lesions. The visualization of an internal structure by determining the spatial distribution of a gamma radiation-emitting isotope was started in 1950 when Cassen and his associates utilized newly developed scintillation counters to print mechanically the spatial distribution of radioactive iodine in the thyroid gland. Visual and functional informations referable to each kidney separately may be obtained by radioisotopes and tracer or by scanning techniques rapidly and without trauma. The renogram or tracing of the renal uptake and excretion of a labeled contrast medium is a clinically useful measure of renal vascularity, tubular cell function, and the patency of the upper urinary passage, and especially valuable as a screening test for the hypertensive patient with suspected unilateral disease of the kidney. Similarly, scanning images are achieving an important place in medical diagnosis of irregularities effecting the kidneys and other specific organs. Radioactive contrast media, such as I131 labeled diodrast, miokon, Urokon, or hippuran have been widely used for renal function studies. They are entirety unsatisfactory, however, for renal scintillation scanning because they are rapidly excreted by the kidneys without retention in the renal parenchyma in contrast but mercurial diuretics labeled with radioactive mercury are concentrated to a high degree in the renal tubular cells, chiefly in the cortex, prior to their appearance in the urine (Borghgraef 1956.MaAfee and Wagner 1960). Following the report of these letter writers, scintillation scanning of the kidney after the intravenous injection of Hg Neohydrin have been widely used in urological clinics for preliminary screening method of renal disease such as delineating the parenchyma of the kidney and space-occupying lesions by Krevitz, Berk, and others(Reley, Blahd, Mins, Morgan, Kuhl, Bender, Simmons, Blau, Kim) and remained several problems which is anticipated to improvements in resolution for further using of renal scan. The main purposes of this experimental study were: 1) to learn at which period of time it is best to visualize the renal parenchyma following the intravenous administration of Hg Neohydrin, 2) to learn the minimal detectable size of space-occupying lesion within the kidney phantom, and 3) to compare the renal scan with aortography and pyelography on various period of hydronephrosis for visualization of renal parenchyma, 4) to compare the renal scan with aortography on various degree of narrowing of the renal artery for visualization of renal parenchyma. MATERIALS AND METHODS: These experiments have been performed on 17 normal adult mongrel dogs anesthetized with intravenous injection of sodium amycal. Ofthese 3 dogs were used for determining the optimal time of visualization of the renal parenchyma. 8 dogs for the visualization of the parenchyma of hydronephrotic kidneys as created by partial ligation of the left ureter for the period of 1. 2. 3 and 4 weeks as devided in 4 groups, and 6 dogs were used for the visualization of the narrowed renal artery produced by partial obstruction to various degrees. A wax phantom of the kidney was utilized for the study of detectable minimal size of the intrarenal space occupying lesion, the phantom measures 12.5 X 6.2 X 3.5cm. All animals underwent renal scintiacan received 80 microcuri of Hg neohydrin intravenously, they were placed in a prone position and the study was carried out using a Nuclear-Chicago dual scanner with a 62-hole coarse focusing collimator containing a 3x3 inch sodium iodide crystal, the collimator was passed back and forth over the target are at a rate of 12-15cm, per minute. The scan usually required 30 minutes for complete of scan. The pyelography was performed in retrograde way with 30% diodrast injected through ureteral catheter and the amount of dye injected was adjusted to replace the urine from renal pelvis. The aortography was performed by transfemoral arterial catheterization technique as described by Seldinge. RESULTS: 1. The optimal opacification period of renal parenchyma after injection of Hg 203 neohydrin was found to range from 1 to 6 hours 2. By kidney phantom study it was demonstrated that the space-occupying lesion measuring 2cm. in diameter can not be detected on scan. While the lesion measuring 3cm, or more can be successfully visualized. 3. The effect of partial obstruction of the ureter upon the renal scintiscan for visualization of renal parenchyma was not. dependable, the renal scintiscan continued to appear up to at least the 2 weeks after partial obstruction of ureter whereas the retrogredepyelography and aortography showed the definite picture of hydronephrosis to various degree. 4. The renal scan is inconsistent in many instances of renal artery stenosis, the scan showed a diminished concentration of mercury in the kidney with stenotic main renal artery and complete failure of visualization of the renal substance in cases with completely obstructed renal artery. 5. It is possible to demonstrate the value and usefulness of renal scan of Hg neohydrin as a routine preliminary screening test for renal pathology, the alteration of the concentration of the mercury can might be expected to give additional information.
Administration, Intravenous ; Adult ; Animals ; Aortography ; Catheterization ; Catheters ; Contrast Media ; Diagnosis ; Diuretics ; Dogs* ; Humans ; Hydronephrosis ; Hypertension ; Injections, Intravenous ; Iodine ; Iodopyracet ; Kidney ; Kidney Pelvis ; Ligation ; Mass Screening ; Nephrectomy ; Pathology ; Prone Position ; Radioisotopes ; Renal Artery ; Renal Artery Obstruction ; Scintillation Counting ; Sodium ; Sodium Iodide ; Thyroid Gland ; Ureter ; Urinary Catheters ; Urography

Anthracnose symptoms severely occurred up to 50% on leaves of English ivy growing in greenhouses in Cheongwon area of Korea during disease survey in April, 2000. The symptoms developed as concentric spots with dot-like acervuli on leaves of the plant. A total of 24 isolates of Colletotrichum sp. were obtained from the spotted lesions and identified as Colletotrichum trichellum based on the morphological and cultural characteristics. Leaf spots similar to the original anthracnose symptoms were induced on the host leaves by artificial inoculation with the isolates of the fungus. This is the first record of C. trichellum causing anthracnose of English ivy in Korea.
Colletotrichum* ; Cultural Characteristics ; Fungi ; Hedera* ; Korea* ; Plants

Various measurements of cerebral ventricles in 50 normal newborn infants were performed, using ultrasonography. In transverse scan using linear array real-time scanner with 3 MHz transducer, the ratio of the distance between the falx and lateral wall of lateral ventricle to the hemispheric width was measured, In coronal scan through the anterior fontanelle using gray scale B-mode scanner with 5 MHz trand ucer, the ratios of the bifrontal diameter of the lateral ventricles to externally measured biparietal diameter and to head circumference were measured. Width of frontal horn at 5mm distance from the lateral end of frontal horn was also measured. In addition, the presence of cavum septi pellucidi was investigated in coronal scan. The result are as follows; 1. The lateral ventricle/hemispheric width ratio in transverse scan was 0.31±0.03. 2. Bifrontal diameter of lateralventricle/biparietal diameter ratio was 0.20±0.02 and bifrontal diameter of lateral ventricle/head circumference ration was 0.054±0.006. 3. Width of frontal horn was about 1mm and maximum width was 2 mm. 4. There was no significant difference in ventricular size between male and female, and among different gestation ages. 5. Cavumsepti pellucidi was found in 44 neonates (88%) among 50 normal neonates in coronal scan.
Animals ; Cerebral Ventricles ; Cranial Fontanelles ; Female ; Head ; Horns ; Humans ; Infant, Newborn ; Lateral Ventricles ; Male ; Pregnancy ; Transducers ; Ultrasonography

No abstract available.
Constriction, Pathologic*

In the past 8 years, strides have been made in the diagnosis and treatment of renovascular lession which induces hypertension. The most significant methods are differential renal function studies. excretory urography. redioactive renogrsm. and renal angiogram in the field of diagnosis and nephrectomy, by-pass graft, and endarterectomy including vein patch graft are the most significant in the treatment of renovascular hypertension. But simple excretory urography is. still of great help in screening large numbers of patients, and nephrectomy is used in one half the patients. These advances have been a natural outgrowth of early work by Gold blatt, Page. and others. The accepted and relatively we11-established theory is, of course. that reduced renal blood flow leads to renal ischemia which in turn stimulates production of Renin by the kidney. Renin is an enzyme which reacts with alpba-2 globulin to liberate the decapeptid angiotensin 1, Neither renin nor angiotensin I is a pressure substance, but still another enzyme rapidly converts angiotensin l to an octapeptide, angiotensin II, which is the most potent pressure substance known. CASE REPORT S. H. Chung. a 10 year-old Korean girl. was admitted with severe headache and unconsciousness of only 3 weeks. duration. B100d Pressure was 200/140. The urogram disclosed the left kidney measured l1 cm by 6 cm. With an appearance time of the contrast material at 5 minutes. while the right kidney measured 8.5cm by 4cm and contrast material did not appear until 2 hours and the pelvis. calycial systems were quite normal on both kidneys by retrograde pyelogram. Exploration revealed a smaller right kidney with almost total obliteration of the renal artery in dense fibrotic reaction. Nephrectomy was done and the b1ood pressure dropped. to l20/60 within t8 hours. The kidney substance appeared to be good and biopsy of the kidney revealed essentially normal renal architecture.
Angiotensin I ; Angiotensin II ; Angiotensins ; Biopsy ; Child ; Diagnosis ; Endarterectomy ; Female ; Headache ; Humans ; Hypertension ; Hypertension, Renovascular* ; Ischemia ; Kidney ; Mass Screening ; Nephrectomy ; Pelvis ; Renal Artery ; Renal Circulation ; Renin ; Research Report ; Transplants ; Unconsciousness ; Urography ; Veins

No abstract available.
Multiple Endocrine Neoplasia Type 2a* ; Multiple Endocrine Neoplasia*

No abstract available.
Multiple Endocrine Neoplasia Type 2a* ; Multiple Endocrine Neoplasia*

Pseudolipomatosis of the colonic mucosa has been recognized as a lesion featured with aggregations of gaseous spaces in the lamina propria, but its pathogenesis remains still unclear. This paper describes 6 cases of pseudolipomatosis occurring in the mucosa of stomach and large intestine, and the possible factors involved in gastrointestinal endoscopic procedure to produce gaseous entrapment in the lamina propria were analysed. All cases received either gastroscopy or colonoscpy before endoscopic biopsy. Mucosal tissues from both stomach and recto-sigmoid colon revealed multiple aggregations of small air-spaces resembling fatty infiltration in the lamina propria. Rarely were similar infiltrations within the muscularis mucosae and adjacent lymphoid follicles. Evidence for pneumatosis cystoides intestinalis or ulcerative colonic lesion was not associated, although one showed a small gastric ulcer nearby. Repeated inflations and deflations of the stomach or colon during the endoscopic procedure with miner mechanical trauma by instrument to the mucosa seem to contribute to its pathogenesis.

A case of a pleomorphic giant cell tumor of the pnacreas in a 54 year old man is presented. It produced hugecystic mass in the pancreatic area ultrasonographically. Also multiple loculated pancreatic pseudocyst andmultiple low densities in liver were presented in CT. Pathologically this case was a form of giant cell carcinomawhich was called as epulis-osteoid type, but the osteiod component in this case was not conspicuous.
Carcinoma, Giant Cell ; Giant Cell Tumors ; Giant Cells ; Liver ; Pancreas ; Pancreatic Pseudocyst

The measurement of the relative X-ray abssorption coefficient (CT No.) and the size of the lesion on CT ishighly valuable in the diagnosis of the certain disease, guide to treatment planning, and follow-up of patientunder treatment. But as the CT is a synthetic image, CT No. and size displayed in CT are greatly influenced byvarious factors such as KVp, slice thickness, scan time, CT No. of the surrounding, geometry of lesion in gantry,window width(W.W) and window level(W.L) etc. The study was performed ot evaluate the accuracy and error range ofthe CT measurement, including CT No. and size affected by various conditons using phantom model designed byauthor., Author also propose the optimum window width and window level for measurement of real size on CT. Theresulsts are as follows; 1. The CT No. of the lesion increases as the CT N. of surround increase if the CT No. ofthe lesion is below-100 H.U., while the CT No. of the lesion decreases as the CT No. of surround increases if theCT No. of the lesion is above 900 H.U. 2. The CT No. increases as photon influx (mAs) during scan increases. The higher the CT No. of the lesion, the greater the degree of increases are. 3. If the CT No. of the lesion is greater than that of surround, the size of the lesion increases as window level decreases. The narrower the windowwidth, the larger the difference between the maximum and minimum value of measurement and the steeper the slope ofchange is. 4. The window width affects the size if the measured size is sufficiently different from the true size.5. The greater the difference between the CT No. of the lesion and that of surround, the greater the differencebetweeen the maximum and minimum value of measurement. and as the CT No. of surround increases, the differencebetween the minimum and maximum value also increases. 6. The optimal window width and level for size measurementareas follows; Soft tissue
Diagnosis ; Follow-Up Studies