1.Continuous culture of recombinant mammalian cells producing hepatitis B virus surface antigen in stirred tank reactor equipped with a cell sedimentation column.
Suk Hoon HA ; Tae Wook HAHN ; Ree Ann YOO ; Wan Je PARK ; Hyun Su KIM
Journal of the Korean Society of Virology 1992;22(1):77-80
No abstract available.
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
2.Immunogenicity from polio/hepatitis B chimeric virus.
Tae Wook HAN ; Ree Ann YOO ; Suk Hoon HA ; Wan Je PARK ; Hyun Su KIM
Journal of the Korean Society of Virology 1992;22(2):111-117
No abstract available.
3.Cervical carcinoma with procidentia : a report of one case.
Jin wan PARK ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE
Korean Journal of Obstetrics and Gynecology 1993;36(10):3662-3665
No abstract available.
4.Cervical carcinoma with procidentia : a report of one case.
Jin wan PARK ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE
Korean Journal of Obstetrics and Gynecology 1993;36(10):3662-3665
No abstract available.
5.Leiomyoma of the vagina : report of a case.
Sang In CHOI ; Jin Wan PARK ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE
Korean Journal of Obstetrics and Gynecology 1993;36(12):3942-3945
No abstract available.
Leiomyoma*
;
Vagina*
6.Effectiveness and Safety of Regdanvimab in Patients With Mild-ToModerate COVID-19: A Retrospective Cohort Study
Susin PARK ; Nam Kyung JE ; Dong Wan KIM ; Miran PARK ; Jeonghun HEO
Journal of Korean Medical Science 2022;37(13):e102-
Background:
Regdanvimab has decreased the time to clinical recovery from coronavirus disease 2019 (COVID-19) and lowered the rate of oxygen therapy according to the results from phase 2/3 randomized controlled trial. More information is needed about the effects and safety of regdanvimab.
Methods:
We analyzed data for patients with high-risk mild or moderate COVID-19 being admitted to Busan Medical Center between December 1, 2020 and April 16, 2021. A propensity score (PS) matched analysis was conducted to compare patients treated with and without regdanvimab. The primary outcome was in-hospital death or disease aggravation which means the need for oxygen therapy (low- or high-flow oxygen therapy and mechanical ventilation) and secondary outcomes comprised the length of hospital stay and adverse reactions.
Results:
Among 1,617 selected patients, 970 (60.0%) were indicated for regdanvimab. Of these, 377 (38.9%) were administered with regdanvimab. Among a 1:1 PS-matched cohort of 377 patients each treated with and without regdanvimab, 19 (5%) and 81 (21.5%) reached the composite outcome of death, or disease aggravation, respectively (absolute risk difference, −16.4%; 95% confidence interval [CI], −21.1, −11.7; relative risk difference, 76.5%; P < 0.001).Regdanvimab significantly reduced the composite outcome of death, or disease aggravation in univariate (odds ratio [OR], 0.194; 95% CI, 0.112–0.320; P < 0.001) and multivariableadjusted analyses (OR, 0.169; 95% CI, 0.095–0.289; P < 0.001). The hospital stay was shorter for the group with than without regdanvimab. Some hematological adverse reactions were more frequent in the group without regdanvimab, but other adverse reactions did not significantly differ between the groups.
Conclusion
Regdanvimab was associated with a significantly lower risk of disease aggravation without increasing adverse reactions.
7.Two Cases of Convulsion Associated With Caprolactam.
Kuck Hyeun WOO ; Sang Je JUNG ; Wan Seup PARK ; Hea Ryeon SHIN ; Jin Seok KIM ; Sang Woo KIM
Korean Journal of Occupational and Environmental Medicine 1998;10(1):116-120
Two young men were seen with nausea, vomiting, dermatitis, seizure after two-four days of occupational exposure to caprolactam, a nylon fiber precursor. There were no significant results in laboratory test, brain CT, EEG except leukocytosis, hyperglycemia. Caprolactam has been shown to induce convulsive disorder in experimental animal studios and Tuma et al (1981) described that one worker acutely exposed to caprolactam developed generalized tonic-clonic seizure with leukocytosis. The coincidence of typical skin lesion with otherwise unexplained generalized tonic-clonic seizure in those young man strongly suggests that caprolactam was causal agent.
Animals
;
Brain
;
Caprolactam*
;
Dermatitis
;
Electroencephalography
;
Humans
;
Hyperglycemia
;
Leukocytosis
;
Male
;
Nausea
;
Nylons
;
Occupational Exposure
;
Seizures*
;
Skin
;
Vomiting
8.A case of bilateral multicystic dysplastic kidney diagnosed by prenatal ultrasonography.
Jong Hoon LEE ; Jae Whan KWAK ; Jin Wan PARK ; Tai Young HWANG ; hyun Ho KIM ; Goo Hwa JE
Korean Journal of Perinatology 1993;4(1):102-107
No abstract available.
Multicystic Dysplastic Kidney*
;
Ultrasonography, Prenatal*
9.Plasma Exchange in the Treatment of Cyclosporine Induced Hemolytic Uremic Syndrome Following Kidney Transplantaion.
Je Joon AHN ; Insoo RHEEM ; Jong Kwon PARK ; Jong Wan KIM
Korean Journal of Clinical Pathology 2000;20(6):604-608
Hemolytic uremic syndrome is characterized by a triad of clinical findings including microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. The precise etiology and pathogenesis of hemolytic uremic syndrome are not established by now. According to clinical reports, hemolytic uremic syndrome is associated with infection(bacteria, virus), connective tissue disease, malignancy, drug and pregnancy. Recently, many investigators have reported that cyclosporine induces hemolytic uremic syndrome. Cyclosporine is one of the immunosuppressants that are essential for kidney transplantation. We experienced one case of hemolytic uremic syndrome that developed after kidney transplantation receiving cyclosporine. A 43-yr-old woman with end-stage renal failure received kidney transplantation from her daughter. After operation, she received cyclosporine for immunosuppression and thrombocytopenia, microangiopathic hemolytic anemia and acute renal failure were developed. She was diagnosed as cyclosporine induced hemolytic uremic syndrome and plasma exchange was started with fresh frozen plasma. The plasma exchange was done 16 times and the clinical symptoms were improved. We present this case with review of literatures.
Acute Kidney Injury
;
Anemia, Hemolytic
;
Connective Tissue Diseases
;
Cyclosporine*
;
Female
;
Hemolytic-Uremic Syndrome*
;
Humans
;
Immunosuppression
;
Immunosuppressive Agents
;
Kidney Failure, Chronic
;
Kidney Transplantation
;
Kidney*
;
Nuclear Family
;
Plasma Exchange*
;
Plasma*
;
Pregnancy
;
Research Personnel
;
Thrombocytopenia
10.Prenatal diagnosis of twin reversed arterial perfusion sequence : a case report.
Jin Wan PARK ; Sang Cheon SEO ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE ; Won Ki LEE
Korean Journal of Obstetrics and Gynecology 1993;36(11):3798-3802
No abstract available.
Humans
;
Perfusion*
;
Prenatal Diagnosis*