Eight-year medical education has been run in some of the unversities in China,which has made some effective trials in personnel training mode according to the training purposes sent by Ministry of Education,but there still exists weaknesses in curriculum provision and reasearch training.This article briefly analyzed the major construction of the eight-year medical education and displayed several views.

AIM: To investigate the clinical safety and effectiveness of the two kind of bandage contact lenses: Senofilcon A (Johnson & Johnson Acuvue Oasys) and Balafilcon A ( Bausch& Lomb pure vision ) after laser - assisted subepithelial keratectomy (LASEK).
METHODS: Thirty - eight patients (76 eyes) who had undergone the LASEK were divided into two groups. One group of patients wore Balafilcon A, the other group of patients fitted with Senofilcon A. The lenses were worn continuously for 7d. This was a seven - day experience and the patients scored for the symptom of the eyes (sore eyes, foreign body sensation and tearing) on the third day and the seventh day. Both of the two groups of patients taken off the soft contact lens on the seventh day and let their vision and corneal staining checked.
RESULTS: The symptoms of eye sore and tearing of the two groups patients were different. The patients who wore the Senofilcon A were better. The pain of eyes were also different at 3 and 7d after surgeries(Z = - 4. 146, P =0. 000; Z= - 2. 814, P = 0. 005). The difference on tearing between the two groups at 3 and 7d after surgeries were significant ( Z = -2. 309, P = 0. 021; Z= -3. 276, P= 0. 001). There was no difference on sensation of dryness between the two groups at 3 and 7d after surgeries (Z= -0. 447, P=0. 655; Z= -0. 966, P = 0. 334). After the lenses were taken off, the visual acuity of patients wearing Senofilcon A was better ( t = 3. 800, P = 0. 001 ); corneal staining showed limited spots in 1- 2 quadrants with significant difference (Z= -2. 384,P= 0. 017).
CONCLUSION: The Senofilcon A ( Johnson &Johnson Acuvue Oasys ) and Balafilcon A ( Bausch& Lomb pure vision) bandage contact lenses are safe and effective after LASEK, and the former is better than the latter in epithelial regeneration.

Brain Diseases ; complications ; microbiology ; mortality ; Fatal Outcome ; Female ; Humans ; Middle Aged ; Otitis Externa ; complications ; microbiology ; mortality ; Pseudomonas Infections ; complications ; mortality

Objective:To discuss the effect of cochlear implant and hearing aid to voice quality.Method:Four groups of randomly selected 73 subjects were compared. The groups comprised: cochlear implant children, children using hearing aids, normal hearing children and deaf children with no hearing instrumention. The latter two groups were control groups. Each subject was required to phonate // about 3 s using 'voice assessment' to record the sound, and following voice acoustice variables were analysed: F0,SDF0,Jitter,Shimmer,NNE,HNR,SNR.Result:Voice F0 of children with cochlear implant was significantly lower that the other three groups(P<0.05);there were no significant difference between hearing aid group, normal hearing gourp, and deaf children group with no intervention(P>0.05);SDF0 of cochlear implant group and hearing aids group were significantly larger than the normal hearing group and deaf children group with no intervention(P<0.05),and the interaction of two factors(hearing and sex ) was close to the critical level of significance(P>0.05),which means that cochlear implant and hearing aid could have affected the SDF0 of female children more than those of male children. There were no significant difference among all the four groups about voice quality variables: Jitter,Shimmer,NNE,HNR,SNR.Conclusion:Cochlear implant and hearing aid mainly change the voice F0 and/or SDF0, and have no effect on the voice quality variables.

Objective To characterize the nasal resonance of children with spastic cerebral palsy by comparing it with that of ordinary school-age children.Methods The mean nasalance scores (MNSs) of 90 normal school-age children and 62 school-age children with spastic cerebral palsy were measured and compared.Results (1) Age has significant effects on the MNS of/a/,/i/and/m/ in ordinary children,but has almost no effect on the MNS of/u/.The MNS of/a/,/i/,/u/ and/m/ in children with spastic cerebral palsy does not change with age.(2) Sex only has a significant relationship with the MNS of/i/ in ordinary children,but does not significantly predict the other MNSs.(3) The MNS of/a/ of children with spastic cerebral palsy is significantly lower than that of ordinary children,and their MNS of/i/ and /u/ is significantly greater than those of ordinary children.Conclusions The MNS of /a/,/i/and /u/first increases and then decreases with age in ordinary children,while the MNS of/m/ increases gradually.Children with spastic cerebral palsy did not show the same trends and demonstrated a state of retardation of nasal resonance.Children with spastic cerebral palsy are more likely to display hypernasality than ordinary children.

Objective To establish a laboratorial test method of soaking the sample of hygienic protection beaded paint contacted with drinking water. Methods The samples of hygienic protection beaded paint were chosen to conduct the soak experiment, incontinuous soak of 4 times for 96 hours(exchange the soaking aqua every 24 hours), continuous soak of 4 times for 96 hours were conducted respectively, and then compared these experimental results with that which was obtained with the standard soak method(30 d,6 times) stipulated by The Examination Norm of Life Drinking Water (2001). Results The results of standard soak method(30 d,6 times)showed that chroma, smell, visible objects, volatility hydroxybenzene, arsenic, chromium, cademium, aluminium, lead, carbon tetrachloride, formaldehyde and etc. were all under the determination limit. Along with the increment of days of soak, the mean values of changed quantity of turbid degree, deliquescent total solid, pH value, mercury,and chlorpicrin concentration all showed a downtrend. When the incontinuous and the continuous soak of 4 times for 96 hours were finished, the results showed that chroma, smell, visible objects, volatility hydroxybenzene, arsenic, chromium, cademium, aluminium, lead, carbon tetrachloride, formaldehyde, and etc. were all under the detection limit. Along with the increment of days of soak,the mean values of changed quantity of turbid degree, deliquescent total solid, pH value, mercury, and chlorpicrin concentration all presented an decreasing trend, oxygen consuming content, pH value presented a fluctuant trend. The 4 times and 96 hours incontinuous soak procedure dissolved slightly more objects than the 4 times and 96 hours continuous soak procedure did. Conclusion The method of 4 times and 96 hours incontinuous soak should be recommended as the standard laboratorial method for soaking the hygienic protection beaded paint which will be contacted with drinking water.

Objective To observe the effects of Huoxue Xifeng Decoction (HXD) on endothelin-1 (ET-1) and nitric oxide (NO) levels in the blood and brain tissue of focal cerebral infarction (FCI) rats. Methods Forty male Wistar rats were randomized into 5 groups:sham-operation, FCI model and HXD-high, HXD-middle, HXD-low dose groups, with 8 rats in each group. The model of FCI rats was established by photo-chemistry method, and intragastric administration were continue 7 days before operation. HXD-high, HXD-middle, HXD-low dose groups were given HXD 20, 10, 5 g/(kg?d) respectively, and other groups were given the same volume distilled water. Blood and brain tissue samples were gotten 24 h after operation, and radio-immunity method was used to measure ET-1 level, spectrophotometric method was used to measure NO level. Results Compared with FCI model group, HXD decreased ET-1 level in plasma and brain tissue after infarction, and decreased NO level in the brain tissue, increased NO level in serum (P

Objective To investigate the cause, diagno sis and treatment of acute acalculous cholecystitis(AAC).Method 32 cases of AAC which were treated from 1990 to 2000 were analyzed retrosp ective ly.Results 25 cases were diagnosed by B-ultrasonograph ,th e positive rate of diagnosis was 88.0%(22/25),7 cases were diagnosed by CT,6 c ases were definitely diagnosed(85.7%).All of them underwent operations, cholec ystectomy was performed in 29 patients,cholecystostomy in 2, subtotal cholecyste ctomy in 1 .Of them 31 were cured and one died.Conclusions The cause of AAC is very complication, the preoperative diagnosis is difficult, it is easy to be misdiagnosed. Surgeon should pay more attention to AAC. B-ultra sonograph is the first choice of the diagnosis of AAC,CT can give a hand to diag nosis. The early operation resection is the most effective method.

Objective To investigate the short-term improvement of life quality in patients with obstructive sleep apnea hypopnea syndrome(OSAHS)after temperature-controlled radiofrequency ablation(TCFR).Methods Totally 70 patients with OSAHS were diagnosed by polysomnography(PSG)and received TCRF in our department.The Epworth Sleepiness Scale(ESS)and Calgary Sleep Apnea Quality of Life Index(SAQLI)were surveyed before and after the therapy.The results were followed up for six months after the operation.Results The pre-operative scores of ESS was correlated with body mass index(BMI),apnea hypopnea index(AHI),lowest saturation(LSaO2)and the scores of SAQLI(correlation coefficient:0.410,0.371,-0.441,and-0.411 respectively;all P