No abstract available.
Catheterization* ; Catheters* ; Hemothorax* ; Subclavian Vein*

No abstract available.
Atrioventricular Block* ; Myocarditis* ; Pancreatitis* ; Typhoid Fever*

Hereditary motor and sensory neuropathy is an unusual disease which is characterized by deformity of phe foot, acral sensory loss, decreare of deep tendon reflexes, enlargement of peripheral nerve and diminished motor conduction velocity. We report a case of hereditary motor and sensory neuropathy type I.
Congenital Abnormalities ; Foot ; Hereditary Sensory and Motor Neuropathy ; Peripheral Nerves ; Reflex, Stretch

No abstract available.
Cervix Uteri* ; Female

Authors experienced a 6-year-old patient who developed strabismus and amblyopia due to a facial hemangioma obscuring the visual axis. The patient recovered success fully strabismus surgery and occlusion therapy.
Amblyopia* ; Axis, Cervical Vertebra ; Child ; Hemangioma* ; Humans ; Strabismus*

PURPOSE: There is a predilection for subacute necrotizing lymphadenitis(SNL) in young Asian women. Few pediatric cases have been reported. This study was performed to evaluate clinical features of children with SNL. METHODS: We retrospectively analyzed clinical features of 23 cases of SNL under 15 years of age identified in Nowon Eulji Hospital from February 1995 to January 2002. Two cases were diagnosed by excisional biopsy and 21 cases by fine needle aspiration. RESULTS: The ages ranged from 14 months to 14 years(mean 8.1+/-3.8 years). The male to female ratio was 1 : 1.6. Ten cases(10/23) were diagnosed in 2000. The onset was more frequent in spring. The common presenting symptoms were neck mass(22/23), pain(12/20) and fever(8/18). Fever subsided within two weeks in seven out of eight and lymphadenopathy resolved within five months in 14 out of 15. The mean WBC count was 7,664+/-3,454/mm3. Elevated levels of ESR(10/ 12) and lactate dehydrogenase(5/6) and positive reaction for CRP(3/4) were frequent. Radiologically measured greatest diameter of the enlarged lymph nodes was less than 2 cm in 14 out of 15. One case occurred in a child with alopecia areata and one case with type 1 diabetes. Clinical outcomes were good in 23 cases. CONCLUSION: SNL should be considered in children with cervical lymphadenopathy regardless of fever or pain. SNL seems not rare in pediatric groups in Korea.
Alopecia Areata ; Asian Continental Ancestry Group ; Biopsy ; Biopsy, Fine-Needle ; Child* ; Female ; Fever ; Humans ; Korea ; Lactic Acid ; Lymph Nodes ; Lymphadenitis* ; Lymphatic Diseases ; Male ; Neck ; Retrospective Studies

Autoimmune hepatitis is a chronic necroinflammatory liver disorder of unknown cause associated with circulating autoantibodies and hypergammaglobulinemia. We report two pediatric cases of type 1 autoimmune hepatitis with normal serum immunoglobulin G levels who presented with fulminant hepatitis. The cases were associated with hereditary spherocytosis or atrioventricular septal defect. The first case was a 13-year-old boy with hereditary spherocytosis and gallstones. Acute cholecystitis and cholangitis developed during his clinical course and cholecystectomy, splenectomy and liver wedge biopsy were performed. The second case was an 8-year-old girl with repaired atrioventricular septal defect. In both cases, antinuclear antibody tests were positive and immunoglobulin G levels were normal. Interface hepatitis with moderate lobular inflammation were noted on their liver histology. They responded to the treatment of prednisolone and ursodeoxycholic acid.
Adolescent ; Antibodies, Antinuclear ; Autoantibodies ; Biopsy ; Child ; Cholangitis ; Cholecystectomy ; Cholecystitis, Acute ; Female ; Gallstones ; Hepatitis* ; Hepatitis, Autoimmune* ; Humans ; Hypergammaglobulinemia ; Immunoglobulin G* ; Immunoglobulins* ; Inflammation ; Liver ; Male ; Prednisolone ; Splenectomy ; Ursodeoxycholic Acid

We experienced one case of an unusual acute osteomyelitis of orbital margin, of which frontal, zygomatic and maxillary bone was involved in 10-month old infant. His clinical symptomes were similar to the acute osteomyelitis of superior maxilla but the primary site seemed to be in the frontal bone by history. We treated him with massive antibiotics and surgery (anterior approach). The causative organism was staphylococcus sureus, being very sensitive to penicillin. Also we reviewed the literatures of the orbital osteomyelitis comparing with thia case.
Anti-Bacterial Agents ; Frontal Bone* ; Humans ; Infant ; Maxilla* ; Orbit* ; Osteomyelitis* ; Penicillins ; Staphylococcus

The present study was designed to investigate the effects renin-angiotensin-aldosterone system (RAAS), endothelin (ET) and local natriuretic peptide (NP) system for glomerulopathy induced in the experimental bilateral ureteral obstructive rats. Sprague-Dawley male rats (200~220 g body weight) were bilaterally obstructed by ligation of the proximal ureters for 24 hours. Control rats were treated in the same ways, except that no ligature was made. The glomeruli were isolated from cortex by graded sieve methods, and the mRNA expressions of local renin-angiotensin system (RAS), aldosterone synthase (CYP11B2), endothelin-1 (ET-1) and NP system were determined by real-time polymerase chain reaction. Following the bilateral ureteral obstruction, the mRNA expressions of renin, angiotensin converting enzyme 1 as well as ET-1 were increased, while that of angiotensin converting enzyme 2 was not changed. The expressions of CYP11B2 and angiotensin II receptors were not changed. C-type natriuretic peptide (CNP) expression was increased, while its receptors (natriuretic peptide receptor-B) were not changed. We suggest that the upregulation of local RAS and ET play a role in the progressive glomerular injury, and that the enhanced CNP activity also plays a compensatory role in obstructive uropathy in the glomerulus.
Aldosterone Synthase ; Animals ; Endothelin-1 ; Endothelins* ; Humans ; Ligation ; Male ; Natriuretic Peptide, C-Type* ; Peptidyl-Dipeptidase A ; Rats* ; Rats, Sprague-Dawley ; Real-Time Polymerase Chain Reaction ; Receptors, Angiotensin ; Renin ; Renin-Angiotensin System ; RNA, Messenger ; Up-Regulation* ; Ureter* ; Ureteral Obstruction*

The present study was designed to investigate the protein expression of nitric oxide synthase (NOS) and guanylyl cyclase (GC) activity in ischemia/perfusion (I/R) renal injury in rats. Renal I/R injury was experimentally induced by clamping the both renal pedicle for 40 min in Sprague-Dawley male rats. The renal expression of NOS isoforms was determined by Western blot analysis, and the activity of guanylyl cyclase was determined by the amount of guanosine 3', 5'-cyclic monophosphate (cGMP) formed in response to sodium nitroprusside (SNP), NO donor. I/R injury resulted in renal failure associated with decreased urine osmolality. The expression of inducible NOS (iNOS) was increased in I/R injury rats compared with controls, while endothelial NOS (eNOS) and neuronal NOS (nNOS) expression was decreased. The urinary excretion of NO metabolites was decreased in I/R injury rats. The cGMP production provoked by SNP was decreased in the papilla, but not in glomerulus. These results indicate an altered regulation of NOS expression and guanylyl cyclase activity in I/R-induced nephropathy.
Animals ; Blotting, Western ; Constriction ; Guanosine ; Guanylate Cyclase* ; Humans ; Male ; Neurons ; Nitric Oxide Synthase* ; Nitric Oxide* ; Nitroprusside ; Osmolar Concentration ; Protein Isoforms ; Rats* ; Rats, Sprague-Dawley ; Renal Insufficiency ; Tissue Donors