1.Investigation and Analysis on the Attitude of Hospice Care Volunteer Service of Medical Students in Wenzhou
Chinese Medical Ethics 2017;30(6):747-749
Through the investigation on medical students' understanding of hospice care and their cognition and attitudes on voluntary services in hospices in Wenzhou,this paperconcluded that medical students accepted hospice care highly but knew little about it,and medical students were willing to participate in hospice care but actually rarely attended it.It is also suggested that universities should strengthen the propaganda and education of hospice care and volunteer service,joint efforts should also be given to expand the service opportunities and channels,and trainings should be provided to improve the development of hospice care volunteer services among medical students.
2.Effect of the levonorgestrel-releasing intrauterine device (Mirena) in the treatment of dysfunctional uterine bleeding
Clinical Medicine of China 2011;27(9):993-995
Objective To evaluate the efficacy and side-effects of the levonorgestrel-releasing intrauterine device (Mirena) in the treatment of dysfunctional uterine bleeding .Methods 45 cases of dysfunctional uterine bleeding diagnosed by pathology were installed with Mirena.The endometrial thickness by ultrasound hemoglobulin increase and pathologic changes of endometria were recorded before and 24 months after the installation.ResultsThe endometrial thickness before and after the insertion of Mirena were(15.6 ±4.2) mm and (3.2 ± 1.3)mmrespectively (P < 0.01) .Six months after the insertion of Mirena, patients' hemoglobulin was significantly increased from (97.6 ± 8.2)g/L to (123.7 ± 8.1)g/L (U = 2.26, P < 0.05) .After the installation of Mirena, patient experienced metrorrhagia.Conclusions Mirena is a device providing effective and continual therapy for dysfunctional uterine bleeding .It can not only significantly reduce the menstrual blood loss but also reverse the complex hyperplasia effectively.
3.Observations on the Efficacy of Warm Needling plus Palm Pressing Spine Reduction Technique in Treating Postpartum Thoracic Facet Joint Disorder
Shanghai Journal of Acupuncture and Moxibustion 2015;(11):1072-1075
Objective To investigate the clinical efficacy of warm needling plus palm pressing spine reduction technique in treating postpartum thoracic facet joint disorder.Methods Forty patients with postpartum thoracic facet joint disorder were randomly allocated to treatment and control groups, 20 cases each. The treatment group received warm needling plus palm pressing spine reduction technique and the control group, warm needling alone. The numeric pain rating scale (NPRS) score, the Oswestry Disability Index (ODI) score and the Quality of Life Scale score were recorded in the two groups before and after treatment and the clinical therapeutic effects were compared between the two groups.Results The total efficacy rate was 95.0% in the treatment group and 75.0% in the control group; there was a statistically significant difference between the two groups (P<0.01). There were statistically significant pre-/post-treatment differences in the NPRS score and the ODI score in the treatment group (P<0.01). There was a statistically significant pre-/post-treatment difference in the NPRS score in the control group (P<0.01). There were statistically significant post-treatment differences in the NPRS score and the ODI score between the treatment and control groups (P<0.01,P<0.05). There were statistically significant pre-/post-treatment differences in the SF-36 PF, RP, BP, VT, SF and MH scores in the treatment group (P<0.01,P<0.05). There were statistically significant pre-/post-treatment differences in the SF-36 PF BP, SF and MH scores in the control group (P<0.01,P<0.05).Conclusion Warm needling plus palm pressing spine reduction technique is an effective way to treat postpartum thoracic facet joint disorder.
4.Nerve growth factor promotes endogenous growth factor releasing from burn wounds
Lanping YE ; Yuanyuan WU ; Guangtong CAO
Chinese Journal of Tissue Engineering Research 2013;(28):5204-5208
BACKGROUND: Studies have confirmed that nerve growth factor can promote wound tissue to release al kinds of endogenous growth factors and growth factor receptors, which play a positive regulatory role. The nerve growth factor can promote cel proliferation and accelerate wound healing, thus making the wound healing developed from the passive waiting healing to active control healing. OBJECTIVE: To investigate the effects of local application of nerve growth factor on the expressions of transforming growth factor β1 and basic fibroblast growth factor in rat burn wounds. METHODS: Twenty-four adult Sprague Dawley rats were used in the study, and Ⅱ degree deep burn wound was made on the back of rats. Then, these rats were randomly divided into four groups. After burn wound debridement, the wounds were covered with gauzes containing 1, 2.5 and 5 μg/mL nerve growth factor solution and normal saline respectively. At 3, 5, 9 and 14 days after treatment, the wound healing time and percentage of residual wound were observed. Then, wound tissues were cut for histological examination, in order to detect the expressions of transforming growth factor β1 and basic fibroblast growth factor in wounds, as wel as the cel ular DNA cycle. RESULTS AND CONCLUSION: The wound healing time in the treatment groups was shorter than that in the control group, especial y in 5 ug/mL nerve growth factor treatment group (P < 0.01), and the percentage of residual wound in the treatment groups was less than that in the control group. The histological examination showed the number of nucleated cells in the superficial dermis of the treatment groups was significant increased when compared with that in the control group; the expressions of transforming growth factor β1 and basic fibroblast growth factor in the treatment groups at different time points were stronger than those in the control group, and the expressions at 5 and 9 days were stronger than those at 3 and 14 days; percentage of cells in S phase of the treatment groups was significantly increased, especial y in 5 mg/L nerve growth factor group (P < 0.01). The results indicate that local application of nerve growth factor can accelerate wound healing by increasing the expressions of transforming growth factor β1 and basic fibroblast growth factor, stimulating mitosis and promoting proliferation.
5.Clinical characteristics and treatment experience of burns in 46 diabetes patients
Yuanyuan WU ; Lanping YE ; Qiong LIU
International Journal of Surgery 2012;39(11):735-737
Objective To explore clinical features and therapeutic experience of burns of diabetes patients,for enhancing the curative rate of this diease.Methods The clinical data including the general condition and antishock,blood glucose controlling,surgery,symptomatic and supportive treatments of burns in 46 diabetes patients were analyzed.Results During three to seven days,the fasting plasma glucose of all patients dropped to below 10 mmol/L,and it dropped to below 8 mmol/L in 28 surgical patients.All patients were cured except one died in a bad way occurring multiple organ dysfunction syndrome,and the curative rate reached to 97.8%.Complications occurred in 26 cases and the incidence was 56.5%.Conclusion The burns in diabetes patients are very complicated.It is being effective to combine systemic with local treatments for the condition.
6.Validity and reliability of the simplified Chinese version of modified Barthel index for Chinese stroke patients
Yu MIN ; Yuanyuan WU ; Tiebin YAN
Chinese Journal of Physical Medicine and Rehabilitation 2008;30(3):185-188
Objective To study the validity,reliability and sensitivity of the simplified Chinese version of modified Barthel index (MBI) in evaluation of activities of daily living(ADL) of Chinese stroke patients. Methods Forty Chinese stroke patients (26 males and 14 females,aged 59.65±11.68 years) participated in the study.The duration of the disease averaged 21.20±19.44 days.All the patients were evaluated for three times with MBI.Barthel Index (BI) and the motor component of Functional Independence Measure (M-FIM)independently by twophysiatrists.Spearman correlation coefficients between MBI and Barthel index (BI),between MBI and M-FIM were used to test the validity of MBI.Intraclass correlation coefficients (ICC) were used to test both interrater and intra rater reliability of MBI.Sensitivity of MBl was analyzed with the Wilcoxon signed rank test and paired t-test.Results MBI was highly correlated with BI in each item and total score(r=0.816~1.000,P<0.01),and with M-FIM in total score(r=0.935~0.981,P<0.01).There were high reliability with MBI in the results collected by same assessor and different assessors(ICC=0.866~0.997).Furthermore,MBI was more sensitive than BI in majorities of its items and its total scores as well.Conclusions MBI has good validity and reliability as well as sensitivity in assessment of ADL of Chinese stroke patients.
7.Application of the repair in the facial skin and soft-tissue defects with local random flap
Donggang YAO ; Xuanfen ZHANG ; Yuanyuan WU
International Journal of Surgery 2014;41(7):451-453,封3
Objective To explore clinical efficacy of local random flap in reconstruction of facial skin and softtissue defects caused by lesions resection and injury.Methods Forty-six cases with facial skin and soft-tissue defects were cured by constructing and transplanting different local random flap that is designed according to parts,shapes and sizes of defect between July of 2008 and June of 2013.Results All the cases obtained satisfactory effects for full survivorship of flap,one-stage healing of wound,tiny scar and pigmentation,and good appearance by following up from 3 months to 6 months after operation.Conclusions Using local random flap in repair of facial skin defect could get satisfactoried functional and aesthetic efficacy,and it is worth being applicatied in the clinic.
8.Use of the stochastic frontier cost model in the technical efficiency evaluation of TCM hospitals
Weicheng WANG ; Wu ZENG ; Yuanyuan BING
Chinese Journal of Hospital Administration 1996;0(05):-
Objective To analyze the present situation of technical efficiency in TCM hospitals throughout the country, discuss the influencing factors causing inefficiency and propose corresponding suggestions. Methods The technical efficiency in 60 TCM hospitals in the country was analyzed using the stochastic frontier cost model for panel data and the influencing factors causing inefficiency were discussed using the multiple stepwise regression method. Results The average technical inefficiency was 22.59% and inefficiency showed an upward trend as the areas shifted from the eastern through the middle to the western regions. Five factors, including the utility rate of beds and the proportion of health technicians among the entire hospital staff, were statistically significant so far as the effect on the increase of the overall cost was concerned. Conclusion The stochastic frontier cost model for panel data is the best method for evaluating the technical efficiency in TCM hospitals. On the basis of the above analysis, suggestions for strengthening scientific management, improving the utility rate of resources and reducing unnecessary waste are put forward.
9.Content Determination of Polysaccharide in Pinellia Tuber
Jingfen WU ; Yuanyuan ZHANG ; Zhongqiang JI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(10):-
Objective To determine the content of polysaccharide of prepared pinellia tuber. Methods The content was determined by sulfuric acid-anthrone colorimetric method with wavelength at (624?1)nm. Results The content of polysaccharide was 2.533 mg/g in prepared pinellia tuber. The average recovery was 99.54% and RSD was 1.69%. Conclusion The methods was simple, steady and reproducible.
10.Influence of Acupuncture Treatment on Nitrogen Monoxide,Endothelin, Angiotensin and Rennin Levels of Acute Hypertension Rats
Xuesu WU ; Ming LI ; Yuanyuan LU
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(07):-
Objectives To explore the effects and mechanism of acupuncture treatment in emergent of acute hypertension by studying the acupuncture treatment on acute hypertension rats. Method The acute hypertension rat model was made by injecting adrenalin into the abdomen. After probing specific points, NO, ET-1, angiotensin and rennin levels were tested. Results Acupunctured for 30 minutes, the experimental group's diastolic pressure dropped and NO level rose, and these changes were statistically significant regarding those of the medicine control group. After the acupuncture treatment, the rennin level of the medicine control group and the experimental group were statistically different with the control group, but no significant difference was found between the medicine control group and the experimental group. Conclusion Probing Quechi, Taichong, Sanyinjiao and Neiguan may lead to the improved performance of the vessel endoderm, the rise of NO level and the decrease of angiotensin content, and consequently reduce the blood pressure of acute hypertension rats.