1.Evaluation of Diagnostic Immune Indices in Patients with Acute Glomerulonephritis & Nephrosis
Journal of Third Military Medical University 1984;0(01):-
Twenty-seven cases of acute glomerulonephritis and 6 cases of nephrolic syndrome were dynamically studied to determine the diagnostic value of the serum immune indices. In the acute stage of glomerulonephritis, the serum CH50 and C3 were markedly decreased and the extent of the decrease was closely related to the severity of the disease. If the course of the disease was prolonged, then the duration of the decrease of the serum immune indices was prolonged as well. Usually 40 days after the onset of the disease, CH50 and C3 of most cases returned to normal. It was found that the determination of serum CH50 and C3 are helpful in the differential diagnosis of acute glomerulonephritis,lipoid nephrotic syndrome and nephritic nephrosis, and it is also helpful to evaluate the severity of acute nephritis and make a prognosis.In cases of nephritis, the level of urinary bacteriolysin and CH50 reduced when the disease condition was improved. This change usually was in accord with the findings of routine urinary examination. It was considered that the urinary level of bacteriolysin is a good index of renal function. Serum IgG, IgA and IgM,the absolute number of lymphocytes, the transformation rate of lymphocytes, and the PHA skin test might also change during the improvement of the disease, but their diagnostic value is of no significance.
2.Effects of Compound Trace Element Mixture on Children's Growth and Development
Journal of Third Military Medical University 1983;0(04):-
147 patients under 7 years of age with maluntrition, anorexia, dysplasia, hypophrenosis and repeated attacks of cold were studied. The treated group consisted of 100 cases, and the control group 47 cases. Zinc and copper content of the hair was determined. The administration of the complex trace element mixture was found to be effective in improving appetite and sleep, promoting physical and mental development, correcting nutritional anemia, and bettering the athletic acility and immune functions of the patients in the treated group.
3.Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis
International Journal of Traditional Chinese Medicine 2016;38(5):417-419
Objective To evaluate the clinical effect of buccal administration of Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis. Method A total of 103 infantiles with herpetic stomatitis were randomly divided into a Kangfuxin group (51 cases) and a conventional group (52 cases). The conventional group received ribavirin aerosol, and the Kangfuxin group recived buccal administration of Kangfuxin Liquid based on the intervention of convertional group. All children were treated for 5 days. The white blood cell count (WBC) and the serum C-reactive protein (CRP) were determined. Result The total efficiency rate in the Kangfuxin group was significantly higher than that in the conventional group (94.1% vs. 78.8%,χ2=3.895, P<0.05). The healing time of oral ulcers (5.8 ± 1.3 d vs. 7.9 ± 1.5 d, t=10.715), body temperature recovery time (2.1 ± 1.1 d vs. 3.3 ± 1.5 d, t=4.623), and eliminating time of oral mucosal hyperemia and edema (4.3 ± 1.3 d vs. 5.3 ± 1.4 d, t=3.755) in the Kangfuxin group was significantly shorter than those in the conventional treatment group (P<0.01). The WBC (6.5×109 ± 2.2×109/L vs. 9.4×109 ± 2.3×109/L, t=6.537) and serum CRP levels (6.7 ± 1.2 mg/L vs. 9.7 ± 2.5 mg/L, t=12.686) were significantly lower in the Kangfuxin group was significantly lower than those in the conventional treatment group (P<0.01). Conclusions The total efficiency rate of buccal administration of Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis was higher than conventional treatment alone. And the remission time of symptoms of treatment group was shorter.
4.OSGi Key Technology and the Applying Research
Jiahui HU ; Sizhu WU ; An FANG
Journal of Medical Informatics 2015;(8):45-50
The paper summarizes and shares the current key technology of OSGi including the hierarchical model, the extended func-tion, the realization framework and the technical features.It illustrates OSGi's special advantages in service-oriented development of the modern information application system by giving examples and combining the three typical application fields, namely medical and health service, scientific research platform construction and remote information processing.
5.Determination of serum vitamin A level in primiparae and their neonates
Jiahui WU ; Xiangying KONG ; Jiasi BAI
Journal of Third Military Medical University 1984;0(01):-
Serum vitamin A level was determined in 75 healthy primiparae and their neonates and the correlation of serum vitamin A level with the levels of hemoglobin,ferrum rotein,feritin and zinc was analyzed.The serum vitamin A level was 3.06?1.03/imol/L in the mothers and 2.74?1.0?mol/L in the neonates,and it was higher when determined in summer than when determined in autumn but the difference was of no statistical significance.The rate of subclinical vitamin A deficiency was 27 % and 45.3% in the mothers and the neonates respectively.Serum vitamin lev- el was positively correlated with the levels of hemoglobin,ferrum and zinc(P
6.Application of 9.4 T 1 H-MR spectroscopy in determination of lactate in brain of mice with early acute hypoxia-ischeia injury and its significance
Yunping ZHANG ; Yangkang LI ; Chenyang LIU ; Jiahui ZHU ; Renhua WU
Journal of Jilin University(Medicine Edition) 2016;42(4):690-693
Objective:To explore the lactate metabolism in brain tissue of the mice with early acute hypoxia-ischemia injury,and to provide data support for 9.4T 1 H-NMR spectroscopy in detecting the lactate level clinically.Methods:Eighty Kunming mice were randomly divided into sixteen groups (0 s,20 s,40 s,60 s,2 min,4 min, 6 min,8 min, 10 min, 12 min, 14 min, 16 min, 18 min,and 20 min)according to the duration of hypoxia-ischemia (n=5).The changes of lactate levels were detected by 9.4T 1 H-NMR spectroscopy. Results:After the initiation of hypoxia-ischemia injury,the lactate level began to increase rapidly to the highest value of (6.89 ± 0.34)μmol·g-1 at 20 s,then started to decline quickly from 40 s to 2 min,and eventually decreased to a stable level of (4.85±0.36)μmol·g-1 until 6 min.Compared with control group,the levels of lactate in brain tissue of the mice in hypoxic-ischemic groups were increased (P <0.01).Conclusion:40 s of acute hypoxia-ischemia may be the lactate cerebral neuron threshold during the anaerobic glycolysis. 9.4T1 H-MRS can provide the exact time window for detecting the lactate metabolism.
8.Relation between the loneliness levels and cognitive deviation of medical students and its influ-encing factors
Xinling WU ; Peishan GUAN ; Heli WANG ; Jiahui ZHANG ; Lili ZHANG
Chinese Journal of Medical Education Research 2014;(3):313-316
Objective To examine the interrelation between the cognitive deviation and loneli-ness levels of medical students and its influencing factors. Methods Totally 220 medical students in grade two of one medical school were selected by method of cluster random sampling. The data of the research were obtained through cognitive bias questionnaire (CBQ) and emotional-social loneliness questionnaire. Interrelation between the cognitive deviation type and condition of emotional-social lone-liness of medical students were analyzed by Pearson product-moment correlation two-tailed test. Multi-ple stepwise regression analysis was conducted by taking score of emotional-social loneliness as de-pendent variable and score of CBQ as independent variable. Differences in cognitive deviation and loneliness levels between rural and urban students as well as between students from single child family and students from non single child family were analyzed by independent-sample t test. Results Neg-ative cognitive deviation of depression-distortion type was positively correlated with medical students' emotional isolation (r=0.161, P=0.021),social isolation (r=0.266,P=0.000), emotional loneliness (r=0.340, P=0.000) and social loneliness (r=0.385, P=0.000). The regression equation was: score of emotional-social loneliness=27.165+1.908 (depression-distortion)+0.836 (depression-non distortion).Students from non single child family had higher scores than students from single child family in the perspectives of depression-distortion”(P=0.017), social isolation(P=0.001), emotional loneliness(P=0.016), social loneliness(P=0.000). Rural students had higher scores in the above four perspectives than urban students(P<0.05). Conclusions Negative cognitive deviation levels of medical students is positively correlated with emotion and social isolation conditions and loneliness experiences. Regres-sion analysis shows that unhealthy cognitive disposition and thinking mode probably are one of the im-portant reasons leading to medical students' stress disorder. Students from single child family and rural area may experience social loneliness more deeply and students from single child family have obvious cognitive deviation.
9.Experimental study of rotational DSA on image deformation and measurement error
Gang PENG ; Yongming ZENG ; Yue LI ; Bin YU ; Jiahui WU
Chinese Journal of Medical Imaging Technology 2010;26(1):33-35
Objective To evaluate the image deformation and measurement error of rotational DSA by model experiment. Methods Five steel balls (diameter: 20 mm) were placed in a horizontal space of 30 mm, the middle of which was as the isocenter for rotational DSA acquisition. Another 5 steel balls (diameter: 10 mm) were placed in a vertical space of 30 mm with the same alignment for rotational DSA acquisition. The screen was divided into five regions and the morphological changes of the ball image were observed at each rotation angle. The experimental images of the left anterior oblique ball images at 20°, 40°and 60° among each two groups were selected and measured by automatic isocenter calibration and sphere calibration respectively, and compared with the actual diameters of balls to calculate the image magnification. Results Except the center one, other balls were of deformation at different rotation angles due to the distance to the detector leading to enlargement and reduction. With automatic isocenter calibration, only the diameter of the center ball corresponded with the actual one, the distance away from the center or the rotation angle was inversely proportional to measurement error (maximum magnification 12.42%).With sphere calibration, the measurement results in various regions at different rotation angle were basically the same, with smaller measurement error (maximum magnification 3.41%). Conclusion Placing the organ of interest in the center area can reduce image distortion in rotational DSA imaging. Selecting reasonable measuring technology according to the lesion location is helpful to control measurement errors.
10.Research on the Cognitive of Doctor-Patient Relationship among Junior Medical Students in Guangzhou
Xu LU ; Zhenlie CHEN ; Jiahui XUE ; Rusen ZHANG ; Fangqin WU
Chinese Medical Ethics 2017;30(7):827-831
Objective:To investigate the current situation of junior medical students'cognition on the relationship between doctors and patients,and to provide reference for medical students'medical education and medical education reform,Methods:Self-made questionnaire was adopted to investigate the cognitive status of doctor-patient relationship among junior medical students from three medical universities in Guangzhou.Results:Totally 41.04% of junior medical students had a basic understanding of doctor-patient relationship,and the degree of understanding of doctor-patient relationship is not different between junior and senior medical students (P > 0.05);76.62% of medical students got acquainted with the status of doctor-patient relationship mainly through the media;86.57% of junior medical students thought that the doctor-patient relationship was tense.The cognition of doctor-patient relationship between male and female students was similar (P > 0.05),and so wasit between freshmen and sophomores (P > 0.05).Male and female students had the same opinion on the future trend of doctor-patient relationship (P > 0.05).Many junior medical students were optimistic about the future doctor-patient relationship.Compared with freshmen,sophomore medical students were less optimistic about the future doctor-patient relationship (P < 0.05).Medical students mostly agreed on the causes of medical disputes (P > 0.05),believing that the main reason was the medical system.Conclusions:The cognition of the doctor-patient relationship profoundly affects the junior medical students as well as their choices of future employment and communication styles between patients and them,which may have important significance for avoiding medical disputes.Society,schools and the media should actively create a good atmosphere for the doctor-patient relationship.