Objective: To explore the influence of metacognitive group intervention on resilience of college students with social anxiety disorder. Methods: Forty-eight college students with social anxiety disorder were randomized into two groups. The control group (24 patients) received systemic desensitization, and the experiment group (24 patients) received metacognitive group psychological intervention. Social anxiety score, mental health and resilience score were compared before and after intervention of two groups. Results: The total scores of SCL-90 and the sub-scores of each dimension were significantly decreased after intervention, especially among the experiment group (P<0.05). No significant difference were found in the total score of SCL-90 and the scores of each factor at the last follow-up and after intervention in the experiment group (P>0.05). For control group, the total scores of SCL-90 and sub-scores of each dimension increased at the last follow-up compared with after intervention. Compared with before intervention, the LSAS and HAMA scores of the two groups significantly decreased, and the ER 89 score increased (P<0.05). There were no significant differences in the LSAS, HAMA, and ER 89 scores at the last follow-up and after intervention in the experiment group (P>0.05). For control group, the LSAS and HAMA scores at the last follow-up increased, and the ER 89 score decreased compared with after intervention (P<0.05). The LSAS and HAMA scores in the experiment group were significantly lower, and the ER 89 score was significantly higher, than those of the control group after intervention and at the last follow-up (P<0.05). Conclusion Metacognitive group psychological intervention can effectively improve resilience among college students with social anxiety disorder, helps reducing anxiety symptoms and promote social self-confidence and initiative.