1.Analysis of Current Situations and Influence Factors in TCM Research Projects of Nanjing Municipal Hospitals
Chinese Journal of Information on Traditional Chinese Medicine 2014;(7):4-7
ObjectiveBy reviewing TCM research projects in Nanjing municipal hospitals from 2006 to 2010 (eleventh five-year plan), this study aimed to recognize the existing problems, put forward corresponding solutions, and help Nanjing municipal hospitals improve scientific research level.Methods Through field investigations and interviews with experts, this study set 139 research projects from 2006 to 2010 in 10 municipal hospitals in Nanjing as study samples. ResultsDuring 2006-2010, current situations in TCM research projects of Nanjing municipal hospitals were as follows:the number of TCM research projects was small, the research level was low, and the fund was little. TCM research resources were unevenly distributed;the overall quality of TCM human resources were not high;talent structure was unreasonable;great differences existed among different types of hospitals.ConclusionsDuring the eleventh five-year plan period, there were significant differences between TCM research projects and WM research projects in Nanjing municipal hospitals, such as the differences in number, level, fund and project channel. The study proposed that TCM research materials should be rationally allocated, related mechanisms should be perfected, the industrial structure should be optimized, and the pace of training and introducing TCM research human resources should be quickened, with a purpose of making contributions to TCM development in Nanjing.
2.The application value of flupentixol-melitracen after percutaneous coronary intervention
Chinese Journal of Primary Medicine and Pharmacy 2016;23(6):880-883
Objective To investigate the short and long-term effects of flupentixol-melitracen after percu-taneous coronary intervention( PCI) .Methods 86 patients with coronary heart disease who would be given PCI were randomly divided into 43 cases of the study group and 43 cases of the control group.The control group was given conventional treatment after surgery, the study group was given flupentixol -melitracen on the basis of the control group.After one course,the mental status changes and short-term effect were observed.All the patients had been follow-up for 1 year to observe the occurrence of cardiovascular events.Results After one course,the HAMA and HAMD in the study group and the control group were (7.46 ±2.53) points and (15.74 ±3.16) points,(8.03 ± 1.97)points and (16.42 ±3.67)points respectively,which in the study group were lower than the control group (t=13.413,13.208, all P <0.01 ) .The total effective rate of the study group was 97.67%, which was higher than 81.40%of the control group (χ2 =6.081,P<0.05).During follow-up,the incidence rate of adverse cardiovascular events in the study group was 6.67%,which was lower than 42.86%of the control group (χ2 =9.564,P<0.05). Conclusion The flupentixol-melitracen can effectively improve anxiety and depression, improve the recent thera-peutic effect of PCI,reduce the incidence of cardiovascular events,which worthy of promotion after PCI.
3.Acupuncture and Moxibustion Therapy of Unilateral Neglect after Stroke
Chinese Journal of Rehabilitation Theory and Practice 2007;13(12):1196-1197
In accordance with the theory of traditional Chinese and Western medicine and clinical observance, the author explained the cause, mechanism and symptoms of the unilateral neglect after stroke, and summarized the way to treat the unilateral neglect with acupuncture and moxibustion therapy.
4.Normalization and individual therapy in treatment of inguinal hernia
International Journal of Surgery 2010;37(1):51-53
Since the first description of tension-free herniorrhaphy and the developement of prosthetic ma-terial for inguinal hernia, many techniques have come and gone. We should deploy the idea of evidence-based medicine and clinical practice guideline, according to the pathogenetie condition and medical condi-tion, in order to make the best treatment perseription for patient under the condition of nomudization.
5.An Improved Experimental Myocardial Ischemia Reperfusion in Rat Model
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To improve the way of establishing myocardial ischemia reperfusion rat model.[Methods]30 SD rats,quality(220?20)g,male,randomly split into normal model group and improved model group,improved established model ligation with a 0.6mm diameter line,and drawn after 30min.Compare such a method with normal model.[Results] In the context of keeping experimental stability,the reduced heart rate,wake time and survival rate of the way of improved established model respectively are(50?20)/min,(15?5)min,86.67%,but it is just(120?20)/min,(80?20)min,66.67% of the normal model group.[Conclusion]The improved myocardial ischemia reperfusion model offers significant superiority to the former one.
6.Effect of care bundle on preventing neonatal ventilator-associated pneumonia
Chinese Journal of Infection Control 2016;15(4):266-268
Objective To evaluate effect of care bundle on preventing neonatal ventilator-associated pneumonia (VAP). Methods Eighty neonates who met the inclusion criteria were selected and randomly divided into trial group and control group,two groups of neonates were both given routine nursing care,trial group were implemen-ted care bundle to prevent VAP on the basis of routine nursing care. Incidence of VAP,average length of neonatal intensive care unit (NICU)stay,and average hospitalization expense were compared between two groups of neo-nates.Results A total of 80 neonates were monitored,trial group and control group were both 40 cases. Incidence of VAP in trial group and control group were 21.21‰ and 35.04‰ respectively(P<0.05);average length of NICU stay in trial group and control group were (17.84±4.03)d and (23.50±4.81)d respectively(P<0.05);average hospitalization expense in trial group and control group were(26200.71 ±389.45)yuan and (38506.36±582.13) yuan respectively(P<0.05).Conclusion Care bundle can effectively prevent the occurrence of VAP,reduce the length of NICU stay,decrease hospitalization expense,and improve nursing quality and satisfaction.
7.Origin, existence form, and function of circulating microRNAs associated with cardiovascular disease
Journal of Medical Postgraduates 2015;28(10):1091-1094
MicroRNAs ( miRNAs) play an important role in regulating various life activities .It has been confirmed that circulat-ing miRNAs are new biomarkers for the diagnosis of many diseases and closely related with their occurrence and progression .In recent years, miRNAs are found to exist stably in blood and other body fluids in forms of being encapsulated in microvesicle or binding with proteins.Their origins, existence forms and functions have become a hotspot of research in this field .This article reviews the recent studies on the origin , existence form and function of circulating miRNAs associated with cardiovascular disease , aiming to provide some evidence for miRNAs as the biomarker and target of cardiovascular disease .
8.Advancing research on relationship between stromal cells and the development of tumor
China Oncology 2009;19(10):788-792
Stromal cells are one of the important components of tumor mieroenvironment, which plays an oncogenic role in tumorigenesis. Stromai cells and their products can transform adjacent tissues in the absence of pre-existing tumor cells by inciting phenotypic and genomic changes in the epithelial cells. The research on the tumor-associated-stromal cells will be benefit in clarifying the mechanisms of carcinogenic lesions and investigating more effective therapy methods.
9.Immunological regulation of mesenchymal stem cell
International Journal of Surgery 2008;35(5):318-321
Besides the haemopoietic stem cell, mesenchymal stem cell (MSC) is an adult stem cell in the marrow. It has the ability to self-renew, differentiate into various kinds of tissue and regulate the immunological system. MSC possess low immunogenicity. It shows the immunosuppressive ability in vitro and has function of inducing immune-tolerance. MSC suppress accrementition of T cell respone to the allotigen and mitogen and hinderes the development of cytotoxic T lymphocyte cell. In addition, MSC can influence antigen presenting cell, natural kill cell, B cell, and so on.
10.The valuable of expressed prostate secretion pH test in the diagnosis of chronic prostatitis
Chinese Journal of Primary Medicine and Pharmacy 2008;15(4):618-619
Objective To discuss the value of expressed prostate secretion(EPS) pH test in the diagnosis of chronie prostatitis. Methods EPS was obtained from 86 out-patients with chronic prostatitis, pH test and microscopy field being studied, prostate ultrasonography was performed after filling bladder. Results Mean pH of the EPS was (7.0±0.5), EPS-WBC was (20±10)/HP, and prostate ultrasonography positive rate were 63.9 % (55/86). pH of the EPS and the frequency of ultrasound abnormal ities were significantly correlated to the WBC in EPS.There was no correlation between age, disease process duration and the pH of EPS. Conclusion In chronic prostatitis, EPS-pH was positively correlated with the ultrasonography abnormalities and the WBC elevation of EPS, and EPS-pH test in the diagnosis of chronic prostatitis were meaning and value.