1.Thoughts on Constructing a Chinese Supervision System of Ethics Review on Biomedical Research Involving Human Subjects
Chinese Medical Ethics 1994;0(05):-
It is high time to regulate the Chinese medical ethics review system and construct a supervision system of medical ethics review.According to the guideline of WHO,models of supervision system of medical ethic review in certain developed countries,and national conditions,this paper proposes several countermeasures including perfecting related legal system,constructing certification system of ethics review committee,and formulating integrated contents and procedure of supervision.
2.An investigation on teaching effectiveness and students' feedback for preventive medicine
Tao GONG ; Wumei XIAO ; Nan NAN ; Long LI ; Nan WANG
Chinese Journal of Medical Education Research 2012;11(2):162-165
Objective To investigate the teaching effectiveness of preventive medicine and ask the students for feedback on the curriculum in order to reform the teaching methods.Methods Questionnaire survey.Sampling survey.Results 89.2% of students have realized the importance of preventive medicine.Respectively 16.4% and 7.5% of students have no interesting on the curriculum due to teachers'matter and students' idea that the course is uselessness for their major and future career.75.1% of students are interest in Nutrition and Food Hygiene,35.2% of students dislike Medical Statistics,and 45.3% of students think the most tough part is Medical Statistics.78.9% of students wish to have more practice lessons.30.5% of students do not ask teachers questions because of no communication with teachers after class.Conclusions Preventive Medicine is still ignored by a few students.The more tough the content is,the less interest the students have. Repeatedly emphasizing the importance of Preventive Medicine in medical education,adopting and combining with the community practical cases in class lectures and frequently communicating between teachers and students after class are suggested.
3.Effect of platelet-rich plasma on cellular proliferation and intracytoplasm calcium ion concentration of osteoblasts and tenocytes during the process of tendon-bone healing
Chinese Journal of Orthopaedic Trauma 2012;14(4):331-335
Objectlve To explore the effect of platelet-rich plasma (PRP) on cellular proliferation and intracytoplasm calcium ion concentration of osteoblasts and tenocytes during the process of tendon-bone healing. Methods We established a kind of indirect co-culture system using transwell chambers to co-culture osteoblasts and tenocytes.The cellular proliferation was carried out in following manners:single culture of osteoblasts versus single culture of osteoblasts plus PRP and co-culture of osteoblasts versus co-culture of osteoblasts plus PRP; single culture of tenocytes versus single culture of tenocytes plus PRP and co-culture of tenocytes versus co-culture of tenocytes plus PRP.The cellular proliferation rates were measured by CCK-8 test.The intracytoplasm calcium ion concentration of was measured by laser confocal microscopy and fluo-3/AM. Results The proliferation rates and fluorescence intensities in the co-culture groups without PRP were significantly lower than other groups ( P < 0.05).The proliferation rates and fluorescence intensities in the single culture groups without PRP were significantly higher than in the co-culture groups without PRP but significantly lower than in the groups with PRP ( P < 0.05).The proliferation rates and fluorescence intensities in the groups with PRP were significantly higher than other groups ( P < 0.05) but there was no significant difference between groups of the same cells ( P > 0.05).The intracytoplasm calcium ion concentrations were proportional to the proliferation rates. Conclusions During the process of tendon-bone healing,PRP has a potential not only to wipe off the depression effect of osteoblasts and tenocytes co-cultured indirectly but also to enhance the cellular proliferation rate to a higher level.At the same time the calcium ion concentrations will be elevated.
4.Invisible knowledge-based construction of values in medical staff
Chinese Journal of Medical Library and Information Science 2014;(2):32-34
It was pointed out in this paper that the nature of values was invisible knowledge by analyzing the rela-tion between values and invisible knowledge,and the measures were put forward for constructing the values in medi-cal staff in view of their value construction process and its influencing factors.
5.Tissue Doppler imaging to assess right ventricular function in hypertensive heart disease with normal pulmonary pressure
Chinese Journal of Ultrasonography 1993;0(01):-
Objective To evaluate right ventricular(RV) myocardial profile changes in hypertensive heart disease (HHD) with normal pulmonary pressure by pulsed wave tissue Doppler imaging(PW-TDI) technique,and to assess right ventricular function.Methods Group Ⅰ was normal control,20 cases,average age (54?7) years old,while group Ⅱ was primary hypertensive heart disease,20 cases,average age (58?8) years old.PW-TDI technique was used to measure the peak systolic,early diastolic,late diastolic velocities(Sm,Em,Am) of right atrio-ventricular ring,the ratio of Em/Am,right ventricular isovolume contracting time(RIVCT) and isovolume relaxation time(RIVRT).The systolic and early and late diastolic motorial amplitude(SD,DED,DAD) were measured by M-mode echocardiography.Results In groupⅡ: Em decreased [( 16.0? 2.7)cm/s vs ( 19.5? 3.4)cm/s,P
6.Brain natriuretic peptide: a potential indicator of cardiomyogenesis after autologous mesenchymal stem cell transplantation?
Journal of Zhejiang University. Science. B 2006;7(9):766-768
We observed in a pilot study that there was a transient elevation of brain natriuretic peptide (BNP) level shortly after the transplantation in the patient with ischemic heart failure, which is unexplainable by the simultaneous increase of the cardiac output and six-minute walk distance. Similar findings were observed in the phase I trial. We postulated on the basis of the finding of Fukuda in vitro that this transient elevation of BNP level against the improvement of cardiac function and exercise capacity might indicate cardiomyogenesis in patients after mesenchymal stem cell transplantation. Further study is warranted to verify the hypothesis.
Adult
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Aged
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Female
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Humans
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Male
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Mesenchymal Stem Cell Transplantation
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Middle Aged
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Muscle Development
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Myocytes, Cardiac
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physiology
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Natriuretic Peptide, Brain
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physiology
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Transplantation, Autologous
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Ventricular Remodeling
7.Analysis on Circulation Service in College and University Libraries
Journal of Medical Informatics 2009;30(7):82-83
The paper expounds the importance and role of circulation service in college and university libraries, how to do circulation work better is discussed from three aspects: scientific management of collections, creating a better environment and fully promoting the quality of staffs, thus to make library play a greater role in campus culture construction.
8.Epidemiology of dental trauma in children and adolescents
Chinese Journal of Emergency Medicine 2010;19(7):757-760
Objective To study the prevalence and distribution of dental trauma in children and adolescents. Method A total of 347 patients with the permanent anterior teeth injured aged from 6 to 25 years were treated and selected from July 2008 to June 2009. Data of gender, age, site of accident occurred, number of teeth injured, and location and type of injury were taken from the dental records. Results Of them, there were male 219, female 128, and the ratio of male/female was 1.7:1.0, The highest incidence of tooth injuries occurred a-mong children of 10 to 13 years old. The common site of dental trauma was school. The majority of dental casualties had one tooth (38.0%) and two teeth (38.0%) injured. Of all types of dental injury, subloxation (19.8%), and enamel and dentin fractures without pulpa involvement (18.7%) were the most seen ones. Con-clusions The dental trauma in children and adolescents is a major problem that can not be ignored, and should be given persistent attention to prevent.
9.Therapeutic Observation of Cluster Needling at Anterior Oblique Line of Vertex-temporal plus Speech Training for Motor Aphasia after Cerebral Infarction
Shanghai Journal of Acupuncture and Moxibustion 2015;(5):412-414
Objective To observe the clinical efficacy of cluster needling at the anterior oblique line of vertex-temporal plus speech training in treating motor aphasia after cerebral infarction.Method Forty patients with motor aphasia after cerebral infarction were randomized into a treatment group and a control group, 20 in each group. Both groups were given basic neurological treatment. In addition, the treatment group was intervened by cluster needling at the anterior oblique line of vertex-temporal plus speech training, while the control group was by speech training alone. After 4-week treatments, the speech function and communication ability were observed and the clinical efficacies were compared.Result The total effective rate was 90.0% in the treatment group versus 80.0% in the control group, and the difference was statistically significant (P<0.05). After treatment, the speech function score and Chinese Functional Communication Profile (CFCP) score were changed significantly in both groups (P<0.01). There were significant differences in comparing the speech function and CFCP scores between the two groups (P<0.01,P<0.05).Conclusion Cluster needling at the anterior oblique line of vertex-temporal plus speech training is an effective approach in treating motor aphasia after cerebral infarction.
10.Analgesic effect evaluation of dezocine in postoperative analgesia in abdominal surgery
Chinese Journal of Biochemical Pharmaceutics 2014;37(7):156-157
Objective To investigate analgesia of dezocine in abdominal anesthesia postoperative.Methods 80 cases (ASA I ~II)abdominal surgery under general anesthesia patients required postoperative analgesia,according to different postoperative analgesia drug,patients were randomly divided into 2 groups:dezocine group (group D),dezocine 0.6 mg/kg+ondansetron 4mg plus 0.9% sodium chloride to 100 mL,loading dose of intravenous patient controlled analgesia (PCIA);fentanyl group (group F),fentanyl 12 g/kg+ondansetron 4mg plus 0.9% sodium chloride to 100 mL,loading dose plus PCIA,recorded after 2,4,8,12,24,48 h visual analog scale (VAS)and Ramsay sedation score.Results The 2 groups were not statistically significant differences in VAS score and Ramsay score,and the incidence of adverse reaction of fentanyl group was significantly higher than that of dezocine group (P<0.01).Conclusion Dezocine group could provide analgesia safe and comfortable for patients after abdominal operation under general anesthesia.