1.Development of intelligent vision analysis system for urinary sediments
Chinese Medical Equipment Journal 2004;0(08):-
This paper introduces an intelligent vision analysis system for urinary sediments,which includes the function modules of mechanical,automatic adding sample and cleaning,images collecting,processing and intelligent vision recognition,system software and so on.It implements the course of adding sample,cleaning,images collecting,feature extraction,recognition and counting,self-learning automatically.
2.Role of extracellular histones in sepsis
International Journal of Pediatrics 2015;(4):371-374
Sepsis is a common desease with a high mortality in pediatric intensive care unit. The patho-genesis of sepsis remains unclear. Recent studies have found that extracellular histones play an important role in the incidence of sepsis. This review provides new ideas for the diagnosis and treatment of sepsis.
3.Off-Pump coronary artery bypass grafting: clinical study on myocardial protection
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(02):-
Objective: To compare the myocardial protection effect between off-pump coronary artery bypass(OPCAB)and on-pump coronary artery bypass. Methods: 70 patients were divided into 2 groups:off-pump coronary artery bypass(beating group,n=35), and cold blood cardioplegia solution group(cold group,n=35). There was no statistical difference in heart function, sex, age and weight before operation. Blood samples were taken for determine the serum concentration of creatine kinase MB isoenzyme (CK-MB) and troponin-T(cTnT) peri-operatively. Myocardial ultrastructure was also observed. Results: CK-MB, cTnT release in beating group during bypass and post-bypass was lower than that in cold group (P
4.Effects of Propofol on the Heme Oxygenase-1 Expression in Rats with H_2O_2-mediated Damage to Cultured Cardiac Myocytes
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong 2009;38(6):760-763
Objective To investigate the effect of propofol on the heme oxygenase-1(HO-1)expression in rats with H_2O_2-mediated damage to cultured cardiac myocytes.Methods Primary cultured new-born rat cardiac myocytes were divided into 8 groups:control,H_2O_2 group,low dose propofol (LP) group,middle dose propofol(MP)group,high dose propofol(HP)group,LP +ZnPP Ⅸ group.MP+ZnPP Ⅸ group and HP+ZnPP Ⅸ group.The cells in all groups were incubated for 6 h.The concentration of malondialdehyde(MDA),activity of superoxid dismuase(SOD),mitochondria and Caspase-3,and the expression of HO-1 were determined.Results As compared with H_2O_2 group,the HO-1 expression,and the activity of SOD and mitochondria were significantly increased(P<0.05,P<0.01),and activity of Caspase-3 and concentration of MDA was decreased(P<0.05)in MP and HP groups.As compared with LP,MP and HP groups respectively.the HO-1 expression and SOD activity were significantly decreased and the concentration of MDA increased in LP+ZnPP IX,MP+ZnPP Ⅸ and HP+ZnPP Ⅸ groups(P<0.05,P<0.01),while Caspase-3 activity was significantly increased in MP+ZnPP IX and HP+ZnPP IX(P<0.05,P<0.01).Conclusion Propofol can protect cardiac myocytes against H_2O_2-mediated cytotoxicity in a dose-dependent manner,and increase the HO-1 expression,which may partly mediate cytoprotective effects of propofol.
8.Treatment of postoperative gastrointestinal fistulas in patients with severe acute pancreatitis
Chinese Journal of General Surgery 1993;0(02):-
Objective To explore the means of treating postoperative gastrointestinal fistulas in patients with severe acute pancreatitis(SAP). Methods A retrospective study was carried out on the clinical data of 28 cases of postoperative gastrointestinal fistulas(PGF) in patients with severe acute pancreatitis admitted in our department between 1996 and 1999.Results The amount of drainage decreased significantly by using somatostatin(SS) and growth hormone(GH). All the patients were recovered, the average disappearred time of the fistula was (52?16) days(24~227 days).85.7% of the fistula were cured by non operative treatment.Conclusions Non-operative treatment is suitable to most of SAP patients with PGF. SS and GH can accelerate the healing of gastrointestinal fistulas.
9.Distribution and Drug Resistance in 251 Coagulase Negative Staphylococcus Strains
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To investigate the antibiotic resistance status in coagulase negative staphylococcus (CNS) strains and provide the scientific evidence for the reasonable use of antibiotics. METHODS The drug resistance of 251 strains of CNS was ananlyzed. RESULTS The detection rate of methicillin-susceptible coagulase-negative Staphylococcus(MSCNS) was 12.75% (32/251), while that of methicillin-resistant coagulase-negative Staphylococcus (MRCNS) was 87.25%. The drug-resistance rate of MRCNS was higher than that of MSCNS. Vancomycin resistant and intermediate strains had not been detected. CONCLUSIONS Laboratory should monitor the drug resistance well and update in time to offer the evidence for the reasonable use age of the antibiotics.
10.New process in the treatment of acute traumatic coagulopathy
Journal of Chinese Physician 2016;18(2):314-316
Acute traumatic coagulopathy (ATC) attacks suddenly with a rapid progress and has an extremely highly mortality.Of late years more and more relative studies have made a great progress on the pathogenesis,diagnosis and treatment of ATC.However,there are currently no medical guidelines for ATC.There are still some problems such as nonstandard treatment,outdated concept and so on in clinic.Based on the latest research progresses home and abroad,this paper expounds emphatically the first-aid and treatment of ATC in order to bring helps to the clinical doctors.