There are about 170 kinds of medical plants of Commelina all over the world.Experimental studies showed that the main chemical compositions in the plants included alkaloids,flavonoids,terpenes,and sterols etc.Plants of commelina,especially commelina communis,have pharmacological activities of antibacterial,antiinflammation,resisting-oxidation,lowering-glycemia,relieving-pain and stopping-cough etc.It is necessary that their pharmacological effects and chemical compositions are further developed and investigated systematically.

Peroxisome proliferator-activated receptors(PPAR) are ligand-activated nuclear transcription factors which regulate the expression of many genes.Numbers of researchs indicate PPAR exert anti-inflammatory activities by inhibiting the expression of inflammatory singal transcription passage such as NF-?B,AP-1,STAT,meanwhile preserve from acute lung injury.This review will focus on structure of PPAR and their ligand and activity regulation and antiinflammation mechanism of action and protection to acute lung injury.

Objective To observe the clinical effect of warming needle moxibustion and acupuncture therapy for knee osteoarthritis of deficiency cold type , and explore effective ways to treat knee osteoarthritis of deficiency cold type .Methods Eighty three patients with cold knee osteoarthritis in our hospital from May 2010 to April 2014 type were randomly divided into warming acupuncture group (42 ca-ses) and control group (41 cases).Patients in warming acupuncture group were given the treatment of warming needle moxibustion meth -od, and those in the control group were given the treatment of simple acupuncture .After three courses of treatment , the treatment effect and compliance of two groups during treatment was closely obserred .Results Efficiency of warming acupuncture group was 95.0%.It had significant difference compared with 85.7%in the control group (P<0.05).Treatment compliance rate of warming acupuncture was 95.2%, which was significantly higher than 85.4%of control group (P<0.05).At the end of each treatment period , Joint pain relief degree of warming acupuncture group patients were significantly higher than those in control group (P<0.05), and joint pain degree of warm acupuncture group reduced significantly after a course reduced compared with it before a course (P<0.05).Conclusion The cur-ative effect of warm acupuncture in the treatment on knee osteoarthritis of deficiency cold type is better than that of simple acupuncture therapy.It is worth in clinical application .

Objective:To explore the effect of cholecystokinin on electricity activity of gastric distention related neurons in the nucleus of tractus solitarius.Methods: The effects of gastric distention and intravenous CCK on electricity activity of gastric distention related neurons in the nucleus of tractus solitarius were investigated in urethane anesthetized rats.Results:Intravenous CCK could obviously influence the spontaneous activity of gastric distention related neurons in the nucleus of tractus solitarius.Intravenous CCK could increase the discharge of gastric distention(GD)excited neurons(9/14)and decrease the discharge of GD inhibited neurons(5/14) in NTS.Howerer,the effect of CCK on gastric distention-induced discharge of GD related neurons was always inhibitory.Conclusion:Circulating CCK and gastric distention have both excitatory and inhibitory effects on the electricity activity of gastric distention related neurons in NTS,but the effect of CCK on gastric distention-induced discharge of GD related neurons is inhibitory.The effect of gastric distention on spantenous discharge of neurons in NTS is similar to circulating CCK.

Objective:To discuss the clinical value of pelvic devascularlization in prevention and treatment for gynaecology and obstetrics refractory hemorrhage.Methods:To analyze retrospectively the effect of 15 cases of obstetrics,2 cases of preventing hemorrhage,5 cases of gynaecology refractory hemorrhage,all of these are treated by pelvic devascularlization.Results:There are 2 cases of placenta praevia of central type,(hemostatic scrap interdict uterus artery blood flow,volume of hemorrhage

Objective To explore the influence of Dan'e-Fukang soft extract on anxiety and depression of edometriosis patients.Methods 83 patients with endometriosis were randomly divided into a treatment group,treated with Dan'e-Fukang soft extract and a control group,treated with Gesrtinone capsules.Gynecological examination,pelvic B-mode ultrasonopgraphy,liver function,kidney function and CA 125 were detected before and after the treatment.The alteration of dysmenorrhea pain,menstrual blood volume,and adverse reactions were observed.Self-rating Depression Scale (SDS) and self-rating Anxiety Scale (SAS) were used to test the patients after treatment.Results ① Endometriosis effective rate of the treatment group and the control group were 95.35％ and 100.0％ respectively.② SAS and SDS score of the treatment group were (48.56± 5.39) and (50.35 ± 6.76) respectively before treatment,(33.43 ± 4.52) and (35.54± 4.68) respectively after treatment.The score of control group were (46.92±6.35) and (53.41 ±7.00) before treatment (37.56±5.64)and (42.87± 5.79) respectively after treatment.The scores had no significances between the two groups before the treatment,but had significant difference after the treatment(P＜0.05).Conclusion Dan'e-Fukang soft extract has exact effects on endometriosis,and its effects on mood are partly independent from endomet riosis.

On the one hand, diabetes mellitus and psychological diseases can affect each other to bring about many bad consequences, such as insomnia. On the other hand, insomnia can also cause diabetes mellitus and psychological diseases. TCM also has some knowledge on the relations between them. The present paper is a general survey of recent studies on this field in China and abroad.

Objective To evaluate the clinical symptoms,therapy and prognosis of cardiogenic cerebral embolism(CCE).Methods Clinical date of 72 patients with CCE were analyzed.Results 56 cases of CCE were over 60 years old men,which take up 77.8% ;non valvar atrial fibrillation (NVAF) 83.3% ;left medial cerebral arteria embolism 52.8% ;embolism hemorrhagic 19.4% ;death takes up 8.33%.Conclusion Atrial fibrillation is the main cause of the CCE,prognosis of CCE is not good,anticoagulant is an effective treatment for atrial fibrillation patients,it can avoid cerebral embolism.

Objective:To investigate the clinical curative effect of focused ultrasound on vulval condyloma acuminatum.Methods:108 cases of vulval condyloma acuminatum confirmed by pathology were randomly divided into two groups with the same number in each group:ultrasound group and laser group(controls).54 cases in the ultrasound group were treated with focused ultrasound,other 54 cases underwent laser treatment.The symptoms and local changes of the patients were observed before and after the treatment.The warts were obtained for pathological analysis to evaluate the efficacy of focused ultrasound treatment.Results:1.In the ultrasound group,49 cases recovered after the first treatment,the efficacy rate was 90.7%(49/54),while in the laser group,the rate was 68.5%(37/54).There was significant difference between the two groups(P

Objective:To investigate the effect of horticultural therapy on postpartum posttraumatic stress disorder and medical coping method of perinatal depression patients and to provide reference for perinatal depression patients.Methods:A total of 124 perinatal depression patients in Xuchang Maternity and Child Health Hospital from January 2018 to December 2019 were divided into experimental group (62 cases) and control group (62 cases) by random digits table method. The control group received routine nursing, while patients in the experimental group carried out horticultural therapy based on the outine nursing. Before and after intervention, the depression levels were assessed by Postpartum Depression Screening Scale (PDSS), posttraumatic stress was evaluated by Posttraumatic stress CheckList-Civilian version (PCL-C), medical coping method was assessed by Medical Coping Method Questionnaire (MCMQ), respectively.Results:There was no significant difference in the score of PDSS, PCL-C, MCMQ before intervention between the two groups( P>0.05). After intervention, the scores of sleeping/eating disturbance, anxiety/insecurity, emotional lability, cognitive impairment, guilt/shame, contemplating harming oneself, and total PDSS were (8.95 ± 1.37), (9.53 ± 1.57), (10.02 ± 0.79), (7.78 ± 1.43), (9.36 ± 1.81), (7.14 ± 1.56), (61.86 ± 3.78) points in the experimental group, significantly lower than those in the control group (10.11 ± 1.45), (10.96 ± 2.41), (10.81 ± 1.43), (8.61 ± 1.67), (10.35 ± 1.64), (7.84 ± 1.72), (67.93 ± 5.12) points, the differences were statistically significant ( t values were 2.320-7.239, P<0.05). The scores of arousal symptoms, avoidance/numbing, re-experiencing symptoms and total PCL-C were (7.12 ± 0.81), (9.12 ± 1.61), (5.42 ± 1.09), (21.66 ± 2.03) points in the experimental group, significantly lower than in the control group (7.93 ± 1.32), (9.81 ± 2.07), (6.16 ± 1.35), (23.89 ± 2.37) pionts, the differences were statistically significant ( t values were 2.001-5.463, P<0.05). The MCMQ scores in avoidance and yielding were (10.78 ± 2.14), (9.81 ± 2.74) points in the experimental group, significantly lower than in the control group (11.89 ± 2.78), (10.86 ± 2.66) points; their score of facing were (17.39 ± 2.59) points in the experimental group, significantly higher than in the control group (15.95 ± 2.63) points, the difference was statistically significant ( t values were 2.413, 2.971, 2.085, P<0.05). Conclusions:Horticultural therapy can alliviate depression, decrease postpartum posttraumatic stress disorder and promote medical coping method of perinatal depression patients.