Objective To investigate the fasting plasma insulin (FINS) and free fatty acid (FFA) in overweight or obesity patients with type 2 diabetes mellitns (T2DM) Methods 263 patients of T2DM were selected and divided into normal weight group(n = 108) and overweight or obesity group(n = 155) according to body mass index (BMI) , FINS level was detected by chemiluminescence method , and FFA level by colorimetry. 72 subjects without T2DM were taken as controls. Results FINS [(6.18±1.86) mIU/L vs (4.60±2.58) mIU/L, P < 0.01)] and FFA [(0.58±0.25) mmoL/L vs (0.35±0.14) mmoL/L,P < 0.01)] in T2DM group was significandy higher than that of control group. FINS in overweight or obesity group [(7.20±1.99) mIU/L] was higher than that in normal weight group[(5.31±1.21) mIU/L] and control group[(4.60±2.58) mIU/L] (P <0.01). In T2DM group,FiNS was positively correlated with duration(r =0. 334,P <0.01) ,BMI(r =0. 532,P <0. 01) and diastolic pressure (DBP) [r =0. 342 ,P <0.01). Conclusion The FINS level in overweight or obesity patients with T2DM is significantly higher compared to T2DM with normal weight T2DM,and the FFA level in patients of T2DM is significantly higher increased compared to control group,both of which participate in insulin resistence as well as the occurrence and development of T2DM.

Objective To analyze the curative effect of acupoint catgut-embedding therapy for PCOS patients of obesity.Methods 60 PCOS patients are randomly divided into an experimental group (acupoint catgut embedding group)and a control group (acupuncture group),with 30 cases in each group.Observe such indexes of each patient as weight,lumbar,BMI and menses before and after treatment.Results The two methods are significantly effective to reduce weight and improve the menstrual disorder,with no statistically significant difference(P＞0.05).Conclusion Acupoint catgut-embedding therapy is an effective method to treat PCOS of obesity.

Fractal is a new conception.In this paper some knowledge of fractal is first described.Our research work of fractal application in Doppler ultrasound technique is reported.

The restriction between distance and velocity measurement in medical Doppler ultra-sound is first proposed in this paper.The reasons resulting in this restriction are also analysed.Then our method to estimate blood flow velocity profile is introduced,in which the restriction is avoided.The discussion of this restriction in medical Doppler ultrasound and the method to detect blood flow velocity profile are finally presented.

Objective To evaluate the efficacy and safety of target-controlled remifentanil infusion combined with cervical plexus block for anterior cervical decompression surgery.Methods Twenty ASAⅠ or Ⅱpatients aged 30-64 yr undergoing anterior cervical decompression were studied.After a succegsful cervical plexus block,TCI of remifentanil was started at a target plasma concentration(CP)of 1.5 ng/ml 5 min before operation.The remifentanil CP was adjusted according to the patient's response to surgical stimulation and increased or decreased by 0.2 ng/ml each time until Ramsay sedation score reached 2-3 or verbal pain score(VPS)reached 0-1.TCI of remifentanil was discontinued 5 min before the end of surgery.MAP,HR,SpO2,BIS,Ramsay sedation score and VPS were monitored and recorded before cervical plexus block(To,baseline),at 10 min after cervical plexus block(T1),5 min(T2),30 min(T3)after skin incision,when the response to tracheal traction was significant during operation(T4)and at the end of operation(T5).The highest remifentanil Cp and the side effects such as respiratory depression,muscle rigidity,nausea/vomiting and pruritis that occurred were recorded.Remits MAP,SpO2 and BIS were not significantly changed during operation as compared to the baseline values at T0.HR was significantly increased at T2 as compared with the baseline.The Ramsay score reached 2-3 and the VPS reached 0-1 in the majority of patients in group R.No marked side effects were detected during TCI of remifentanil.The remifentanil CP ranged between 1.5-5 ng/ml and the mean CP during operation was(3.4±1.0)ng/ml.Conclusion TCI of remifentanil of low concentration combined with cervical plexus block can safely and effectively induce awake analgesia in patients undergoing anterior cervical decompression surgery.

Objective To investigate the effects of psychological stress on small intestinal bacteria and mucosa in mice, and to explore the relationship between small intestinal disfunction and small intestinal bacteria and mucosa under psychological stress. Methods 48 mice were randomly divided into psychological stress group and control group. An animal model with psychological stress was established lodging the mice and a hungry cat in separate layers of a two-layer cage. D-xylose levels in plasma were measured for estimating the damage degree of small intestinal mucosa. A section of the proximal small intestine was harvested under sterile condition and processed for quantitation for aerobes (Escherichia coli) and anaerobes (Lactobacilli). The quantitation of bacteria was expressed as log10[colony forming units/g]. Results D-xylose concentrations in plasma in psychological stress mice were significantly higher than those in the control group (3.02±0.85 mmol/L vs 0.94±0.33 mmol/L,P＜0.01).Psychological stress resulted in quantitative alterations in the aerobes (E. coli). There was an increase in the number of E. coli in the proximal small intestinal flora (1.79±0.27 log10(CFU/g) vs 1.32±0.22 log10(CFU/g),P＜0.01), and there was decrease in relative proportion of Lactobacilli and E. coli of stressed mice (0.52±0.56 vs 1.14±1.07,P＜0.05), while there was no significant difference in the anaerobes(Lactobacilli) between the two groups (2.31±0.63 log10(CFU/g) vs 2.41±0.34 log10(CFU/g) P＞0.05). D-xylose concentrations in plasma was significantly and positively correlated with the number of E. coli in the proximal small intestinal flora (r=0.6713,P＜0.05). Conclusion Small intestinal disfunction under psychological stress may be related to dysbacteriosis and the damage of mucosa.

Objective　To study the clinical features and operative methods for patients with hepatic tuberculosis.Methods　The clinical features、diagnosis、operative methods and the location of tuberculosis focus in the liver were analysed in 8 patients.Results　Difinite preoperative diagnosis could be reached in none of the 8 patients.Surgical procedure included focus remove (5 cases) and deroof plus drainage (3 cases).The diagnosis of hepatic tuberculosis was proved by pathological examination.Conclusions　Surgical resection plus anti-tuberculosis drugs are the mainstay for the treatment of patients with hepatic tuberculosis.

BACKGROUND: The nano-hydroxyapatite (NHA) biomaterials compounded with secondary phase or multiphase materials have been widely used in the domain of stomatology, and there have been several reports regarding the application of compounded NHA with composite resin. OBJECTIVE: To analyze the application progress of NHA in the domain of stomatology, and to prospect the potential significance of NHA in the stomatology materials. METHODS: Databases of Pubmed, EBSCOhost and China Journal Full-text were retrieved to screen out the articles. Inclusion crteria: ①The articles possess originality and dependable point and evidence. ②The articles have conclusive viewpoint and allround analyses. ③The agents of articles contact with this review closely.Exclusion criteria:repetition research and independent literatures with this review. And 24 literatures in accordance with the standard were selected in this study. RESULTS AND CONCLUSION: Many clinical application and animal experiments indicate that NHA has been extensively used in the oral surgery, endodontic, implantation and the other aspects, with the deeply research for combination of NHA and composite resin, NHA hopefully displays greater effectiveness in the stomatology materials.

Since the first description of tension-free herniorrhaphy and the developement of prosthetic ma-terial for inguinal hernia, many techniques have come and gone. We should deploy the idea of evidence-based medicine and clinical practice guideline, according to the pathogenetie condition and medical condi-tion, in order to make the best treatment perseription for patient under the condition of nomudization.

Objective To analyze the effect of pain control with radiotherapy in bone metastases from malig-nancies. Methods A total of 72 lesions in forty-two cases with bone mestastases were received 6my X ray. The con-ventional radiotherapy was performed in 28 lesions in the way of 200cGy/fraction,5 fracties/week,total dose of 3000 ～5000cGy. The hypofractionation radiotherapy was.performed in 44 lesions in the way of 400cGy/fracfion,3 frac-tions/week,total dose of 2400～3600cGy. Results Overal pain relief rate was 90.28%, there were no significant differences between the two groups(P 0.05). The pain relief of hypofractionation radiotherapy was faster than anoth-er. Conclusion Radiotherapy is a very effective way to relieve pain in bone metastases from malignacies.