Through application of bacterial biotherapeutic agents on clinical practice, we determined that Lactobacillus GG strains have high effect in treatment for acute diarrhea without blood, colitis caused by Clostridum difficile, diarrhea related to erythromycin, diarrhea with Rotavirus(+). Enterococcus faecium SF68 strain have also good effect in treatment for non-specific acute diarrhea. Steptococcus hemophilus have good effect in prophylaxis treatment. Saccharomyces boulardii was non-bacterial biotherapeutic agents. Only one type of enzyme has proved effectiveness in vivo and in vitro. Saccharomyces boulardii was considered by WHO as a useful agent in treatment for chronic colitis, recurrent colitis related to Clostridium difficile. Freeze-dried Saccharomyces boulardii has less side effects and easy to use
Diarrhea ; Therapeutics

Background: In traditional medicine, there are some herbal medicines and remedies for the treatment of Helicobacter Pylori (HP) infected chronic gastritis. BTB is a remedy that Betelvine combined with \u201cTa kim hoan\u201d remedy and \u201cBach thuoc Cam thao thang\u201d. These medicines are manufactured by the National Hospital of Traditional Medicine. Objectives: (1) To research the analgesic effects, change of endoscopic and histopathological images, anti-HP effects of BTB in the treatment of the HP-infected chronic gastritis. (2) To investigate unexpected side effects of BTB in clinical practice. Subjects and method: 37 chronic gastritis patients with positive HP (based on clinical, endoscopic and histopathological evidences). This was an opened clinical study, comparing results between pre- and post-treatment. Results: BTB could stop epigastric pain (89.2%). The rate of recovering in endoscopic signs was 75.7%. The histopathological results showed that BTB reduced significantly the inflammation level (73% good results); anti-HP rate was 59.5%. Conclusions: In treatment of HP-infected chronic gastritis, BTB could stop pain up to 89.2%. The inflammation level reduced significantly on endoscopic and histopathological images. BTB did not have any unexpected clinical effects.
Traditional medicine ; gastritis ; Helicobacter pylori

Objective: This study aimed to investigate the impact of hyperandrogenism (HA) on the outcomes of ovulation induction (OI) using gonadotropin and intrauterine insemination (IUI) in patients with polycystic ovary syndrome (PCOS). Methods: This was a retrospective cohort study including 415 patients undergoing OI using gonadotropin and IUI treatment between January 2018 and December 2020 at a single infertility center. Baseline characteristics, clinical and laboratory parameters, and pregnancy outcomes were investigated. Results: Among the study population, there were 105 hyperandrogenic (25.3%) and 310 non-hyperandrogenic patients (74.7%). The live birth rate was lower in the HA group than in the non-HA group, but this difference did not reach statistical significance due to the limited sample size (14.3% vs. 21.0%, relative risk=0.68; 95% CI, 0.41–1.14, p=0.153). No predictive factors for live birth were identified through logistic regression analysis. Conclusion HA did not negatively affect the outcomes of OI using gonadotropin and IUI cycles in Vietnamese women with PCOS. The result may not be applicable elsewhere due to the large variation in the characteristics of women with PCOS across races and populations.

Objective: The purpose of this study was to identify factors associated with twin pregnancy following day 3 double embryo transfer (DET). Methods: This retrospective cohort study incorporated data from 16,972 day 3 DET cycles. The participants were women aged between 18 and 45 years who underwent in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) at My Duc Assisted Reproduction Technique Unit (IVFMD), My Duc Hospital, located in Ho Chi Minh City, Vietnam. Results: Of the 16,972 day 3 DET cycles investigated, 8,812 (51.9%) resulted in pregnancy. Of these, 6,108 cycles led to clinical pregnancy, with 1,543 (25.3% of clinical pregnancies) being twin pregnancies. Factors associated with twin pregnancy included age under 35 years (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.32 to 1.71; p<0.001) and cycles involving the transfer of at least one grade I embryo. Relative to the transfer of two grade III embryos, the risk of twin pregnancy was significantly elevated following the transfer of two grade I embryos (OR, 1.40; 95% CI, 1.16 to 1.69; p<0.001) or a combination of one grade I and one grade II embryo (OR, 1.27; 95% CI, 1.05 to 1.55; p=0.001). Conclusion By analyzing a large number of IVF/ICSI cycles, we identified several predictors of twin pregnancy. These findings can assist medical professionals in tailoring treatment strategies for couples with infertility.