1.Efficacy of Intravitreal Triamcinolone Acetonide for Eyes with Postvitrectomy Diabetic Vitreous Hemorrhage.
Sun Young LEE ; Hee Gyung LEE ; Hyewon CHUNG ; Young Hee YOON ; June Gone KIM
Korean Journal of Ophthalmology 2007;21(4):208-212
PURPOSE: To evaluate the efficacy of intravitreal triamcinolone acetonide (IVT) for the management of postvitrectomy diabetic vitreous hemorrhage. METHODS: The authors conducted a retrospective study of patients with postvitrectomy diabetic vitreous hemorrhage who were administered 4 mg (0.1 cc) of triamcinolone acetonide ophthalmic suspension. Ocular history, adverse events, BCVA, intraocular pressure, external eye examination, slit-lamp biomicroscopy, fundus examination, B-scan ultrasonography, and fundus photography were assessed on day 1, weeks 1, 2, and 4 and months 2 and 3. RESULTS: There were 19 eyes of 18 consecutive patients with mean follow-up after IVT injection of 28 weeks. Of the 19 eyes, 17 eyes (89%) experienced clearing of vitreous hemorrhage within 1 to 5 weeks (mean, 1.7 weeks) with visible triamcinolone precipitates along with blood clot in the inferior aspect of fundus. Of these 17 eyes, 12 eyes (63%) maintained vitreous hemorrhage-free condition at last follow-up with a mean visual acuity of 20/63 (range, 20/320 20/25), whereas 5 (29%) developed recurrent vitreous hemorrhage after clearing of vitreous hemorrhage. Vitreous hemorrhage was not cleared in 2 eyes, which required surgical procedures. CONCLUSIONS: IVT injection may be beneficial for clearing recurrent postvitrectomy Diabetic Vitreous Hemorrhage.
Adult
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Aged
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Diabetic Retinopathy/*complications/diagnosis
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Female
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Follow-Up Studies
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Glucocorticoids/*administration & dosage
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Humans
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Injections
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Male
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Microscopy, Acoustic
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Middle Aged
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Postoperative Hemorrhage/diagnosis/*drug therapy/etiology
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Retrospective Studies
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Time Factors
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Treatment Outcome
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Triamcinolone Acetonide/*administration & dosage
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Visual Acuity
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Vitrectomy/*adverse effects
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Vitreous Body
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Vitreous Hemorrhage/diagnosis/*drug therapy/etiology
2.A Case of Accidental Macular Injury by Nd: YAG Laser and Subsequent 6 Year Follow-Up.
Korean Journal of Ophthalmology 2009;23(3):207-209
Here, we report the case of a patient who sustained Nd: YAG laser macular injury with subsequent 6 year follow-up evaluation. A 23-year-old female was accidentally exposed to a Q-switched Nd: YAG laser without protective goggles. Upon initial evaluation, the best-corrected visual acuity of her affected eye was 20/100 OD. Fundoscopic examination revealed a macular laser burn and vitreous hemorrhage. Corticosteroids, in the form of 60 mg prednisolone, were administered orally with a 10 mg per week taper. Nineteen days following exposure, fundoscopic examination revealed a distinct epiretinal membrane which resolved within six months. The best-corrected visual acuity of the affected eye remained 20/100 OD. This clinical course is similar to those of previously reported cases including vitreous hemorrhage and subsequent epiretinal membrane formation. However, visual acuity did not recover despite spontaneous regression of the epiretinal membrane and at 6 year follow-up, there was neither choroidal neovascularization nor macular hole formation.
Accidents
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Female
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Fluorescein Angiography
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Follow-Up Studies
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Fundus Oculi
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Glucocorticoids/therapeutic use
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Humans
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Lasers, Solid-State/*adverse effects
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Macula Lutea/*injuries
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Prednisolone/therapeutic use
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*Radiation Injuries/complications/diagnosis/drug therapy/physiopathology
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Treatment Outcome
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Visual Acuity/radiation effects
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Vitreous Hemorrhage/etiology/pathology
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Young Adult