No abstract available.
Vitamin K Deficiency* ; Vitamin K* ; Vitamins*

No abstract available.
Vitamin K Deficiency* ; Vitamin K* ; Vitamins*

Background: Intracranial hemorrhage (lCH) is a common disease with high rate of mortality and neurological sequel. Objectives:to estimate preventive effectiveness of intracranial hemorrhage by vitamin K1 and K3 for newborns just after birth". Subjects and methods: An epidemiological, randomized control study with intervention was conducted. The study included all children under 3 months with and without ICH during period 1/1/2000 -30/6/2004 living in Hatay province. Among them all the newborns during period 1/6/2002 - 30/6/2004 were injected either 1 mg vitamin K1 or K3. Results: Children injected with vitamin K in the intervention period were followed up in three months and evaluated by a united process. Effects of intervention were calculated by preventive value. 62.057/82069 newborns were injected vitamin K1 or Vitamin K3 (25.725 newborns were injected Vitamin K1; 36.332 newborns were injected vitamin K3). Single dose 1M reduced the rate of ICH in infants: The morbidity changed from 3.3\ufffd?to 0.82\ufffd? the prevention value was 96%. There were no complications and side effects of vitamin K injections reported. Conclusions: Injection of vitamin K1 and K3 have similar preventive effectiveness. Vitamin K injection 1M with recommended dose was safe for newborns.\r\n', u' \r\n', u'\r\n', u'
Intracranial Hemorrhages ; Vitamin K Deficiency

No abstract available.
Humans ; Infant, Newborn* ; Vitamin K Deficiency* ; Vitamin K* ; Vitamins*

No abstract available.
Diagnosis* ; Intracranial Hemorrhages* ; Vitamin K Deficiency* ; Vitamin K* ; Vitamins*

No abstract available.
Diagnosis* ; Intracranial Hemorrhages* ; Vitamin K Deficiency* ; Vitamin K* ; Vitamins*

A hemorrhagic disease due to prothrombin complex deficiency os described in 4 infants from 1 to 11 months of age. This disease is different from the hemorrhagic disease of the newborn. The main differences are that it is found in an older age group and that intracranial hemorrhages are frequent. Rapid clinical and laboratory response after vitamin K therapy are observed. Severe prothrmbin complex deficiency due to vitamin K deficiency is a accounted for the pathogenesis of bleeding. Possible causes of vitaimn K deficiency are reviewed.
Hemorrhage ; Humans ; Infant ; Infant, Newborn ; Intracranial Hemorrhages ; Prothrombin ; Vitamin K ; Vitamin K Deficiency

Hemorrhage ; etiology ; physiopathology ; Humans ; Time Factors ; Vitamin K Deficiency ; complications

Binder syndrome is a maxillonasal dysostosis characterized by midface and nasal hypoplasia. It is sometimes associated with short terminal phalanges of fingers and toes and transient radiological features of chondrodysplasia punctata. It is associated with vitamin K deficiency during pregnancy. We describe here a baby with Binder syndrome who was born from mother with cholelithiasis during pregnancy.
Cholelithiasis ; Chondrodysplasia Punctata ; Dysostoses ; Finger Phalanges ; Humans ; Infant ; Maxilla ; Maxillofacial Abnormalities ; Mothers ; Nose ; Pregnancy ; Toes ; Vitamin K ; Vitamin K Deficiency

A 4-week-old infant presented with a coagulation disorder resulting from a vitamin K deficiency. The vitamin K deficiency was caused by neonatal cholestasis due to biliary atresia. Jaundice, hepatomegaly and pale stools are the predominant presenting symptoms of biliary atresia, none of which were recognized in our patient before admission. However, the patient presented with bleeding caused by vitamin K deficiency. She was fully breastfed and had received adequate doses of vitamin K at birth and from the age of 1 week. In case of a hemorrhagic diathesis due to neonatal cholestasis, timely identification of treatable underlying disorders, in particular biliary atresia, is important because an early surgical intervention results in a better prognosis. Meticulous history taking and a thorough physical exam can be decisive for an early diagnosis and subsequent intervention.
Biliary Atresia ; Cholestasis* ; Early Diagnosis ; Hemorrhage ; Hemorrhagic Disorders* ; Hepatomegaly ; Humans ; Infant ; Jaundice ; Parturition ; Prognosis ; Vitamin K ; Vitamin K Deficiency