Benign paroxysmal positional vertigo（BPPV）is a common peripheral vestibular disorder，and at present，otolith shedding and displacement is highly recognized as the main pathological mechanism of BPPV. An increasing amount of evidence has shown that otolith particle shedding is closely associated with vitamin D，and 25-（OH）D is expected to become a potential biomarker for BPPV and an important target for the treatment of BPPV and residual symptoms after successful repositioning. This article reviews the pathophysiological mechanism of vitamin D in BPPV and residual dizziness and summarizes the association of vitamin D with BPPV and residual symptoms based on the treatment methods for vitamin D regulation.
Vitamin D

Humans ; Vitamin D ; Vitamin D Deficiency

Humans ; Vitamin D ; Vitamin D Deficiency

Objectives: This study aimed to compare the severity of COVID-19, inflammatory parameters and clinical outcomes among patients with normal and subnormal levels of Vitamin D. Methodology: This is a retrospective cohort study of 135 patients admitted in a tertiary hospital for COVID-19. Patients were grouped according to their Vitamin D level. Primary outcome measure was the composite of all-cause mortality and morbidity. Other outcome measures determined were the comparison among the groups on the severity of COVID-19 infection, changes in inflammatory parameters, length of hospital stay and duration of respiratory support. Results: There was a significant trend of higher ICU admission (p=0.024), mortality (p=0.006) and poor clinical outcome (p=0.009) among the Vitamin D deficient group. No significant difference was found for most of the inflammatory parameters, duration of hospital stay and respiratory support. Overall, patients with deficient, but not insufficient Vitamin D level had 6 times higher odds of composite poor outcome than those with normal Vitamin D (crude OR=5.18, p=0.003; adjusted OR=6.3, p=0.043). Conclusion The inverse relationship between Vitamin D level and poor composite outcome observed in our study suggests that low Vitamin D may be a risk factor for poor prognosis among patients admitted for COVID-19.
Vitamin D ; Vitamin D Deficiency ; COVID-19

No abstract available.
Vitamin D* ; Vitamins*

No abstract available.
Vitamin D ; Vitamins

The study built process of extraction vitamin D3 in Patarvit syrup by SPE technique with mean extract performance as 98.2%. Chromatography was built to quantity vitamin D3 as following: Lichrosorb RP 18 column (250 X 4 mm, 5 and 10µm ); Detector UV: 265 nm; movement phase: Methanol-ethyl acetate - water (90:7:3); stream speed: 1.5ml/minute. Injection volume: 20µl. The method had a high accuracy (E% = 1.18%). Percentage of withdrawal was 96.8% with E% = 0.71%; the limit of detection (LOD) was 5.79IU/ml, the limit of quantitative (LOQ) was 19.3IU/ml
Vitamin D ; Pharmaceutical Preparations

No abstract available.
Vitamin D* ; Vitamins*

No abstract available.
Vitamin D ; Vitamins

No abstract available.
Vitamin D ; Vitamins