A meta-analyze on vitamin A (VA) and anemia surveys in the year 1995 and 2000. The results showed that anemis is reducing during the recent years, particularly more in pregnancy women, and less in young infants. However anemis is still a public health significant problem (PHS). Clinical VA lesions are continuously lower than PHS. While the sub-clinical VA deficiency is still a PHS, of which majority is in mild and moderate levels. It was recognized that the problem is more severe in young infant < 6 months. Low VA content in breast-milk is more than 50% among lactating women. The recommendations, such as social marketing on the using iron tablet, iron fortification into several foods have been developed for control of anemia; VA capsule supplementation of 50,000 IU to the infant < 6 months combined with immunization of PDT on 6, 10, 14 weeks; Increasing doses of VA for women after delivery. Weekly supplementation of iron combined with low dose VA to pregnance women
Vitamin A ; Anemia ; Vitamin A Deficiency

The research was conducted on 260 mothers from 22 to 32 years old to study knowledge, attitude and practice in prevention vitamin A deficiency at 2 communes of My Loc district, Nam Dinh province. 83,8% of the mothers understood that using vitamin A rich foods could protect against vitamin A deficiency and 47,3% of them knew about role of high dose of vitamin A capsule approach, 82,7% mothers thought that vitamin A campaign is very necessary for children. There were only 12.5% mothers used vegetables and 33,6% used cooking oil/fat regularly for their children’s meals because the majority of them thought these foods were difficult to digest in their children. The number of mothers usually prepare supplementary foods for their children with 4 food groups only was 9,1%. The number of mothers did not give their children animal food; cooking oi/fat when they suffered from measles, diarrhea and ARI was 14,3%, 28,6% and 22.5%, respectively.
Vitamin A Deficiency ; Child ; Mothers

A iron sectional study was carried out on 323 children aged 5-8 months old in Dong Hy district, Thai Nguyen province from August 2002 to October 2003. Results showed: malnutrition of underweight accounted for 3.1%, underheight 11.5%, neonatal weight < 2.500g was 8.4%, anemia 74.6% and vitamin A deficiency 39.3%. There is a closed and positive relation between anemia and vitamin A deficiency, children with anemia had a risk of vitamin A deficiency 2, 3 times higher than normal children and controversaly. Knowledge and practice of mothers on breast feeding, on children care and on supplemented foods have had large shortcomings
Anemia ; vitamin A deficiency ; Malnutrition

Vitamin D has been the focus of much scientific literature in recent years owing to various studies showing its association with a wide variety of pathological conditions 1,2 . Sun exposure, diet and fortified supplementation account for a bulk of Vitamin D intake in humans. Activation of vitamin D is sequential and requires sun exposure for conversion of 7- dehydrocholesterol to Vitamin D3. Further metabolism in the liver converts Vitamin D3 to 25 –hydroxyvitamin D3. Conversion to its active form 1,25 dihydroxyvitamin D3 (Calcitriol) occurs in the kidneys 2 . The importance of Vitamin D in calcium metabolism and bone health is well known and documented. Controversies exist regarding the true prevalence of hypovitaminosis, however in developing countries the prevalence of vitamin D deficiency in all age groups is probably higher 3 . Adding to this the burden and morbidity of skeletal trauma, persistent deficiency may have a deleterious effect in the injured 4, 5 . Vitamin D, with its positive effect on bone health does play a role in the biology of fracture repair and remodelling 6 . The role of Vitamin D replacement as sole biological effectors in fracture repair may be difficult to quantify and confounded by other variables at play in bone healing. Studies looking at vitamin D levels in orthopaedic patients have also shown significant levels of deficiency and have put forward recommendations for evaluation and supplementation
Vitamin D Deficiency

Introduction: Derangement in calcium homeostasis is common in nephrotic syndrome (NS). It is postulated that low serum total calcium and vitamin D levels are due to loss of protein-bound calcium and vitamin D. It is unclear if free calcium and free vitamin D levels are truly low. The guideline is lacking with regards to calcium and vitamin D supplementation in NS. This study aims to examine calcium and vitamin D homeostasis and bone turnover in NS to guide practice in calcium and vitamin D levels supplementation. Methodology: This is a prospective pilot study of ten patients diagnosed with NS, and eight healthy controls. Calcium, vitamin D, and bone turnover-related analytes were assessed at baseline, partial and complete remission in NS patients and in healthy controls. Results: NS patients had low free and total serum calcium, low total 25(OH)D, normal total 1,25(OH)D levels and lack of parathyroid hormone response. With remission of disease, serum calcium and vitamin D metabolites improved. However, nephrotic patients who do not attain complete disease remission continue to have low 25(OH)D level. Conclusion In this study, the vitamin D and calcium derangement observed at nephrotic syndrome presentation trended towards normalisation in remission. This suggested calcium and vitamin D replacement may not be indicated in early-phase nephrotic syndrome but may be considered in prolonged nephrotic syndrome.
Vitamin D Deficiency

Background: Apart from its role in bone health, recent developments have shown that vitamin D also has anti-inflammatory properties, and therefore may have a role in inflammatory bowel disease (IBD) in children. Objectives: To determine the effect of vitamin D supplementation on the disease activity of pediatric patients with IBD. Design: Random-effects meta-analysis Data Sources: : Studies were searched at Cochrane Library, PubMed, EBSCO Host, ScienceDirect, Google Scholar, and Wiley Online. Review Methods: Experimental studies measuring the effect of vitamin D on the disease activity of pediatric patients with IBD were included. The proportion of disease activity, measured as remission rate or inactivity using Pediatric Crohn’s Disease Activity Index (PCDAI) or Pediatric Ulcerative Colitis Activity Index (PUCAI), and the mean and standard deviation of mean serum vitamin D [25(OH)D] level, change in 25(OH)D, and different inflammatory markers [erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP)] were extracted or estimated and recorded in an abstraction form. Standardized mean difference and odds ratio were used as summary effect measures and estimated using Stata/Multiprocessor. Results: The serum 25(OH)D (SMD = 1.75, z = 2.33, p = 0.001) and change in 25(OH)D (SMD = 3.37, z = 2.34, p = 0.019) was significantly higher among those who received a high dose of vitamin D. However, a significantly high heterogeneity was estimated (I2 >50%). For the disease activity of IBD, the standard mean difference of mean ESR (SMD = –1.10, z = 5.35, p = 0.001) was significantly lower with high-dose vitamin D. The likelihood of remission rate using the Pediatric Crohn’s Disease Activity Index (PCDAI) or Pediatric Ulcerative Colitis Activity Index (PUCAI), and standardized mean difference of CRP were not significantly different among those who received high-dose and low-dose vitamin D. Conclusion Cognizant of the functions of vitamin D in enhancing intestinal flora balance, regulating immunologic response, and improving intestinal mucosal barrier, vitamin D can be recommended as a supplementary treatment for IBD among the pediatric population. Nevertheless, there is still insufficient evidence for the cut-off level of adequate levels of serum 25(OH)D among pediatric patients with IBD, thus necessitating further studies.
Vitamin D Deficiency

No abstract available.
Vitamin K Deficiency* ; Vitamin K* ; Vitamins*

No abstract available.
Vitamin K Deficiency* ; Vitamin K* ; Vitamins*

Vitamin A is an important micronutrient for human health. It has a good effect on many diseases such as diarrhea, malnutrition, HIV/AIDS, malaria... Vitamin A and/or -carotene as well as other micronutrients contribute to many physiological and pathological process of the body. In Vietnam, the rate of Vitamin A deficiency remains high. Therefore, it should have a strategy for mass complement of vitamin A, high dose and periodical complement of vitamin A for children, vitamin A containing diets and health education.
vitamin A ; Solutions ; Vitamin A Deficiency ; prevention & control

Vitamin A (VA) status was assessed in young children and lactating women in Red River Delta area. Results showed that pre-clinical VA deficiency rate, expressed by low level of retinol in serum and in milk is very frequent (10.8% in children, and 56.3% in lactating women) and was at, severity degree according to the IVACG/WHO classification. Low levels of VA and lipid in the dietary intake are a major cause of VA deficiency in the rural community in Vietnam
Vitamin A ; child ; Vitamin A Deficiency ; risk factors ; women