1.Associations of Sarcopenia, Handgrip Strength and Calf Circumference with Cognitive Impairment among Chinese Older Adults.
Bing WU ; Yue Bin LYU ; Zhao Jin CAO ; Yuan WEI ; Wan Ying SHI ; Xiang GAO ; Jin Hui ZHOU ; Virginia Byers KRAUS ; Feng ZHAO ; Xin CHEN ; Feng LU ; Ming Yuan ZHANG ; Ying Chun LIU ; Qi Yue TAN ; Shi Xun SONG ; Ying Li QU ; Xu Lin ZHENG ; Chong SHEN ; Chen MAO ; Xiao Ming SHI
Biomedical and Environmental Sciences 2021;34(11):859-870
Objective:
To evaluate the associations of sarcopenia, handgrip strength and calf circumference with cognitive impairment among Chinese older adults.
Methods:
Totally 2,525 older adults were recruited from the Healthy Aging and Biomarkers Cohort Study. Cognitive impairment was assessed by the Chinese Mini-Mental State Examination. Handgrip strength was calculated from the means of the right and left hand values. Calf circumference was measured at the site of maximum circumference of the non-dominant leg. The formula developed by Ishii was used to define sarcopenia. Multiple logistic regression was performed to evaluate the associations of sarcopenia, handgrip strength, and calf circumference with cognitive impairment.
Results:
The prevalence of cognitive impairment was 34.36%. The adjusted odds ratio (
Conclusion
Sarcopenia, identified by low handgrip strength and low calf circumference, was positively associated with cognitive impairment.
Aged
;
Aged, 80 and over
;
China/epidemiology*
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Cognitive Dysfunction/etiology*
;
Female
;
Hand Strength
;
Humans
;
Leg/anatomy & histology*
;
Logistic Models
;
Male
;
Sarcopenia/pathology*
Result Analysis
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