1.Studying the changes of leukocyte, erythrocyte and bone-marrow of mice treated by gamma irradiation
Journal of Vietnamese Medicine 2005;0(2):22-25
Studying the effectiveness of irradiation on bone-marrow, the numbers of leukocyte, erythrocyte, hemoglobin of mice (25 normal mice and 35 mice treated by gamma irradiation with the dose of 600 rad/(100rad/day) (60 Co) showed that: Gamma irradiation reduced total of leucocytes, the number of different leucocytic (lymphocyte, granulocyte, mono and natural killer cells), the ratio of reticulocyte, number of mature erythrocyte and hemoglobin: Total of leucocytes (3,14 ± 1,58 in comparison with 13,45 ± 4,6); monocytes (0,05 ± 0,03 in comparison with 0,26 ± 0,13), lymphocytes (1,66 ± 0,36 in comparison with 6,34 ± 2,84). After gamma irradiation, the number of reticulocyte was 55%, mature erythrocyte was 73% and hemoglobin was 82%
Therapeutics
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Mice
2.Immunosuppressed model for experimental mice by cyclophosphamid
Journal of Vietnamese Medicine 2004;296(3):57-60
Study on white mices with age of 6-8 weeks, 18-20g body weight. They were divided into 3 groups: group 1 (control group): 30 mices; group 2: mices were immunesuppressed by 200mg cyclophosphamid per one kilogram of body weight, being checked after 5 days of injection; and 300mg cyclophosphamid per one kilogram (200mg on the first day and 100mg on the fifth day) and it was checked after 10 days of injection (group 3). The results: immunesuppressed model implemented by intraperitonial injection of 200mg per one kilogram of body weight checked after 5 days of injeciton. These parameters were used to assign the immune function
Immunosuppressive Agents
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Mice
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Animal Experimentation
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Cyclophosphamide
3.The effects of "DYI" on experimental Heterogenous skin graft and mixed lymphocytic culture of human
Journal of Vietnamese Medicine 2004;300(7):27-29
Heterogenous transplantation of skin was studied on two strains of mice BALB/C and Swiss.The subjects were divided into various groups :normal group, cyclophosphamid (CP) inhibited group, cyclosporin A (CPA) inhibited group, and the group processed with DY1. The onset of reject phenomenon of the graft and the completed reject of the graft in the groups of mice using CP, CPA and DY1 were more delayed in comparing with the controlled subjects. The cell numbers decreased and the percentage of transformed cells also decreased in all groups using CP, CPA and DY1
Skin Transplantation
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Mice
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Cells
4.Histopathology of minor salivary gland biopsies in Gougerot-Sj\xf6gren syndrome combined to rheumatoid arthritis
Journal of Medical Research 2007;53(5):134-138
Background: The minor salivary gland biopsy is an important diagnostic criterion of Gougerot-Sj\xf6gren syndrome. Objective: To describe histopathological characteristics of minor salivary gland of Gougerot-Sj\xf6gren syndrome combined to rheumatoid arthritis. Subjects and method: A prospective, descriptive, cross-sectional study included 108 patients with rheumatoid arthritis, who treated at Department of Rheumatology of Bach Mai hospital, from 1998 to 2003. The patients were divided into 2 groups: 50 patients with Gougerot-Sj\xf6gren syndrome and 58 patients without Gougerot-Sj\xf6gren syndrome. Results: Characteristics of minor salivary gland biopsy were lymphocytic infiltration of minor salivary glands (96%) with various distribution: periductal (86%), periacinic (72%), perivascular (36%). 78% of cases were plasmocytic infiltration, with periductal distribution (70%). 82% of cases were 3, 4 stages according to Chilsom clsssification. 67.5% of cases had ductal abnormality, glandular atrophy (62%), vascular edema (58%). Conclusion: Incidence of 3, 4 stages according to Chilsom classification was 82% in rheumatoid arthritis patients with Gougerot-Sj\xf6gren syndrome.
Arthritis
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Rheumatoid/ pathology
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diagnosis
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Sjogren's Syndrome/ pathology
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diagnosis
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Salivary Glands
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Minor/ pathology
5.Efficacy and tolerance of GINKOR FORT in the treatment of quite
Journal of Vietnamese Medicine 2001;256(2):46-53
109 patients (male: 60) with ages of 18-80 suffering the previous untreated acute haemorrhoid (congestive symptoms, no complication) administrated Ginkor fort at dose of 2 tablets x 3 times within the first 2 days and 2 tablets x 2 times a day within following 4 days. The results have shown that Ginkor fort had a rapid analgesic effect (55% of patient with pain free). The drug improved obviously the bleeding, even no bleeding (87.1%). 78.9% of patients had no pain at the sixth day. 94.5% of patients had obvious pain relief or bleeding reduction. There was a difference of these between the second day and sixth day. The itching, desire for movement and leakage improved among 80% of patient in the sixth day. The rate of good tolerance of Ginkor fort was 97.2%.
Ginkor fort
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Therapeutics
6.Ambulatory haemorrhoidectomy by laser CO2.
Journal of Preventive Medicine 2001;11(4):25-33
A prospective study of ambulatory CO2 laser hemorrhoidectomy. 295 consecutive patients (147 males, 148 females), mean age of 39 years (18-72), 97 cases of them (41 circumferential hemorrhoids, 56 piles) were strict follow-up from 3 months to one year. All had been operated by “restricted and pile-size hemorrhoidectomy” technique and performed with CO2¬ laser. Less operative bleeding (about 90% <20 ml), operating faster (average: 23.58 min), less painful (78.4% degree A + B), none post - op, hemorrhage, mean wound healing within 4 weeks, none late complication (anal fissure, fistula, deformity...) and recurrence. Hemorrhoidectomy using CO2 laser and author’s technique is safe, effective and no-hospitalization.
Hemorrhoids
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surgery
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therapeutics
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lasers
7.Circumferential haemorrhoidectomy by laser CO2
Journal of Vietnamese Medicine 1999;233(2):37-45
Purpose: Estimate the results of circumferential haemorrhoidectomy with laser CO2. Methods: A prospective study of 228 patients with circumferential haemorrhoids. All had been operated by "restricted and pilesize heamorrhoidectomy" technique and performed with laser CO2. Follow up 1 year to over 5 years. Results: less operative bleeding, operating faster, less post-op, painful and heamorrhage, mean wound healing within 24 days, short hospitalization, none late complication (anal fissura, fistula, whitehead deformity...) and recurrence. Conclusion: Circumferential heamorrhoidectomy using laser CO2 and author's technique is safe, effective and quick recover.
Surgery
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Hemorrhoids
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lasers
8.The accuracy of urease-test conducted with the reagents prepared in Friendship Hospital in the diagnosis of Helicobacter pylori
Journal of Medical and Pharmaceutical Information 2001;(11):34-37
Using the reagents produced in Friendship Hospital, urease-test was carried out with the sensitivity of 92.9%, specificity of 95.5%, and validity of positive prognosis 96.0%, of negative prognosis of 94%. The test gives promptly reliable results
Urease
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Helicobacter pylori
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Indicators and Reagents
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diagnosis
9.The prevalence of Helicobacter pylori infection in Vietnam and in Australia
Journal of Medical and Pharmaceutical Information 2001;8():23-29
Study on 732 Australia dyspeptic patients with infection of H. pylori, in which there are 96 Vietnamese immigrants. Results: Among dyspeptic patients, the prevalence of H. pylori infection in Vietnam (63.7%, 95%Cl: 62.7-64.7%) was statistically higher than that in Australia (46.4%, 95%Cl: 46.0-46.8%). The spectrum of GD diseases in Vietnamese dyspeptic patients is very different from that of Australian patients with higher DU and GU and lower GORD and Barrett's epithelium. The prevalence of H. pylori infection in Vietnamese patients in Hanoi is not different from that of Vietnamese immigrants in Australia. In contrast, GoRD is found about 7 times more frequent in Vietnamese immigrants compared with Vietnamese patients living in Hanoi.
Stomach Diseases
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Helicobacter pylori
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Infection
10.An investigation of dust in some facilities of stone exploitation in Binh Dinh province
Journal of Practical Medicine 2002;435(11):51-52
A cross sectional study on the stone dust in the working environment in mines of AC, 504 in Binh Dinh province in dry seasons during 1998 and 1999, has shown that the dust contamination level was high. All indicators were above allowed standards. 9/14 of samples had an airway dust level higher 1-9 time than this of allowed standards. 100% of samples had the total dust level higher 4-37 times than this of allowed standards. The silicon levels in the stone mine of Phu Ly (4-5%) and Hoa An (22-23%). This is cause of silicosis among workers of these facilities.
Dust
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Therapies, Investigational