1.Changes in erythrocyte, leucocyte and platelet in people having frequent contact with chemicals
Journal of Vietnamese Medicine 2004;295(2):23-26
In this study, 48 long-term exposed people with polychemicals (the male/female ratio is 1/3, the age from 23 to 44): such as organic and iso-organic acids: benzene, toluene and their coequals were investigated. 17 normal people not exposed with polychemicals as the control group. Results were shown following: quantity of erythrocyte was lower than control group but not significantly. Leucocytes especially neutrophils reduced significantly (p<0.001). 15/48 cases (30%) appereared lymphoblast. There is no difference in platelet between studied group and control group
Chemistry
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Diagnosis
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Erythrocytes
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Blood Platelets
2.Contribute to understand the effect of chemicals on immunological responding capacity of people having frequent and long contact
Journal of Vietnamese Medicine 2004;295(2):40-42
Study on 48 people, of whom 16 are male and 32 are female, from 23 to 44 years old. They were long exposed with poly-chemicals, such as organic and iso-organic acids: benzene, toluene and their coequals. The parameters have been used: phagocyte capablity and phagocyte index of neutrophils; E, rossett formed T cells. The results showed that: Phagocyte capability and phagocyte index of neutrophils decreased significantly comparing with control group (p<0.001)
Chemistry
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Allergy and Immunology
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Epidemiology
3.Circulating immune-complexes in acute leprosy, chronic hepatitis, pharynx cancer and acute myelogenous leukemia
Journal of Vietnamese Medicine 2004;295(2):49-52
20 patients with acute leprosy, 12 patients with chronic hepatitis, 34 patients with acute myelogenous leukemia, 48 patients with pharynx cancer. 31 normal healthy persons in the control group. Immune-complexes were fixed quantity by 2 methods: precipitating the immune-complexes with PEG having molecular weight 6.10¬3 and better method. Immune-complexes (+) were identified on acute leprosy, chronic hepatitis and acute diseases with the ratio of positive differences depending on disease, stage and the character of applying technique
Leprosy
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Hepatitis, Chronic
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Pharyngeal Neoplasms
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Leukemia, Myeloid, Acute
4.Ratio of B virus infection in Muong minority pupils
Journal of Vietnamese Medicine 2004;295(2):53-55
115/400 Muong minority pupils of boarding school in Hoa Binh province, all studied subjects have 3 genarations of Muong minority (grandparents, parents and themshelves being Muong minority), from 15 to 19 years old. Using Sero check product of USA to examine the ratio of HBsAg. Results: 19.05% of the boys having HBsAg(+), 13.38% of the girls having HBsAg(+). So the ratio of HBsAg(+) in girls are lower than in boys but it is not significant. The ratio of HBsAg(+) at the age of 15 is 19.61%, the age of 16-17 is 14.74% and the age of 18-19 is 16.67%, there is not significant between groups
Hepatitis B virus
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Epidemiology
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Pupil
5.To evaluate the influence of clarithromycin, metronidazple resistance on the efficacy of 3 procedures of OAC, OMC, OAM during 7 days for treating gastroduodenal ulcer with positive Helicobacter pylori
Journal of Practical Medicine 2003;454(6):58-61
clarithromycin, metronidazple, OAC, OMC, OAM, Helicobacter pylori, gastroduodenal
215 patients with gastroduodenal ulcer were divided into 3 groups for treating with the precedures of OAM, OAC, and OMC. Results showed that the OAM gave lowest efficacy because of high resistance to metronidazole in community. OAC gave the most efficacy though it was affected evidently by clarithromycine resistance. OMC was affected lightly by metronidazole resistance. The results of treatment was satisfied relatively because of the combined effect of clarythromycine. In case of an allergy with penicillin, this is the procedure of choice
Helicobacter pylori
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Peptic Ulcer
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Diseases
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Therapeutics
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drugs
6.Studying the changes of leukocyte, erythrocyte and bone-marrow of mice treated by gamma irradiation
Journal of Vietnamese Medicine 2005;0(2):22-25
Studying the effectiveness of irradiation on bone-marrow, the numbers of leukocyte, erythrocyte, hemoglobin of mice (25 normal mice and 35 mice treated by gamma irradiation with the dose of 600 rad/(100rad/day) (60 Co) showed that: Gamma irradiation reduced total of leucocytes, the number of different leucocytic (lymphocyte, granulocyte, mono and natural killer cells), the ratio of reticulocyte, number of mature erythrocyte and hemoglobin: Total of leucocytes (3,14 ± 1,58 in comparison with 13,45 ± 4,6); monocytes (0,05 ± 0,03 in comparison with 0,26 ± 0,13), lymphocytes (1,66 ± 0,36 in comparison with 6,34 ± 2,84). After gamma irradiation, the number of reticulocyte was 55%, mature erythrocyte was 73% and hemoglobin was 82%
Therapeutics
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Mice
7.Immunosuppressed model for experimental mice by cyclophosphamid
Journal of Vietnamese Medicine 2004;296(3):57-60
Study on white mices with age of 6-8 weeks, 18-20g body weight. They were divided into 3 groups: group 1 (control group): 30 mices; group 2: mices were immunesuppressed by 200mg cyclophosphamid per one kilogram of body weight, being checked after 5 days of injection; and 300mg cyclophosphamid per one kilogram (200mg on the first day and 100mg on the fifth day) and it was checked after 10 days of injection (group 3). The results: immunesuppressed model implemented by intraperitonial injection of 200mg per one kilogram of body weight checked after 5 days of injeciton. These parameters were used to assign the immune function
Immunosuppressive Agents
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Mice
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Animal Experimentation
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Cyclophosphamide
8.The effects of "DYI" on experimental Heterogenous skin graft and mixed lymphocytic culture of human
Journal of Vietnamese Medicine 2004;300(7):27-29
Heterogenous transplantation of skin was studied on two strains of mice BALB/C and Swiss.The subjects were divided into various groups :normal group, cyclophosphamid (CP) inhibited group, cyclosporin A (CPA) inhibited group, and the group processed with DY1. The onset of reject phenomenon of the graft and the completed reject of the graft in the groups of mice using CP, CPA and DY1 were more delayed in comparing with the controlled subjects. The cell numbers decreased and the percentage of transformed cells also decreased in all groups using CP, CPA and DY1
Skin Transplantation
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Mice
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Cells
9.Histopathology of minor salivary gland biopsies in Gougerot-Sj\xf6gren syndrome combined to rheumatoid arthritis
Journal of Medical Research 2007;53(5):134-138
Background: The minor salivary gland biopsy is an important diagnostic criterion of Gougerot-Sj\xf6gren syndrome. Objective: To describe histopathological characteristics of minor salivary gland of Gougerot-Sj\xf6gren syndrome combined to rheumatoid arthritis. Subjects and method: A prospective, descriptive, cross-sectional study included 108 patients with rheumatoid arthritis, who treated at Department of Rheumatology of Bach Mai hospital, from 1998 to 2003. The patients were divided into 2 groups: 50 patients with Gougerot-Sj\xf6gren syndrome and 58 patients without Gougerot-Sj\xf6gren syndrome. Results: Characteristics of minor salivary gland biopsy were lymphocytic infiltration of minor salivary glands (96%) with various distribution: periductal (86%), periacinic (72%), perivascular (36%). 78% of cases were plasmocytic infiltration, with periductal distribution (70%). 82% of cases were 3, 4 stages according to Chilsom clsssification. 67.5% of cases had ductal abnormality, glandular atrophy (62%), vascular edema (58%). Conclusion: Incidence of 3, 4 stages according to Chilsom classification was 82% in rheumatoid arthritis patients with Gougerot-Sj\xf6gren syndrome.
Arthritis
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Rheumatoid/ pathology
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diagnosis
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Sjogren's Syndrome/ pathology
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diagnosis
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Salivary Glands
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Minor/ pathology
10.The accuracy of urease-test conducted with the reagents prepared in Friendship Hospital in the diagnosis of Helicobacter pylori
Journal of Medical and Pharmaceutical Information 2001;(11):34-37
Using the reagents produced in Friendship Hospital, urease-test was carried out with the sensitivity of 92.9%, specificity of 95.5%, and validity of positive prognosis 96.0%, of negative prognosis of 94%. The test gives promptly reliable results
Urease
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Helicobacter pylori
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Indicators and Reagents
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diagnosis