109 patients (male: 60) with ages of 18-80 suffering the previous untreated acute haemorrhoid (congestive symptoms, no complication) administrated Ginkor fort at dose of 2 tablets x 3 times within the first 2 days and 2 tablets x 2 times a day within following 4 days. The results have shown that Ginkor fort had a rapid analgesic effect (55% of patient with pain free). The drug improved obviously the bleeding, even no bleeding (87.1%). 78.9% of patients had no pain at the sixth day. 94.5% of patients had obvious pain relief or bleeding reduction. There was a difference of these between the second day and sixth day. The itching, desire for movement and leakage improved among 80% of patient in the sixth day. The rate of good tolerance of Ginkor fort was 97.2%.
Ginkor fort ; Therapeutics

Studying the effectiveness of irradiation on bone-marrow, the numbers of leukocyte, erythrocyte, hemoglobin of mice (25 normal mice and 35 mice treated by gamma irradiation with the dose of 600 rad/(100rad/day) (60 Co) showed that: Gamma irradiation reduced total of leucocytes, the number of different leucocytic (lymphocyte, granulocyte, mono and natural killer cells), the ratio of reticulocyte, number of mature erythrocyte and hemoglobin: Total of leucocytes (3,14 ± 1,58 in comparison with 13,45 ± 4,6); monocytes (0,05 ± 0,03 in comparison with 0,26 ± 0,13), lymphocytes (1,66 ± 0,36 in comparison with 6,34 ± 2,84). After gamma irradiation, the number of reticulocyte was 55%, mature erythrocyte was 73% and hemoglobin was 82%
Therapeutics ; Mice

Study on white mices with age of 6-8 weeks, 18-20g body weight. They were divided into 3 groups: group 1 (control group): 30 mices; group 2: mices were immunesuppressed by 200mg cyclophosphamid per one kilogram of body weight, being checked after 5 days of injection; and 300mg cyclophosphamid per one kilogram (200mg on the first day and 100mg on the fifth day) and it was checked after 10 days of injection (group 3). The results: immunesuppressed model implemented by intraperitonial injection of 200mg per one kilogram of body weight checked after 5 days of injeciton. These parameters were used to assign the immune function
Immunosuppressive Agents ; Mice ; Animal Experimentation ; Cyclophosphamide

Heterogenous transplantation of skin was studied on two strains of mice BALB/C and Swiss.The subjects were divided into various groups :normal group, cyclophosphamid (CP) inhibited group, cyclosporin A (CPA) inhibited group, and the group processed with DY1. The onset of reject phenomenon of the graft and the completed reject of the graft in the groups of mice using CP, CPA and DY1 were more delayed in comparing with the controlled subjects. The cell numbers decreased and the percentage of transformed cells also decreased in all groups using CP, CPA and DY1
Skin Transplantation ; Mice ; Cells

Use of antibiotic in animal breeding aims to prevention of infection. Especially, the antibiotics is considered as growth stimulation. Although antibiotic mixed with low content, the long- term use of antibiotics leads to more antibiotics resistant microbials than full dosage of it in the short-term. The antibiotic resistant microbials will be pathological factors for human and they transmitted along with foods processing affecting seriously the human health.
Anti-Bacterial Agents ; breeding

Multiple tests are available to diagnose Helicobacter pylori. The aim of this study was to evaluate and compare the sensitivity, specificity and negative and positive predictive values of 13C-Urea breath test (13C-UBT) and other biopsy-based methods in H. pylori diagnosis. A total of 702 patients (mean age, 51.2+/-16.0 years; 327 males and 375 females) were tested for H. pylori infection using 13C-UBT, CLO tests (Delta West, Australia), histology (H&E and modified Giemsa stains), and culture. All patients were untreated for H. pylori infection. Infection status was established by Gold Standard (or culture positive of 2 out of 3 other tests positive). Results suggested that 13C-UBT was the most accurate method for H. pylori diagnosis, although CLO test and histology also produced excellent sensitivity and specificity. Culture method had the best specificity; however, it produced the lowest sensitivity. Combination of histology and CO test gave higher sensitivity and specificity than each method used individually. Conclusion: The noninvasive 13C-BUT is excellent accurate method for determining H. pylori infection when endoscopy is not required. Histology, CLO test and culture are also good methods for H. pylori diagnosis.
Helicobacter pylori ; diagnosis

Using the reagents produced in Friendship Hospital, urease-test was carried out with the sensitivity of 92.9%, specificity of 95.5%, and validity of positive prognosis 96.0%, of negative prognosis of 94%. The test gives promptly reliable results
Urease ; Helicobacter pylori ; Indicators and Reagents ; diagnosis

Study on 732 Australia dyspeptic patients with infection of H. pylori, in which there are 96 Vietnamese immigrants. Results: Among dyspeptic patients, the prevalence of H. pylori infection in Vietnam (63.7%, 95%Cl: 62.7-64.7%) was statistically higher than that in Australia (46.4%, 95%Cl: 46.0-46.8%). The spectrum of GD diseases in Vietnamese dyspeptic patients is very different from that of Australian patients with higher DU and GU and lower GORD and Barrett's epithelium. The prevalence of H. pylori infection in Vietnamese patients in Hanoi is not different from that of Vietnamese immigrants in Australia. In contrast, GoRD is found about 7 times more frequent in Vietnamese immigrants compared with Vietnamese patients living in Hanoi.
Stomach Diseases ; Helicobacter pylori ; Infection

A cross sectional study on the stone dust in the working environment in mines of AC, 504 in Binh Dinh province in dry seasons during 1998 and 1999, has shown that the dust contamination level was high. All indicators were above allowed standards. 9/14 of samples had an airway dust level higher 1-9 time than this of allowed standards. 100% of samples had the total dust level higher 4-37 times than this of allowed standards. The silicon levels in the stone mine of Phu Ly (4-5%) and Hoa An (22-23%). This is cause of silicosis among workers of these facilities.
Dust ; Therapies, Investigational

4(3H)-quinazolinone derivatives were synthesized by the condensation of N-acetylanthranilic acid with aromatic amines or heteroaromatic amines, respectively. The obtained compounds were characterized by their melting point, elemental analysis and the mass, ultraviolet, infrared, 1H and 13C NMR spectra. The obtained derivatives of 4(3H)-quinazolinone were also biologically screened such as: hypnotic, analgesic, antibacterial and cytotoxic activity. 3-(2-hydroxy-3-pyridinyl)-2-methyl-4(3H)-quinazolinon (6) showed potential analgesic activity. No compounds showed hypnotic, cytotoxic and antibacterial activity.
Chemical synthesis ; Physiological Effects of Drugs ; N-acetylanthranilic acid