1.The effect of methyltestosterone on in vitro fertilization outcomes: A randomized clinical trial on patients with low ovarian response
Venus Haj ALIAKBAR ; Fatemeh Davari TANHA ; Firouzeh Akbari ASBAGH ; Mahbod EBRAHIMI ; Zahra SHAHRAKI
Clinical and Experimental Reproductive Medicine 2024;51(2):158-162
Objective:
The aim of this study was to compare the outcomes of in vitro fertilization (IVF) in patients with a poor ovarian response who used methyltestosterone, versus those using a placebo, in an infertility clinic setting.
Methods:
This clinical trial included 120 women who had undergone IVF with intracytoplasmic sperm injection due to poor ovarian reserve and infertility. The study took place at the Yas Infertility Center in Tehran, Iran, between January 1, 2018 and January 1, 2019. In the intervention group, 25 mg of methyltestosterone was administered daily for 2 months prior to the initiation of assisted reproductive treatment. The control group was given placebo tablets for the same duration before starting their cycle. Each group was randomly assigned 60 patients. All analyses were performed using SPSS ver. 23 (IBM Corp.).
Results:
The endometrial thickness in the intervention group was 7.57±1.22 mm, whereas in the control group, it was 7.11±1.02 (