1.Hereditary antithrombin deficiency and hyperhomocysteinemia in venous thromboembolic disease.
Zheng XI-XI ; Bing ZHONG-XING ; Liu BAO
Acta Academiae Medicinae Sinicae 2012;34(6):645-648
Hypercoagulability state is the result of the interplay of genetic predisposition and risk factors. Many key enzymes and reactions in coagulation and anti-coagulation system are involved. Hereditary antithrombin deficiency is one of the major risk factors of venous thromboembolic disease (VTE), whereas hyperhomocysteinemia may also play a role. This article reviews the recent researches on the contributions of these two factors to VTE.
Antithrombin III Deficiency
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complications
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Humans
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Hyperhomocysteinemia
;
complications
;
Venous Thrombosis
;
etiology
3.Internal jugular vein thrombosis with serious cervical necrotizing fasciitis: a case report.
Shujun CHEN ; Yuxuan CHEN ; Linwei ZHAO ; Chao CUI
West China Journal of Stomatology 2016;34(2):215-217
Cervical necrotizing fasciitis (CNF) is an aggressive infection associated with high mortality. Various complications have been described in previous literature. However, internal jugular vein thrombosis is rare in such lesions. We presented a case of internal jugular vein thrombosis caused by CNF and analyzed related literature.
Fasciitis, Necrotizing
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complications
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Humans
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Jugular Veins
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Neck
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Venous Thrombosis
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etiology
7.Postoperative subacute static progressive stretch does not increase the risk of distal lower limb venous thromboembolism.
Jun-Kun ZHU ; Feng-Feng WU ; Rui-Feng YANG ; Fen-Fen XU ; Ya-Li LIN ; Miao-Fang YE
Chinese Journal of Traumatology 2023;26(3):178-182
PURPOSE:
Static progressive stretch (SPS) can be applied to treat chronic joint stiffness. However, the impacts of subacute application of SPS to the distal lower limbs, where deep vein thrombosis (DVT) is common, on venous thromboembolism remain unclear. This study aims to explore the risk of venous thromboembolism events following subacute application of SPS.
METHODS:
A retrospective cohort study was conducted on patients diagnosed with DVT following a lower extremity orthopedic surgery before being transferred to the rehabilitation ward from May 2017 to May 2022. Patients with unilateral lower limb comminuted para-articular fractures, transferred to rehabilitation ward for further treatment within 3 weeks after operation, followed up more than 12 weeks since initial manual physiotherapy, and diagnosed DVT by ultrasound before rehabilitation course were included in the study. Patients with polytrauma, without evidence of previous peripheral vascular disease or incompetence, had medication for thrombosis treatment or prophylaxis before the operation, detected with paralysis due to nervous system impairment, infected after operation during the regime, or with acute progression of DVT were excluded. The included patients were randomized to the standard physiotherapy and the SPS integrated groups for observation. Associated DVT and pulmonary embolism data were collected during the physiotherapy course to compare the groups. SSPS 28.0 and GraphPad Prism 9 were used for data processing. A p < 0.05 was set significant difference.
RESULTS:
In total of 154 patients with DVT participating in this study, 75 of them were treated with additional SPS for postoperative rehabilitation. The participants in the SPS group showed improved range of motion (12.3° ± 6.7°). However, in the SPS group, there was no difference in thrombosis volume between the start and termination (p = 0.106, p = 0.787, respectively), although difference was seen intra-therapy (p < 0.001). Contingency analysis revealed the pulmonary embolism incidence (OR = 0.703) in the SPS group compared to the mean physiotherapy.
CONCLUSION
The SPS technique is a safe and reliable option to prevent potential joint stiffness without aggravating the risk of distal DVT for postoperative patients suffering from relevant trauma.
Humans
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Venous Thromboembolism/prevention & control*
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Venous Thrombosis/etiology*
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Retrospective Studies
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Pulmonary Embolism/complications*
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Lower Extremity
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Risk Factors
8.Prevention from PICC-related venous thrombosis in the upper limbs of malignant tumor patients with moxibustion combined with plucking at Jiquan (HT 1): a randomized controlled trial.
Ling QIU ; Xiao-Yi LIANG ; Yu-Ling ZHENG ; Chun-Xiang LIU ; Xiao-Qing LAI ; Li-Ying ZHU
Chinese Acupuncture & Moxibustion 2022;42(7):741-746
OBJECTIVE:
To observe the clinical effect of moxibustion combined with plucking technique at Jiquan (HT 1) for preventing peripherally inserted central catheter (PICC)-related venous thrombosis in the upper limbs of malignant tumor patients.
METHODS:
A total of 80 malignant tumor patients undergoing PICC were randomized into an observation group and a control group, 40 cases in each one. In the control group, the routine care for PICC was exerted. In the observation group, besides the routine care, moxibustion combined with plucking technique at Jiquan (HT 1) was added. Mild moxibustion was exerted along the venous distribution of PICC (avoiding the entry site) for 10 to 15 min, and then, the circling moxibustion was applied to Quchi (LI 11), Xuehai (SP 10) and Tianfu (LU 3), 3 to 5 min at each acupoint. Finally, plucking technique was given at Jiquan (HT 1) for 5 to 10 min. This combined therapy was intervened since the 2nd day of PICC placement, once daily, 5 times a week, for 3 weeks totally. The incidence of the PICC-related venous thrombosis in the upper limbs was compared between the two groups on day 42 of placement. On day 2, 7, 14, 21, 28, 35 and 42 of PICC placement, the peak systolic velocity (PSV) and the end-diastolic velocity (EDV) of the subclavicular vein on the placement side were observed separately in the two groups.
RESULTS:
The incidence of the PICC-related venous thrombosis in the upper limbs in the observation group was lower than that in the control group (2.5% [1/40] vs 17.5% [7/40], P<0.05). From day 7 to 35 of PICC placement, PSV of the subclavicular vein on the placement side was higher than that on the day 2 of PICC placement in the observation group (P<0.05). On day 28 and 42 of PICC placement, PSV of the subclavicular vein on the placement side was lower than that on the day 2 of PICC placement in the control group (P<0.05). In the observation group, EDV of the subclavicular vein on the placement side was higher than that on the day 2 of PICC placement from day 7 to 28 of PICC placement (P<0.05). In the control group, EDV of the subclavicular vein on the placement side from day 28 to 42 of PICC placement was lower than that on the day 2 of PICC placement (P<0.05). From day 7 to 42 of PICC placement, PSV and EDV of the subclavicular vein on the placement side in the observation group were all higher than those in the control group (P<0.01, P<0.05).
CONCLUSION
The combined treatment of moxibustion with plucking technique at Jiquan (HT 1) can effectively prevent PICC-related venous thrombosis in the upper limbs and improve venous blood flow velocity in malignant tumor patients.
Catheterization, Central Venous/methods*
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Catheterization, Peripheral/adverse effects*
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Humans
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Moxibustion/adverse effects*
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Neoplasms/complications*
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Upper Extremity
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Venous Thrombosis/etiology*
9.A Case of Budd-Chiari Syndrome and Superior Mesenteric Vein Thrombosis in Ulcerative Colitis.
So Young PARK ; Yoon Jae KIM ; In Hae PARK ; Chang Mo MOON ; Chang Whan CHOI ; Sang Kil LEE ; Haeryoung KIM ; Young Nyun PARK ; Tae Il KIM ; Won Ho KIM
The Korean Journal of Gastroenterology 2005;45(3):201-205
Patients with inflammatory bowel disease are at increased risk for thromboembolic complications. Its prevalence rate ranges from 1% to 7% in clinical studies and reaches 39% in autopsy series. The cause of thrombotic complications in inflammatory bowel disease is generally considered to be associated with hypercoagulability. We experienced a case of ulcerative colitis associated with Budd-Chiari syndrome and superior mesenteric vein thrombosis. This rare complication of ulcerative colitis was successfully managed by conventional treatment for ulcerative colitis and anticoagulation therapy.
Adult
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Colitis, Ulcerative/*complications
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English Abstract
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Female
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Hepatic Vein Thrombosis/*complications
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Humans
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Mesenteric Vascular Occlusion/*complications
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Mesenteric Veins
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Venous Thrombosis/*complications
10.An Experience of Axillary-Subclavian Vein Thrombosis after Left Subclavian Vein Catheterization in Polycythemia Vera.
Young Moon JANG ; Baik Hwan CHO ; Jae Chun KIM ; Nam Poo KANG ; Young HWANG
Journal of the Korean Society for Vascular Surgery 1999;15(1):145-152
Deep venous thrombosis (DVT) of the upper extremity has been recently been recognized as being more common than previously reported (probably because of the increasingly frequent use of subclavian venous access). Since the initial descriptions of axillary-subclavian vein thrombosis more than 100 years ago, studies cites a 1.3% to 2.1% incidence of all DVT that occurs in the axillary or subclavian veins. Axillary-subclavian vein thrombosis is commonly associated with significant morbidity. The most serious aspect of morbidity and mortality is pulmonary embolization. Venography or digital subtraction studies are most reliable in allowing detection of thrombosis and Duplex imaging of vein is useful in following the course and assessing the effect of treatment. Early diagnosis and initiation of treatment before thrombus organization are important for successful outcome. Polycythemia vera are at an especially high risk for both thrombotic and hemorrhghic events and postoperative complications. We report a case of axillary-subclavian vein thrombosis after left subclavian vein catheterization in polycythemia vera.
Catheterization*
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Catheters*
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Early Diagnosis
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Incidence
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Mortality
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Phlebography
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Polycythemia Vera*
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Polycythemia*
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Postoperative Complications
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Subclavian Vein*
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Thrombosis*
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Upper Extremity
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Veins*
;
Venous Thrombosis