No abstract available.
Diagnosis* ; Humans ; Venous Thromboembolism*

No abstract available.
Diagnosis* ; Humans ; Venous Thromboembolism*

Humans ; Pulmonary Embolism ; diagnosis ; therapy ; Venous Thromboembolism ; diagnosis ; therapy

China ; epidemiology ; Humans ; Venous Thromboembolism ; diagnosis ; drug therapy ; epidemiology

Anticoagulants ; Humans ; Pulmonary Embolism/diagnosis* ; Recurrence ; Risk Factors ; Venous Thromboembolism

Pulmonary embolism represents the most important complication of deep vein thrombosis, it is of particular concern to surgeons whose patients are prone to develop deep vein thrombosis in the immediate postoperative period. It is a significant source of hospital morbidity and mortality and despite an improved understanding of the pathogenesis diagnosis and management of pulmonary embolism, there continues to be frequent and significant mortality. Most current articles on venous thromboembolism begin with the statement that pulmonary embolism is a common problem and remains a significant cause of mortality in the western countries in spite of recent development in diagnostic and therapeutic modality. We evaluated clinical symptoms, diagnostic modality and therapeutic results of pulmonary embolism which was associated with deep vein thrombosis in 26 cases at Korea University Hospital between 1991 to 1996. Among 26 cases, 20 cases were male and 6 cases were female. The symptoms or signs were dyspnea(76.9%), tachypnea(65.4%), tachycardia(46.2%). The pulmonary perfusion scan was done in 18 cases and 16 cases were observed positive findings. The location of abnormal finding of perfusion scans were 8 both lung(44.4%), 5 right lung(27.7%), 3 left(16.7%). Treatment modalities were heparin, warfain in all cases, thromboembolectomy in 2 cases and insertion of IVC filter in 6 cases. Mortality was 11.5%. In conclusion, pulmonary embolism was not uncommon in Korea and its clinical feature were not greatly differ from literatures. In deep vein thrombosis, major concern and inspection are required to detect pulmonary embolism.
Diagnosis ; Female ; Heparin ; Humans ; Korea ; Male ; Mortality ; Perfusion ; Postoperative Period ; Pulmonary Embolism ; Venous Thromboembolism ; Venous Thrombosis

As the elderly population increases, occurrence of hip fractures has shown a rapid increase, and posttraumatic and postoperative venous thromboembolism can lead to fatal complications. Current prophylactic management includes mechanical and chemical prophylaxis. A 76-year-oldfemale, who was lost to follow-up after diagnosis of pulmonary thromboembolism four years ago, was admitted to our emergency room for a right intertrochanteric fracture. Before the operation, the thromboembolism recurred and was treated with anticoagulation medication. Bipolar hemiarthroplasty and fixation of the greater trochanter with a hook plate were performed 18 days after the trauma. Superficial femoral artery obstruction and venous thromboembolism occurred on the first day after the operation.
Aged ; Diagnosis ; Emergencies ; Femoral Artery* ; Femur* ; Hemiarthroplasty ; Hip Fractures ; Humans ; Lost to Follow-Up ; Pulmonary Embolism ; Thromboembolism ; Venous Thromboembolism*

STUDY DESIGN: A prospective clinical study. PURPOSE: Our objective in the present study was twofold. First, we sought to evaluate the relationship between postoperative venous thromboembolism (VTE) development and concentration of D-dimer to determine the cutoff value in patients who underwent elective spinal surgery. Second, we identified the predictive risk factors for postoperative VTE. OVERVIEW OF LITERATURE: VTE affects the general health of patients and may even cause death. Since the complications of VTE are difficult to predict, the safest and most cost effective diagnostic method should be used in order to confirm a suspected VTE event after spinal surgery. METHODS: This study was performed on 97 patients who underwent elective spinal surgery. The D-dimer assay was carried out on the day before surgery, and on days 1, 3, and 10 following surgery. VTE occurrence and D-dimer levels were compared between the VTE and the control groups. RESULTS: Four patients (4.1%) were diagnosed with deep vein thrombosis and one patient (1%) was diagnosed with a pulmonary embolism. The optimum D-dimer cutoff value on day 3 following surgery in the VTE group was determined to be more than 2.1 microg/mL with a sensitivity of 100% and a specificity of 80.7%. Moreover, the duration of postoperative recumbency was a significant risk factor for the development of VTE in this study. CONCLUSIONS: We have demonstrated that postoperative D-dimer measurements in patients who underwent elective spinal surgery can provide a complementary diagnostic screening for VTE during the first week after surgery.
Diagnosis* ; Humans ; Mass Screening ; Plasma* ; Prospective Studies ; Pulmonary Embolism ; Risk Factors ; Sensitivity and Specificity ; Spine ; Venous Thromboembolism* ; Venous Thrombosis

BACKGROUND: D-dimer is a specific marker of secondary fibrinolysis. D-dimer assay is widely used in the diagnosis of disseminated intravascular coagulation, deep vein thrombosis, pulmonary embolism, and arterial thromboembolism. Enzyme linked immunosorbent assays have been validated as the reference method for plasma D-dimer measurement, but it took long time. We evaluated the analytical performance of new automated coagulation system, ACL TOP, for quantification of D-dimer. METHODS: The total plasma D-dimer concentrations were measured by Nycocard and ACL TOP. To test the linearity, a serial dilution samples were prepared and measured. Between run precision of the ACL TOP D-dimer assay was evaluated with HemosIL D-Dimer controls for 20days. The correlation was evaluated using 75 plasma samples from patients. ACL TOP was evaluated according to CLSI guidelines. RESULTS: ACL TOP showed good linearity (r=0.9996) and between run coefficient of variation was within 4.0%. Coefficient of correlation between Nycocard and ACL TOP was 0.798. Positive concordance rate of ACL TOP was 67%, and negative concordance rate of ACL TOP was 80%. CONCLUSIONS: Since the ACL TOP showed a satisfactory precision, linearity, and comparative high correlation with Nycocard, and is more convenient and automatic than the Nycocard, it should be potentially beneficial in the clinical laboratories.
Diagnosis ; Disseminated Intravascular Coagulation ; Fibrinolysis ; Humans ; Plasma ; Pulmonary Embolism ; Thromboembolism ; Venous Thrombosis

A newly reported, variant form of venous thromboembolism (VTE), named as "eThrombosis"1), occurred to a patient who was a prolonged sitting position at computer. The patient fortunately recovered from the disease through the early diagnosis and treatment. Recently, the author experienced a new case of a 24-year-old Korean man who died due to "eThrombosis"after playing an internet computer game continuously for about 85 hours. Therefore, the author would like to warn heavy computer users of the risk of the "eThrombosis", as they might also have high risk factors based upon this case, and inform this at-risk group that sitting for a long time at the computer results in an immobility that is a new greater risk factor of life-threatening VTE.
Early Diagnosis ; Humans ; Internet ; Pulmonary Embolism* ; Risk Factors ; Venous Thromboembolism ; Video Games ; Young Adult