No abstract available.
Vasospasm, Intracranial*

No abstract available.
Cerebral Infarction ; Vasospasm, Intracranial

No abstract available.
Intracranial Aneurysm* ; Surgical Instruments* ; Vasospasm, Intracranial*

Numerous approaches to the prevention and treatment of cerebral vasospasm have been made. Its etiology and pathogenesis are still not well understood, and there is no animal model that duplicates all of the key aspects of human cerebral vasospasm. It is therefore not surprising that most of the attempts to prevent or treat this condition have failed. Since 1980, there has been some progress toward the satisfactory management of this detrimental condition, but much remains to be done. In the present article, experimental therapies are examined in detail, followed by a review of promising new treatments presently in clinical trials and generally accepted management in reducing the ischemic complications related to cerebral vasospasm.
Humans ; Models, Animal ; Therapies, Investigational ; Vasospasm, Intracranial

No abstract available.
Latex* ; Polystyrenes* ; Potassium Channels* ; Potassium* ; Vasospasm, Intracranial*

Somatosensory evokd responses(SSERs) and auditory evoked responses(AERs) were studied in 33 patients with cerebral aneurysms and arteriovenous malformations(AVMs) to see if these tests were useful indicators of cerebral vasospasm. 7/21 had abnormal SSER and 5/28 an abnormal AER. The SSER was abnormal in 4/7 patients with severe vasospasm but in only 1/13 without spasm or with mild or moderate spasm. Abnormal SSERs in patients with severe vasospasm indicated a poor prognosis. Abnormalities on the SSER and AER correlated best with the degree of clinical deficit. These tests seemed insufficiently sensitive to reliable detect impending ischemia.
Arteriovenous Malformations* ; Humans ; Intracranial Aneurysm* ; Ischemia ; Prognosis ; Spasm ; Vasospasm, Intracranial

The literature concerning cerebral vasospasm associated with subarachnoid hemorrhage(SAH) due to ruptured intracranial aneurysm contains no definitive study of patients to determine whether there is (1) any clinical picture consistently present coincident with known cerebral vasospoasm, (2) any relationship between mortality and known vasospasm, and (3) any relationship between serious brain damage(morbidity) and known vasospasm. To answer these important questions, experience with 138 consecutive acute SAH patients due to ruptured intracranial aneurysm was studied. The results were (1) The vasospasm was seen in 61 patients(44.2%) and the clinical vasospasm was seen in 41 patients(29.8%);(2) The average interval between last SAH and vasospasm was 8.3 days;(3) The most common neurological deficit was a hemiparesis or a hemiplegia;(4) There is no relationship between mortality and vasospasm.
Brain ; Humans ; Intracranial Aneurysm* ; Mortality ; Paresis ; Vasospasm, Intracranial

The literature concerning cerebral vasospasm associated with subarachnoid hemorrhage(SAH) due to ruptured intracranial aneurysm contains no definitive study of patients to determine whether there is (1) any clinical picture consistently present coincident with known cerebral vasospoasm, (2) any relationship between mortality and known vasospasm, and (3) any relationship between serious brain damage(morbidity) and known vasospasm. To answer these important questions, experience with 138 consecutive acute SAH patients due to ruptured intracranial aneurysm was studied. The results were (1) The vasospasm was seen in 61 patients(44.2%) and the clinical vasospasm was seen in 41 patients(29.8%);(2) The average interval between last SAH and vasospasm was 8.3 days;(3) The most common neurological deficit was a hemiparesis or a hemiplegia;(4) There is no relationship between mortality and vasospasm.
Brain ; Humans ; Intracranial Aneurysm* ; Mortality ; Paresis ; Vasospasm, Intracranial

Cerebral vasospasm leading to delayed ischemic neurological deficits (DINDs) is one of the most serious complications after aneurysmal subarachnoid hemorrhage (SAH). There are many evidence, against which demonstrate the role of angiographically confirmed vasospasm as the sole cause of DINDs. The authors review literatures that support a potential role of thromboembolism as a possible cause of DINDs after aneurysmal SAH. Although there is some controversy regarding the relation between the cerebral vasospasm in large arteries and cerebral ischemia, vasospasm still remains one of the primary causes of DINDs. In addition, thromboembolism intensifies or supplements the effects of vasospasm as a possible alternative.
Aneurysm* ; Arteries ; Brain Ischemia ; Subarachnoid Hemorrhage* ; Thromboembolism* ; Vasospasm, Intracranial

Cerebral vasospasm is one of the most serious complication after subarachnoid hemorrhage due to aneurysmal rupture. To date, the treatment of vasospasm remains unsatisfactory in a large numbers of cases in spite of recent therapeutic advances. Prompt diagnosis of this complication, before the establishment of lasting ischemic damage, should obviously improve the results of treatment. The possibility of predicting which patients will develop vasospasm, constitutes a further advance in the management of this complication. In this study, the value of the computed tomographic scan for the prediction of vasospasm was investigated in a consecutive series of 67 patients submitted to computed tomography within 7 days of the most recent subarachnoid hemorrhage.
Aneurysm* ; Diagnosis ; Humans ; Rupture* ; Subarachnoid Hemorrhage* ; Vasospasm, Intracranial*