Leukocytoclastic vasculitis (LCV) usually presents palpable purpura characterized by inflammation of vessel walls and fragmentation of nuclei. Various conditions can cause LCV, and it can be induced by influenza A virus infection. We report a 2-yr-old Korean girl who presented palpable purpuric and hemorrhagic lesions with fever. She was diagnosed as LCV by skin biopsy, and influenza A virus was isolated from nasopharyngeal swab. She was treated with oseltamivir (Tamiflu(R)) and prednisolone with dramatic effect of vasculitis and fever.
Anti-Inflammatory Agents/therapeutic use ; Antiviral Agents/therapeutic use ; Child, Preschool ; Female ; Fever/etiology ; Humans ; Influenza A virus/*genetics/isolation & purification ; Influenza, Human/*complications/drug therapy/virology ; Nasopharynx/virology ; Oseltamivir/therapeutic use ; Prednisolone/therapeutic use ; Reverse Transcriptase Polymerase Chain Reaction ; Skin/pathology ; Vasculitis, Leukocytoclastic, Cutaneous/*diagnosis/drug therapy/etiology