1.Leukocytoclastic Vasculitis Associated with Influenza A Virus Infection.
Hyo Jin LEE ; Dong Hoon SHIN ; Jong Soo CHOI ; Ki Hong KIM
Journal of Korean Medical Science 2012;27(12):1601-1603
Leukocytoclastic vasculitis (LCV) usually presents palpable purpura characterized by inflammation of vessel walls and fragmentation of nuclei. Various conditions can cause LCV, and it can be induced by influenza A virus infection. We report a 2-yr-old Korean girl who presented palpable purpuric and hemorrhagic lesions with fever. She was diagnosed as LCV by skin biopsy, and influenza A virus was isolated from nasopharyngeal swab. She was treated with oseltamivir (Tamiflu(R)) and prednisolone with dramatic effect of vasculitis and fever.
Anti-Inflammatory Agents/therapeutic use
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Antiviral Agents/therapeutic use
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Child, Preschool
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Female
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Fever/etiology
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Humans
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Influenza A virus/*genetics/isolation & purification
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Influenza, Human/*complications/drug therapy/virology
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Nasopharynx/virology
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Oseltamivir/therapeutic use
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Prednisolone/therapeutic use
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Reverse Transcriptase Polymerase Chain Reaction
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Skin/pathology
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Vasculitis, Leukocytoclastic, Cutaneous/*diagnosis/drug therapy/etiology