A measure of the microalbuminuria by the immunoturbidimetric, a semi- quantative method of microalbuminuria with Micral- test dipstick and renal biopsy were undertaken for evaluation of prevalence of microalbuminuria in diabetes mellitus and the early predictive value of microalbuminuria for detecting diabetic nephropathy. The results of our study showed: prevalence of MAU was 33.3% and 31.6% in INDD and NINDD patients respectively. For semi-quantative method of microalbuminuria, when it was done two consecutive times, the sensitivity and the spectively. A close correlation between the severity of renal lesions and the MAU value was noticed when we compared the MAU thresholds> 20 mg/min with the results of renal involvement in diabetes. The Micral -test dipstick for semi-quantative of microalbuminuria could be used as an alternative method, if a measure of the MAU is not readily available
Diabetic Nephropathies ; diagnosis

Studying 338 new onset diabetic patients for 2 years, aged 30 to 69 years, were treated at Bach Mai Hospital from February to December 2004. All the patients have clinical examination and blood urine laboratory tests as well as vascular investigations. Results showed that characteristics of new onset type 2 diabetic patients as follow: BMI index is in normal range (22.92  2.66), however the waist/hip index is high (0.89  0.069). 22.6% of patients with type 2 diabetic are hypertensive. All the patients had indices above normal levels such as the fasting glycemia, after meal glycemia, HbA1c, serum cholesterol and triglyceride. Although 100% of patients had the normal results of peripheral vascular clinical examination, the vascular Doppler sonography showed a marked decrease of FMD and a significant greater thickness of carotid artery intimamedia
Diabetes Mellitus, Type 2 ; Clinical Medicine ; Laboratories

Longitudinal study and correlation analysis was performed on 338 patients with diabetes type 2 at National Hospital of Endocrinology and Department of Endocrinology and Diabetes of Bach Mai Hospital between 2/2002 and 12/2004. Patients were divided into 2 groups. The first group included 238 patients were control strictly for glycemia and risk factors by treatment target. 100 patients followed treatment regimen without strict control were served as control group. All patients had FMD measured before and after receiving treatment. Results: fasting glycemia < 7mmol/l, post prandial glycemia< 10mmol/l, blood pressure >130/80 - <140/90, total cholesterol <5.3mmol/l, LDL-C < 3.4mmol/l, TG<2.3mmol/l, HDL-C<0.9mmol/l. Strictly control for glycemia and risk factors help improve FMD significantly. In the first group, the FMD has significantly increased after receiving treatment in comparison with the control group
Diabetes Mellitus, Type 2 ; Risk factors ; Therapeutics

Background: High glucose level can cause many serious complications, especially for type 2 diabetic patients. Poorly blood glucose control in type 2 diabetic patients usually induces serious complications. Objective: (1) To evaluate blood glucose control state and (2) To describe affected factors to blood glucose control in type 2 diabetic patients. Subjects and method: We carried out a survey on blood glucose control in 104 type 2 diabetic patients (based on HbA1c results), admitted to Dept of Endocrinology, Bach Mai Hospital from December 2005 to April 2006. 73.1 % of patients is female, average age is 63.4 years old, 57.7% has hypertension, and 62.5% has diabetes for \ufffd?5 years. Results:Blood glucose is poorly controlled in 80.8% (HbA1C > 7.5%), and good controlled in only 12.5% patients (HbA1C < 6.5%). Several affected factors are identify, such as patients were not educated and/or do not perform correctly nutritional and exercise therapy (48.1 %); not compliant with drug treatment; or not measure regularly blood glucose; and long duration of diabetes (p < 0.01). Conclusions: (1) Blood glucose in majority of type 2 diabetic patients is poorly controlled. (2) Factors affected are non - compliance with therapy, irregularly blood glucose measurement and long duration of diabetes.
Diabetes Mellitus ; Type 2/ therapy