Review and update some knowledge of alpha feto-protein (AFP) value in the diagnosis, prognosis and management of patients with hepatocellular carcinoma (HCC), and the role of AFP in monitoring of response to medical and surgical treatments. Serum AFP tests give sensitivity of 50% and specificity >90% at cut-off value of 500 ng/ml in the diagnosis of HCC in patients who had underlined hepatic diseases
Carcinoma, Hepatocellular ; Liver ; Liver Neoplasms

The biochemical changes among patients with hepatocellular carcinoma were various and common in which reduction of albumin synthesis (61%), reversion of A/G ratio (58%), bilirubinemia (21%), increases of SGOT (91%) and SGPT (82%) and these increases were direct proportional with progress of disease
Carcinoma, Hepatocellular ; Metabolism

A study carried out on patients with hepatocellular carcinoma in Hue hospital during 2000-2001. The obtained results as following: the average age of patients with hepatocellular carcinoma with positive HBVDNA was lower than this of patients with the hepatocellular carcinoma with positive HCVRNA. While the rate of male/female among group of hepatocellular carcinoma with positive HBVDNA was higher than this among group of hepatocellular carcinoma with the positive HCVRNA. The clinical and biological symptoms and ultrasound related with the cirrhosis in the group of hepatocellular carcinoma with the positive HCVRNA were more frequent than these in the group of hepatocellular carcinoma with positive HBVDNA were. There was difference of survival rate in the end of the sixth month between 2 groups but there was no difference in the end of the ninth month.
Carcinoma, Hepatocellular ; Ultrasonography

A study on patients with hepatocellular carcinoma in HuÕ hospital during 1990-1995 and 2000 has shown that the disease was increasingly during 1990-2000, the morbidity rate was predominant higher than this in women, and average age of patients was reduced. The major etiological agent was hepatitis B virus. The alcohol played a combined role with hepatitis B virus in the hepatocellular carcinoma. The role of hepatitis C virus was not statistical significant.
Carcinoma, Hepatocellular ; Hepatitis C virus ; Hepatitis B virus

Studying on 60 patients with upper digestive hemorrhage to determine the causes of disease showed that duodenal ulceration (26.7%), peptic ulceration (21.7%), gastritis (11.9%), and gastroduodenal ulceration (8.3%). Mallory - Weiss (8.3%), esophageal venous rupture (8.3%) peptic cancer (6.6%), pancreatic head cancer compressing the O2 duodenum (1.6%), datric polyps (1.6%) and unidentified cause (5%).
Hemorrhage ; Gastrointestinal Hemorrhage

Between 1990 to 1994, 217 patients were diagnosed with biliary ascariasis by ultrasonography. It was showed that biliary ascariasis is a pathological condition with excess incidence. Treatment in complicated or pregnant cases is difficult and costly. Some factors, especially female gender, pregnancy, and pH level of biliary fluid can influence favorably to the migration of ascarid. Ascarid infection density does not affect to the relapse frequency. Use helminthics early with single dose can provide the pain relief rapidly, reduce the rate of complication and avoid overuse the anti-spasmodics. The patients with history of biliary asariasis relapses should be followed-up and treated actively.
Ascariasis ; ultrasonography ; therapeutics

The anterior interosseous artery (AIA) plays an essential role in designing the posterior interosseous forearm flap (P.I.F.F). Understanding about anatomy of this artery permit us to find us to find out new solutions to design the P.I.F.F. in situations at which there are variations of the PIA. Objectives: (I) to evaluate the role of the anterior interosseous artery in the blood supplying to the posterior forearm region; (II) assessing the importance of anterior interosseous artery in designing the posterior interosseous forearm flap. Methods: 27 forearms of adults obove 25 years old, including 25 forearms fixed in formalin 4% and 2 fresh forearms, are objects for us to expose the AIA and PIA by different techniques. Results: There are 2-5 perforating branches of the AIA to the deep muscular layer of posterior. They connect to each other and to the muscular branch of the PIA, and their diameter becomes much larger in two cases of absence of the PIA. Branches from this series of arterial anastomoses distribute also to the skin of inferior half of posterior forearm. The posterior terminal branche of the AIA divides into the medial and recurrent branch. These two branches ascend and anastomose with the PIA and the muscular branch of the PIA, respectively. The medial branch of the posterior terminal branch is absent or disconnected with the PIA at two other cases. Conclusion: Our results indicate that the AiA supplies the inferior half and the deep muscular layer of the posterior forearm. The posterior interosseous forearm flap can still be raised in situations at which the posterior terminal branch of AIA communicates with the dorsal carpal arcus but not with the PIA and the PIA is absent.
Surgical Flaps, Surgery , Arteries

Background: Hepatitis B is a potentially serious form of liver inflammation due to infection by the hepatitis B virus (HBV). It occurs in both rapidly developing (acute) and long-lasting (chronic) forms, and is one of the most common chronic infectious diseases worldwide. HBV infection is very common in Thua Thien \ufffd?Hue. Objectives:. Our study is aimed to assess the efficacy and safety of Adefovir dipivoxil(ADV) in patients with HBeAg positive chronic hepatitis B .. Subjects and method: Design of study: Prospective; 36 patients with HbeAg (+) chronic B hepatitis were enrolled in this study, all patients were treated with Adefovir dipivoxil in 24 months at Hue University Hospital from October 2004 to September 2006 . Results: The rate of normalization of ALAT is 50 % after 6 months, 66.66% after 12 months and 69.44% after 24 months. The rate of HbeAg seroconversion is 11.11 % after 12 months and 30.55% after 24 months. This rate is Significantly higher in group of patients having the activity of SePT between 5 - 10 normal (58.33%). The rate of phenotypic resistance is only 2.77% after 12 months and 8.33% after 24 months. The tolerance is generally good\r\n', u'even in long - term treatment and no complication of renal\r\n', u'insufficiency was found. Conclusion: ADV appears an effective and safe in patients with HBeAg(+) chronic hepatitis. \r\n', u'
Hepatitis B ; Chronic/ pathology ; therapy ; Adenine/ analogs & ; derivatives

The main cause of the chronic pancreatitis were the chronic alcoholism (64%). The other etiology were hyperlipiderma (8%), malnutriation especially 16% patients had clinical biological and histogical evidences related protein malnutriation. The clinical condition were various: the abdominal pain were most common (92%). The position of pain, regardless the acute pain attack can help the diagnosis. The most comon complications were the disorder of glucose toleration (48%) and false cyst in the pancreas (32%), disorder of exocrine functions (24%) in long term studied group.
Pancreatitis, Chronic ; etiology ; diagnosis

Objectives: Assess some disorder of hemostasis in the patient of cirrhosis; Estimate the correlation between these disorders and the Child-Pugh score. Methods: 30 patients of cirrhosis diagnosed upon the clinical, biological and imaging criteria, in the Department of HepatoGastroEnterology, Hue Central Hospital, from January to October 2000. Results and conclusion: The frequency of the disorder of hemostasis in the patients of cirrhosis is about 92%, the most frequent of these disorders is the prolongation of prothrombine time (83.3%). A diminution of fibrinogen concentration was found in 46.7% the cases. Significant prolongation of the time of Howell and Cephalin - Kaolin time are found respectively in 53.4% and 40%. Thrombocytopenia occurs in only 6.7%. Clinical manifestations don't reflex exactly the disorders of hemostasis, bleeding in the peritoneal cavity was found in 13.3%. There isn't any strict correlation between Child-Pugh score (CPS) and any of the hemostasis disorders. Apart from a medium correlation between CPS and prothrombin time (r=0.56, p<0.05) and concentration of fibrinogen (r=0.62, p<0.05) and minimal correlation between CPS and time of Howell (r=0.32, p<0.05) and Time of Cephalin - Kaolin (r=0.30, p>0.05)
Fibrosis ; Blood Coagulation Disorders