We conducted a retrospective analysis of 394 patients with uveitis seen at Kyung Hee University Medical Center from January 1982 to June 1987 to determine the frequency of occurence and to study the clinical characteristiscs of various form of uveitis. The results were as follows; 1. In classification of uveitis by location, 309 patients(78.4%) were anterior uveitis, 41 patients(10.4%) were posterior uveitis, 31 cases(7.9%) occurred as panuveitis. Pars planitis accounted for 13 cases(3.3%). Anterior uveitis was the most common causes of uveitis. 2. In cases of anterior uveitis, 127 cases(32.7%) were idiopathic iridocyclitis, 121 cases(30.7%) were traumatic iridocyclitis. In cases of posterior uveitis, Tuberculous uveitis was seen in 11 cases(2.8%), and Toxoplasmic chorioretinitis occured 10 cases(2.5%). In case of panuveitis, Behcet's disease was observed 10 patients(2.5%), and was the most common cause of panuveitis, pars planitis accounted for 13 cases(13.3%). 3. In aspect of age of uveitis, the peak age was 16~45 yrs.(60.6%). In case of anterior uveitis and pars planitis, peak age group was 16~45 yrs. In case of posterior uveitis and panuveitis, peak age group was 31~60 yrs. 4. In clinical characteristics of uveitis by location, anterior uveitis occurred at mostly younger age than did any uveitis(27.8 yrs.) in average age of diagnosis. In sex ratio, male patient of pars planitis predominated with over 3 times number of female patient. In the average duration of illness from the date of first symptom to date of first recorded quiescence, anterior uveitis was mostly shorter duration than did any uveitis(1.1 Mon.). 5. In the evaluation of laterality, all cases showed binocular equal distribution except pars planitis. 6. The largest number of complication was showed in panuveitis. 7. The most common symptom of uveitis was visual disturbance.
Academic Medical Centers ; Chorioretinitis ; Classification* ; Diagnosis ; Female ; Humans ; Iridocyclitis ; Male ; Panuveitis ; Pars Planitis ; Retrospective Studies ; Sex Ratio ; Telescopes ; Uveitis* ; Uveitis, Anterior ; Uveitis, Posterior

Uveitis is a comprehensive term that indicates the inflammation of not only the uvea but also its adjacent tissues, and its etiology, clinical feature and prognosis are various. Uveitis can be classified in a variety of ways and this fact makes it difficult to compare each result. So we classified uveitis by the location with the method of Henderly, D.E.(1986): ant-, post-, intermediate- and panuveitis. We determined the frequency of occurrence, etiology and clinical characteristics of various forms of uveitis in Korea. We conducted a retrospective analysis of 683 patIents with uveitis seen at Seoul National University Hospital from January 1978 to December 1987 and the results were as follows. 1. 192 cases(29.1%) occurred as anterior uveitis, 218 cases(31.9%) as posterior uveitis, 166 cases(24.3%) as panuveitis and 107 cases(15.7%) as pars planitis: Posterior uveitis was the most common form of uveitis. 2. In cases of anterior uveitis, 142 cases(70.4%) were idiopathic, traumatic uveitis was seen in 18 cases(9.4%). In posterior uveatis, III cases(50.9%) were idiopathic, retinal vasculitis including Eales' disease in 60 cases(27.5%) and toxo-plasmosis in 23 cases(10.6%). In cases of panuveitis, idiopathic form occurred in 80 cases(48.2%), Behcet's disease in 41 cases(24.7%): Idiopathic form was the most common entity in all locations of uveitis.
Classification ; Humans ; Incidence ; Inflammation ; Korea* ; Panuveitis ; Pars Planitis ; Prognosis ; Retinal Vasculitis ; Retrospective Studies ; Seoul ; Uvea ; Uveitis* ; Uveitis, Anterior ; Uveitis, Posterior

This study was undertaken to evaluate the effectiveness of pars plana vitrectomy in pars planitis and posterior uveitis. We performed pars plana vitrectomies in consecutive series of 31 eyes with pars planitis and posterior uveitis that were complicated with vitreous opacities, epiretinal membrane formation, tractional retinal detachment and posterior subcapsuIar cataract. Postoperatively improvement of visual acuity, 2 lines or more in Snellen chart, was noted in 19 eyes (61.2%) with a mean follow-up of 21 months. The inflammatory cells were not visible in anterior chamber or anterior vitreous after 1 month thereafter. In three patients, however, the postoperative visual acuities were worse due to preoperatively combined cystoid macular edema, macular pucker and tractional retinal detachment. We believe early pars plana vitrectomy before the formation of epiretinal membrane is an important factor in minimizing and postoperative complications.
Anterior Chamber ; Cataract ; Epiretinal Membrane ; Follow-Up Studies ; Humans ; Macular Edema ; Pars Planitis* ; Postoperative Complications ; Retinal Detachment ; Traction ; Uveitis, Posterior* ; Visual Acuity ; Vitrectomy*

This study was undertaken to evaluate the effectiveness of pars plana vitrectomy in pars planitis and posterior uveitis. We performed pars plana vitrectomies in consecutive series of 31 eyes with pars planitis and posterior uveitis that were complicated with vitreous opacities, epiretinal membrane formation, tractional retinal detachment and posterior subcapsular cataract. Postoperatively improvement of visual acuity, 2 lines or more in Snellen chart, was noted in 19 eyes(61.2%) with a mean follow-up of 21 months. The inflammatory cells were not visible in anterior chamber or anterior vitreous after 1 month thereafter. In three patients, however, the postoperative visual acuities were worSe due to preoperatively combined cystoid macular edema, macular pucker and tractional retinal detachment. We believe early pars plana vitrectomy before the formation of epiretinal membrane is an important factor in minimizing and postoperative complications.
Anterior Chamber ; Cataract ; Epiretinal Membrane ; Follow-Up Studies ; Humans ; Macular Edema ; Pars Planitis* ; Postoperative Complications ; Retinal Detachment ; Traction ; Uveitis, Posterior* ; Visual Acuity ; Vitrectomy*

Although intraocular involvement in Hodgkin's disease is infrequent, there were reported iridocyclitis, exudative retinal detatchment, retinal hemorrhage, necrotizing retinitis, anterior and posterior uveitis, perivascular chorioretinitis. We report a 61 years old male patient with Hodgkin's disease who developed retinal lesion with decreased visual acuity in his right eye during a period of quiscence in his disease, 10 months since diagnosed. On first ophthalmic examination, best corrected vision of right eye was 0.6 and 1.0 on left eye. Fundus examination of the left eye was normal; however, the right eye revealed cotton wool patches, retinal edema, and intraretinal hemorrhage along the superior temporal venules. Fluorescein angiography showed blockage of choroidal flush in early phase and focal area of hyper fluorescence with perivascular leakage of dye in late phase. The results of TORCH test were negative, and the patient didn't have hypertension, diabetes mellitus, and bleeding tendency. Therefore we this case presumed perivascular retinitis associated with Hodgkin's disease.
Chorioretinitis ; Choroid ; Diabetes Mellitus ; Fluorescein Angiography ; Fluorescence ; Hemorrhage ; Hodgkin Disease* ; Humans ; Hypertension ; Iridocyclitis ; Male ; Middle Aged ; Papilledema ; Retinal Hemorrhage ; Retinaldehyde ; Retinitis* ; Uveitis, Posterior ; Venules ; Visual Acuity ; Wool

PURPOSE: Retisert(TM) (fluocinolone acetonide implant) has recently been approved for clinical use in patients with noninfectious posterior uveitis. We report a patient with intractable chronic Behcet's panuveitis who underwent Retisert(TM) implantation and showed a favorable outcome. METHODS: A 30-year-old male affected with intractable Behcet's uveitis of both eyes for over one year which did not respond to oral steroids and immunosuppressants; subcutaneous interferon injection caused undesirable side effects such as impotency and pyrexia. Initial visual acuities were 20/1000 in the right eye and 20/100 in the left eye, and both eyes showed severe panuveitis with posterior subcapsular cataract, especially in the right eye. The subtenon triamcinolone injection was performed in the right eye, which was only effective to anterior uveitis, and Retisert(TM) was implanted in the right eye after the cataract operation. Two months later the visual acuity increased to 20/25, and the inflammation was totally controlled. There were no ocular or systemic adverse events. CONCLUSIONS: Retiserttrade mark is a fast, effective, and safe treatment for chronic, non.infectious posterior uveitis.
Adult ; Cataract ; Eye ; Fever ; Fluocinolone Acetonide ; Humans ; Inflammation ; Interferons ; Male ; Panuveitis ; Steroids ; Triamcinolone ; Uveitis ; Uveitis, Anterior ; Uveitis, Posterior ; Visual Acuity

Sarcoidosis is a granulomatous disease which frequently involves eyes and adnexal tissues. Its prevalence of ocular involvement is reported as about 20%, although it varies widely according to authors, from 12% to 73%. Ocular sarcoidosis is present as various forms - uveitis, conjunctival involvement, optic nerve involvement, and orbital involvement. All the forms of uveitis - anterior uveitis, intermediate uveitis, posterior uveitis and panuveitis - can be shown in sarcoidosis. Because clinical manifestation, prognosis and treatment are determined by the location of uveitis, it is important to classify uveitis. Conjunctival involvement is not a sight-threatening condition in general, its diagnostic value may be of use. Optic nerve is the most commonly involved cranial nerve, which can impair vision. Subjects with visual impairment without any evidence of uveitis, optic nerve involvement should be suspected. Orbital involvement, especially lacrimal gland involvement is common, and it may cause mass-effect. Besides systemic administration of drugs, there are several localized treatments for ocular sarcoidosis - topical eye drops, intra/peri-ocular injection of agents.
Cranial Nerves ; Granuloma ; Lacrimal Apparatus ; Ophthalmic Solutions ; Optic Nerve ; Orbit ; Panuveitis ; Prevalence ; Prognosis ; Sarcoidosis* ; Uveitis ; Uveitis, Anterior ; Uveitis, Intermediate ; Uveitis, Posterior ; Vision Disorders

Nd-YAG laser is known as a safe and effective treatment for posterior capsular opacity after cataract surgery. We studied the ocular complications after Nd-YAG laser treatment in uveitis patients. From January 1991 to December 1996, we retrospectively investigated the complications of uveitis in 22 persons(25 eyes) after Nd-YAG laser posterior capsulotomy, and also investigated that of nonuveitis in 563 persons(635 eyes) as a control group. The uveitis cases consisted of six anterior uveitis, eight intermediate uveitis, seven Behcet`s syndromes, three panuveitis, and one posterior uveitis. In the uveitis group, the complications(18 eyes) consisted of three retinal detachments, one giant retinal tear, three glaucoma, two aggravations of uveitis, two vitreous opacities, one retinal emorrhage, one proliferative vitreoretinopathy, one hyphema, and four transient high intraocular pressures(IOP), and in the control group, it consisted of two subluxations of intraocular lens(IOL), three glaucomas, one retinal tear, three transient high IOPs, two vitreous opacities, two retinal hemorrhages, three macular holes, two retinal detachments, and five cystoid macular edemas. From our experience, the incidence of complications after Nd-YAG laser posterior capsulotomy in uveitis was higher than that in nonuveitis. It was also noted that it is necessary to follow up thoroughly the complications after Nd-YAG laser posterior capsulotomy in uveitis patients.
Cataract ; Follow-Up Studies ; Glaucoma ; Humans ; Hyphema ; Incidence ; Lasers, Solid-State* ; Macular Edema ; Panuveitis ; Posterior Capsulotomy* ; Retinal Detachment ; Retinal Hemorrhage ; Retinal Perforations ; Retinaldehyde ; Retrospective Studies ; Uveitis* ; Uveitis, Anterior ; Uveitis, Intermediate ; Uveitis, Posterior ; Vitreoretinopathy, Proliferative

PURPOSE: This study was undertaken to evaluate the clinical results of pars plana vitrectomy on posterior segment complications in posterior uveitis. METHODS: We reviewed the records of 20 eyes of 19 uveitis patients who were followed up for 6 months or more after vitrectomy. RESULTS: The mean follow-up period was 20 months. Final visual acuity improved in 10 eyes (50%), was maintained in 6 (30%), and decreased in 4 (20%). The mean improvement of vision was 1.6 lines (p=0.019). Detached retina was reattached in 8 (80%) among the 10 eyes with primary surgery. Postoperative complications were cataract (7 eyes), macular degeneration (2 eyes), retinal detachment (2 eyes), and recurrence (1 eye). CONCLUSIONS: These results suggest that pars plana vitrectomy may be a safe and effective treatment for posterior segment complications in posterior uveitis, but that early and complete vitrectomy should be considered for a better visual prognosis.
Cataract ; Follow-Up Studies ; Humans ; Macular Degeneration ; Postoperative Complications ; Prognosis ; Recurrence ; Retina ; Retinal Detachment ; Uveitis ; Uveitis, Posterior* ; Visual Acuity ; Vitrectomy*

PURPOSE: To evaluate the therapeutic effect and safety of mycophenolate mofetil (MMF) on chronic uveitis in Korean patients. METHODS: This study included 25 patients with chronic uveitis who used MMF and were followed up more than 6 months in 2 referral centers from 2010 to 2014. The medical records were analyzed retrospectively. The therapeutic effect was assessed based on control of inflammation, corticosteroid sparing effects, and discontinuation of MMF, and the safety was assessed based on side effects. Control of inflammation was defined as no active inflammation observed on at least 2 consecutive visits 28 days apart or more. RESULTS: The 25 patients consisted of 18 males and 7 females. The mean age of the patients was 47.52 years. The etiology of uveitis was as follows: Behcet's disease in 15 patients (60%), Vogt-Koyanagi-Harada disease in 4 (16%), sympathetic ophthalmia in 2 (8%), systemic lupus erythematosus in 1 (4%), and idiopathic uveitis in 3 (12%). Anatomic classification was anterior uveitis in 20% and posterior uveitis or panuveitis in 80% of patients. Complete control of inflammation was achieved in 44% and 50% of patients within 6 months and 1 year, respectively. Systemic corticosteroid dosage was reduced to 10 mg of prednisone or less while maintaining sustained control of inflammation in 36% and 45% of patients for 6 months and 1 year, respectively. MMF was discontinued in 3 patients (12%) due to side effects and in 2 patients (8%) due to lack of effectiveness. CONCLUSIONS: MMF was effective and side effects were uncommon when managing chronic uveitis in Korean patients.
Classification ; Female ; Humans ; Inflammation ; Lupus Erythematosus, Systemic ; Male ; Medical Records ; Ophthalmia, Sympathetic ; Panuveitis ; Prednisone ; Referral and Consultation ; Retrospective Studies ; Uveitis* ; Uveitis, Anterior ; Uveitis, Posterior ; Uveomeningoencephalitic Syndrome