Despite of much advances in the design of the IOL and the method of the sterilization and the techniques in ophthalmic surgery, disastrous complications following cataract extraction have been reported occasionally. Such complications may occur with or without IOL implantation, and may be induced by artificial lens itself or by indirect effect of the lens such as mechanical trauma. A pseudophakic eyeball which was implanted iris-supported IOL 6 years ago was enucleated due to intractable ocular pain, and the eyeball exhibited a localized inflammation in the anterior uvea especially in iris. From those findings we could suspect a mechanical trauma of the IOL, that might cause noninfectious inflammation. The complication of the cataract extraction is reviewed with histopathologic findings.
Cataract Extraction ; Inflammation ; Iris ; Sterilization ; Uvea

Sympathetic ophthalmia is a rare, diffuse, granulomatous inflammation of the entire uvea, usually bilateral, which occurs days, months, or years after penetrating ocular injury or intraocular surgery. This presented case was a 34 years old male patient injured his left eye suspecting a scleral laceration. The exciting eye(left) was eviscerated 8 days after injury and sympathetic eye(right) was developed sympathetic ophthalmia 8 weeks after injury. A brief review of the related literatures is presented.
Adult ; Humans ; Inflammation ; Lacerations ; Male ; Ophthalmia, Sympathetic* ; Uvea

Sympathetic ophthalmia is rare, bilateral, diffuse, and granulomatous inflammation of the uvea, which occurs days, months, or years after penetrating ocular injury or intraocular surgery. The cause of the disease is still unknown but seems to be an autoimmune disease by reaction of delayed hypersensitivity mediated by T-Iymphocyte. There have been 4 cases reports on sympathetic ophthalmia domestically untill now, which occurred after ocular penetrating injury. The authors experienced two cases of sympathetic ophthalmia; one occurred after implantation of intraocular lens and the other occurred after cyclocryotherapy. A brief review of the related literatures is presented.
Autoimmune Diseases ; Hypersensitivity, Delayed ; Inflammation ; Lenses, Intraocular ; Ophthalmia, Sympathetic* ; Uvea

Sympathetic ophthalmia is rare, bilateral, diffuse, and granulomatous inflammation of the uvea, which occurs days, months, or years after penetrating ocular injury or intraocular surgery. The cause of the disease is still unknown but seems to be an autoimmune disease by reaction of delayed hypersensitivity mediated by T-Iymphocyte. There have been 4 cases reports on sympathetic ophthalmia domestically untill now, which occurred after ocular penetrating injury. The authors experienced two cases of sympathetic ophthalmia; one occurred after implantation of intraocular lens and the other occurred after cyclocryotherapy. A brief review of the related literatures is presented.
Autoimmune Diseases ; Hypersensitivity, Delayed ; Inflammation ; Lenses, Intraocular ; Ophthalmia, Sympathetic* ; Uvea

A case of Vogt-Koyanagi-Harada's Sindrome chiefly affected the anterior uvea has been clinically studied with several references. It was a typical one with hearing disturbances and was complicated with a secondary glaucoma. Following the iridectomy the I.O.P. was back to normal limit and with steroid therapy the inflammatory signs were relieved. After a considerabie period the anterior uveitis recurred. In this case the age of the patient was 10 years older than those Parker presented.
Child ; Glaucoma ; Hearing ; Humans ; Iridectomy ; Uvea ; Uveitis, Anterior

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss.
Adult* ; Diagnosis ; Hemorrhage ; Humans ; Magnetic Resonance Imaging ; Ophthalmology ; Pathologic Processes ; Referral and Consultation ; Retina ; Rupture ; Sclera ; Uvea

Neurofibromatosis (von Recklinghausen's disease) involves the eye in a great variety of clinical appearances. Secondary glaucoma with congenital ectropion uveae and mild buphthalmos in one eye and non-pigmented nodules in the iris of both eyes were observed in a 9-year-old girl with generalized neurofibromatosis. The patient also exhibited pigmented patches (cafe-au-lait spots) and multiple nodular masses of the skin. Two of the masses were excised and vitrified as plexiform neurofibroma, microscopically. This paper reports clinical, biomicroscopic, ophthalmoscopic, gonioscopic and histological findings in the patient.
Child ; Ectropion* ; Female ; Glaucoma* ; Humans ; Hydrophthalmos* ; Iris* ; Neurofibroma, Plexiform ; Neurofibromatoses* ; Skin ; Uvea*

In the past concepts of experimental immunogenic uveitis, immediate and delayed types of hypersensitivity seemed to be fairly clear-cut phenomena. But it is now apparent that many hypersensitivity reactions are not such clear-cut, they are often mixed and a number of basic mechanisms act in the development of tissue lesion of the uvea which is a shock tissue to experimentally administered foreign proteins, autogeno us tissue, microorganism and its products. The cellular reaction in immunogenic uveitis has been studied by many investigators; Delayed Arthus reaction could be occurred by a single intravitreal injection of the foreign protein, and both antibody-mediated hypersensitivity and delayed type of hypersensitivity also contributed to the ultimate Arthus reaction. It appeared probably that the autoimmune ocular reaction and the recurrent type of uveitis were of the delayed type of hypersensitivity, Much remains unanswered. Historical review of experimental immunogenic uveitis also is presented.
Arthus Reaction ; Humans ; Hypersensitivity ; Intravitreal Injections ; Research Personnel ; Shock ; Uvea ; Uveitis*

Fungal infection of the uveal tract are rare and only sporadic cases have appeared in the literature; recently, however, these have become more numerous since antibiotic or steroid therapy undoubtedly encourages the proliferation of concomitant fungal diseases. Diagnosis of mycotic uveitis was summarized; the clinical diagnosis and laboratory diagnosis. A positive diagnosis of a fungus as the cause of an intraocular infammation is justified only when the actual fungus can be identified in the ocular lesions. The laboratory diagnosis of a fungus etiology for uveitis may therefore be discussed under two headings-the methods used for the direct demonstration of a fungus and the immunologic procedures employed to establish a presumptive diagnosis of a infection by an avirulent fungus. If material is not available for histologic examination, culture or animal inoculation, the positive demonstration of a fungus etiology is not possible, and the diagnosis must remain a presumptive one. Such a presumptive diagnosis is made on the combination of the ocular symptomatology, the presence of associated systemic changes believed indicative of a fungus infection, the exclusion of other probable etiologic factors, and the immunologic response of the patient to fungus antigens. Epidemiologic studies of presumed ocular histoplasmosis at Wilmer institude were summarized. Modern journals of mycotic infection of uvea were reviewed.
Animals ; Clinical Laboratory Techniques ; Diagnosis ; Epidemiologic Studies ; Fungi ; Histoplasmosis ; Humans ; Uvea ; Uveitis

Malignant melanoma originated from the uvea is rare in the Orientals and children. A 1 and 1/3 year-old male infant gave a history of the white pupil and visual loss in the right eye for unknown period. The patient was visited another hospital and Water's view revealed suspicious calcification in the right orbit, so he was referred to our hospital. Ocular examination revealed opaque media due to numerous vitreous floaters and organized fibrinous materials. Re-examination of Water's view also revealed suspicious calcification in the right orbit, but confirmed a small calcific density by the C-T scanning examination. We performed enucleation of the right eye with clinical diagnosis of the retinoblastoma because of the patient's age, clilnical findings, radiologiacal findings and diffuse increased intrnocular soft tissue density in the C-T scanning examination. The histopathological diagnosis was malignant melanoma, mixed type, which was originated from the choroid with invasion of the ciliary body. The case reported here is unsuspected malignant melanoma which will exceptionally occur in the infant. A brief review of relating literatures is described.
Child ; Choroid ; Ciliary Body ; Diagnosis ; Fibrin ; Humans ; Infant* ; Male ; Melanoma* ; Orbit ; Pupil ; Retinoblastoma ; Uvea