26,492 women from various regions, including 207 communes (203 from the North and the Middle of Vietnam, 4 from Can Tho province) and 3 hospitals (2 in Ha noi and 1 in Can Tho) have been examined (from 1990 to 1996) in order to detect early lessions of cervix cancer by cytological screening. The results are summarized respectively as follows: 1. Communes (on the whole): SIL all types (3.36%) among them LSIL (2.49%) and HSIL (0.87%); invasive carcinomas (0.029%). In Can Tho province (corresponding rates): 3.69% with LSIL (2.71%), HI|SIL (0.98%) and invasive carcinomas (0.06%). 2. Hospitals. Ha noi hospitals: SIL all types (5.62%) with HSIL (2.28%) and invasive carcinomas (0.05%). Can Tho hospital (respectively): 4.57%, 2.38% and 2.75%. The diffirences betwween the morbidity and the ASR (100,000 people) in the North and in the South are discussed.
Uterine Cervical Neoplasms ; diagnosis

No abstract available.
Colposcopy* ; Early Diagnosis* ; Uterine Cervical Neoplasms*

Screening by Test Pap smear is a preventative method and the best way for early detection for cancer, currently. After the Conference organized in May 2001, the gynaecologic cancers agreed with Bethesda system and give out the guidelines to clinical treatments: sample quality, common classification, results, automatic and depended tests, training and suggestion. Cervical cancer is an important healthy issuse which need to be screening because of its regular characteristics and have an effective treatment methods in the first early period, in the long-term preclinical period and can be able to detect. Using test Pap smear has quickly screen result, less invasive procedures, low cost and can be accepted widely
Uterine Cervical Neoplasms ; diagnosis ; Vaginal Smears

OBJECTIVETo evaluate the clinical value of domestically manufactured digital colposcope system (SLC-2000) in the detection of early cervical lesions.

METHODSDuring a follow-up study of patients in Xiangyuan county, Shanxi, a high risk area for cervical cancer, a digital colposcope and an optical colposcope were randomly used for diagnosis, with pathology as the gold standard.

RESULTSIn 163 cervical biopsy specimens, 103 were diagnosed as chronic inflammation by histologic examination. Among 60 specimens which gave abnormal pathology, there were papilloma 1, cervical intra-epithelial neoplasia (CIN) I 37, CIN II 18 and CIN III 4. In 33 endocervical curettage specimens, 3 were pathologically positive. Comparing the digital and optical colposcope in diagnosing the positive lesions of > or = CIN I, the sensitivity of the former and latter were 83.3% and 95.0%, the difference without being statistically significant (P = 0.075). The specificity, positive predictive value, and accuracy of these two instruments were 61.2%, 21.4%, 55.6% and 41.3%, 69.3% 48.5%, with significant difference (P = 0.000, P = 0.035, and P = 0.000). In diagnosing > or = CIN II cervical lesions, these three results of the two instruments did not show any significant difference either. The negative predictive value of the digital and optical colposcope were 86.3% and 88.0%, also showing no significant difference (P = 0.075).

CONCLUSIONThe specificity, positive predictive value, and accuracy of the digital colposcope in diagnosing cervical lesions > or = CIN I are all superior to those of the traditional optical colposcope, even though the sensitivity of the latter is higher. There is no difference between the two instruments in diagnosing lesions > or = CIN II. Not only is domestic digital colposcope (SLC-2000) effective, but feasible and practical in the diagnosis, research and follow-up of cervical lesions.

Colposcopes ; Female ; Humans ; Predictive Value of Tests ; Sensitivity and Specificity ; Uterine Cervical Diseases ; diagnosis ; Uterine Cervical Neoplasms ; diagnosis ; Uterine Cervicitis ; diagnosis

Adult ; Female ; Humans ; Sarcoma, Myeloid ; diagnosis ; Uterine Cervical Neoplasms ; diagnosis

To evaluate the effectiveness of conization in the diagnosis of cervical cancer, the histopathologic finding of 464 consecutive cases were analized with respect to the cytology, punch biopsy and hysterectomy. Cold knife conization was performed under direct visualization(naked eye conization) from January, 1987 to Octorber 1994 at department of Obstetrics and Gynecology, Kosin Medical Center. The results were summerized as follows : 1. The rate of agreement and underdiagnosis of between pap smear and naked eye conization were 43.7% and 47%. 2. The rate of agreement and underdiagnosis of between punch biopsy and naked eye conization were 64.5% and 21.8% 3. Subsequent hysterectomy was done on the 382 case and their incidence of residual disease rate was 44.2%(169 cases). Their incidence of residual lesion was increased with severity of the carcinomatous change. 4. The rate of complication undergoing conization was 8.4%(39 cases).
Biopsy ; Conization* ; Diagnosis ; Gynecology ; Hysterectomy ; Incidence ; Obstetrics ; Uterine Cervical Neoplasms

OBJECTIVE: To investigate the necessity of colposcopically directed biopsy for more accurate detection of cervical neoplasm. METHODS: Cytology and colposcopically directed biopsy were performed in 114 patients and the patients were subsequently underwent conization or hysterectomy from January, 1998 to December, 2001. RESULTS: The complete diagnostic agreement of cytology with permanent biopsy was 57.9% (66 of 114) and the diagnostic agreement within one degree was 80.6% (92 of 114). The complete diagnostic agreement of colposcopically directed biopsy with permanent biopsy was 62.3% (71 of 114) and the diagnostic agreement within one degree was 85.1% (97 of 114). The difference between two tests was statistically significant (p<0.001). CONCLUSION: We concluded that colposcopically directed biopsy can reduce the false negative rate of cytology for screening test of cervical neoplasm. The difference between colposcopically directed biopsy and permanent biopsy was caused by inappropriate resection of the lesion and unskilled physician.
Biopsy* ; Conization ; Diagnosis* ; Humans ; Hysterectomy ; Mass Screening ; Uterine Cervical Neoplasms

Malignant mixed m llerian tumors are uncommon neoplasms of the female genital track that histologically consist of malignant epithelial and stromal components. Malignant mixed m llerian tumors generally occur in elderly woman and are associated with a poor prognosis. We experienced a case of malignant mixed m llerian tumor recieved pelvic irradiation for the uterine cervical cancer 11 years prior to the diagnosis of the tumor and report with a brief review of the literature.
Aged ; Diagnosis ; Female ; Humans ; Prognosis ; Uterine Cervical Neoplasms*

PURPOSE: To compare the sensitivity and staging accuracy of dynamically enhanced MR imaging(hereafter, DEI)and turbo spin-echo(TSE) T2-weighted imaging(hereafter, T2WI) in cases of cervical carcinoma. MATERIALS AND METHODS: MR images(T2WI and DEI) of 25 cervical carcinoma patients, diagnosed during surgery, were reviewed by tworadiologists. T2WI employed the TSE technique; dynamic MR imaging, the FLASH technique in the axial plane. DEimages were obtained immediately and at 30, 60, 120, and 180 seconds after rapid injection of Gd-DTPA. The degreeof visualization of the tumor, and its invasiveness, were graded as good, fair, or poor. By correlating thehistopathologic results, the accuracy of the two MR imaging techniques was compared. RESULTS: For tumorvisualization, T2WI was good in 13/25 cases (52%), fair in 3/25(12%), and poor in 9/25(36%); DEI was good in5/25(20%), fair in 7/25(28%), and poor in 13/25 cases (52%). CONCLUSION: For the detection and staging of cervicalcarcinoma, T2WI is superior to DEI. For the diagnosis and staging of cervical carcinoma, DEI is thereforeunnecessary.
Diagnosis* ; Gadolinium DTPA ; Humans ; Magnetic Resonance Imaging* ; Uterine Cervical Neoplasms*

OBJECTIVE: This study aims to assess the knowledge and attitudes of female adolescents aged 14-19 years old seeking consult at Philippine Children's Medical Center regarding cervical cancer screening and HPV vaccine.

DESIGN: Cross-sectional survey of mid to late adolescents.

METHODOLOGY: The survey questionnaire consists of 18 items in the domain of knowledge, attitudes, practice behaviors, barriers and demographic information. Survey forms in a sealed envelope were given to adolescents 14 to 19 years old after obtaining their assent and parents/guardians' consent.

RESULTS: There were a total of 107 respondents; majority belonged to the mid adolescents (14-16 years old), high school level and non sexually active 57%, 64% and 62% respectively. Most of the respondents (60%) were in a relationship or had a boyfriend, 61% engaged in a monogamous sexual relationship with their partners, 10% had 2 partners and 15% had more than 3 partners. There were significantly more late adolescents who are sexually active compared to mid adolescents (67.4% and 14.8%). Awareness of cervical cancer screening is only 23% of the surveyed adolescents (mean age 16.36). Majority of the sexually active respondents knew that HPV infection is through vaginal intercourse, and that pap smear is necessary even if no history of cancer in the family. More respondents with high education knew that avoidance of sexual intercourse, using condom and vaccination are all effective methods of HPV infection prevention. 53% of the respondents heard about HPV vaccine. Sources of information were mostly from the mass media. Majority were willing to receive the vaccine especially if given for free.

CONCLUSION: Knowledge on HPV and Cervical cancer prevention especially through pap smear is poor. Health education and improvement of personal practices should be emphasized as necessary factors for preventing HPV infection acquisition.

Human ; Adolescent ; Uterine Cervical Neoplasms- Diagnosis ; Papanicolaou Test ; Papillomaviridae